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HDD_Lecture_2
Early development and embryology
30
Biology
Graduate
07/23/2014

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Cards

Term
What are advantages of sexual reproduction?
Definition
1) recombination mixture of paternal and maternal genes
2) selection in mate choice
Term
What is the dominated by time phase in meiosis?
Definition
Prophase I
Term
Describe chromosome position and composition in prophase I?
Definition
Chromosomes have replicated and consist of two tightly joined sister chromatids
Term
When grossing over occurs?
Definition
Chiasma can be observed in metaphase I.
Term
What are the phases of cell cycle and their typical duration?
Definition
G0, in which cells are resting or quiescent; G0 (days, weeks, years). G1, in which cells undergo RNA and protein synthesis necessary for entry in to S-phase; G1 (4 - 10 h). S-phase, in which cells undergo DNA replication; S (7 - 12 h). G2, in which cells undergo RNA and protein synthesis in preparation for mitosis;G2 (3 - 5 h). M-phase, in which cells undergo mitosis and cytokinesis. M (0.5 – 2 h).
Term
When sister chromatids are separated during meiosis?
Definition
Meiosis II
Term
Where Sertoli cells originate from?
Definition
Epithelium of seminiferous tubules
Term
Where sperm is produced?
Definition
seminiferous tubules
Term
Which cells sperm origanate from?
Definition
Primordial germ cells
Term
How recognize spermatogonium?
Definition
Ovoid nucleus that contains chromatin associated with the nuclear membrane
adjacent to the outer basement membrane of the sex cords
stem cell capable of regenerating itself as well as producing a new cell type
Term
What is the genetic content of spermatocyte I, II and spermatide?
Definition
Spermatocite I - 4n Spermatocite II - 2n Spermatide - n
Term
How much does it takes to produce a sperm in human?
Definition
65 days
Term
Outline the process of mammalian sperm construction
Definition
1)Construction of the acrosomal vesicle from the Golgi apparatus 2) formation of cap covers nucleus 3) Nucleus rotates so cap face basal membrane 4)flagellum is beginning to form from the centriole 5)the nucleus flattens and condenses, the remaining cytoplasm is jettisoned 6)the mitochondria form a ring around the base of the flagellum
Term
Which phase oocyte is waiting for fertilization in?
Definition
metaphase II
Term
Where we can see “lampbrush” appearance of chromosomes?
Definition
In oocyte in prophase I, when the synthesis of proteins and RNA occure
Term
When is first polar body produced?
Definition
At the end of meiosis I
Term
What is the PID / PGD?
Definition
Pre-implantation diagnostic, the cells are taken from embrio (cleavage state) or from polar body for analysis
Term
When implantation of the embrio occurs? In what stage?
Definition
Blastocyst is implanted on 5-6 day
Term
By what the histons are replaced in sperm?
Definition
Protamins
Term
When compactization occurs? Cavitation?
Definition
2.5 days and 3.5 days
Term
What is the acrosomal reaction?
Definition
It is a reaction between acrosome of the sperm and zona pellucida of the oocyte.
Term
What zona pelucida composed of?
Definition
Of three glycoproteins, ZP1,ZP2,ZP3
Term
Which glycoprotein in zona pellucida is essential for fertilization?
Definition
ZP3
Term
How oocyte is protected from double fertilization?
Definition
1) cortical reaction: after sperm invades egg, cortical granules are released and they dissolve zona pelucida,so other sperm could not go though 2)Ca wave: increase concentratuion of Ca in the egg's cytoplasm depolarizes it.
Term
What provides longterm blockage of polyspermy?
Definition
Cortical reaction
Term
Which tissues arise from ectoderm?
Definition
Skin, nerves, eyes
Term
Which tissues arise from endoderm?
Definition
Liver, lungs
Term
Which tissues arise from mesoderm?
Definition
Blood, muscles,cartilage
Term
What causes Angelman-Syndrom?
Definition
In a normal individual, the maternal allele in the chromosome 15 is expressed and the paternal allele is specifically silenced in the developing brain. If the maternal contribution is lost or mutated (by deletion,uniparental disomy, translocation, or single gene mutation), the result is Angelman syndrome.
Term
How many genes are imprinted?
Definition
1%
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