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Heart
Heart
9
Physiology
Professional
09/30/2011

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Term
Match: Pacemaker AP
1. Phase 4
2. Phase 0
3. Phase 3

a. "L"-type Ca2+ channels open
b. K+ permeability increase
c. influx of Na+ thru funny channels; "T" type channels open; K+ permeability decreases
Definition
1. C
2. A
3. B
Term
Pacemaker AP
1. (Influx/Efflux) of Na+ thru funny channels
2. K+ permeability (increases/decreases)
3. "(L/T)" type Ca2+ channels open
Definition
1. Influx
2. decreease
3. T
Term
Norepinephrine
1. Ica and If permeability (Increases/Decreases)
2. Ik permeability (Increases/Little effect)
3. Threshold potential (More/Less) negative
Definition
Norepinephrine
1. Increases Ica and If
2. Little effect on Ik
3. More negative- due to increased Ca2+
Term
Match:
Non-pacemaker AP
1. Influx of Na+ thru "fast" Na+ channels
2. Resting RMP
3. Ca2+ channel activates
4. Transient Potassium Efflux Channel (Ito) activates
5. Potassium channel activates

a. Phase 0
b. Phase 1
c. Phase 2
d. Phase 3
e. Phase 4
Definition
1. a
2. e
3. c
4. b
5. d
Term
Why is Phase 0 slower in pacemaker cells?
Definition
They don't have fast Na+ channels
Term
What causes the plateau of Phase 2 during a non-pacemaker cell AP?
Definition
Extended period of Ca2+ influx prolonging Phase 2.
Term
Describe the state of Na+ channels during an AP of a non-pacemaker cell. (Inactivated/Open/Closed)

1. Phase 4
2. Phase 0
3. Phase 1
4. Phase 2
5. Phase 3
Definition
1. Closed
2. Open
3. Inactivated
4. Inactivated
5. Closed
Term
Conduction of electrical impulses is slower through the ____ node.
Definition
AV node- it allows for complete atrial contraction and ejection of blood into the ventricles before the ventricles contract
Term
A positive orthdromic effect is created by (Sympathetic/Parasympathetic) stimulation.

A negative orthdromic effect is created by (Sympathetic/Parasympathetic) stimulation.
Definition
A positive orthdromic effect is created by (Sympathetic) stimulation. This increases the speed of impulse conduction thru AV node to ensure that all impulses get thru the AV node.
A negative orthdromic effect is created by (Parasympathetic) stimulation. This decreases impulse conduction thru the AV node.
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