Shared Flashcard Set

Details

Gram Positive Bacilli
Exam 2
50
Pharmacology
Professional
05/01/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
bacillus: aerobic/anaerobic
Definition
aerobic
Term
bacillus: spore forming/non-spore forming
Definition
spore forming
Term
clostridium: aerobic/anaerobic
Definition
anaerobic
Term
clostridium: spore forming/non-spore forming
Definition
spore forming
Term
listeria: aerobic/anaerobic
Definition
aerobic
Term
listera: spore forming/non-spore forming
Definition
non-spore forming
Term
corynebacterium: aerobic/anaerobic
Definition
aerobic
Term
corynebacterium: spore forming/non-spore forming
Definition
non-spore forming
Term
Wounds contaminated with soil have a high probability of...
Definition
anaerobic spore forming bacteria
Term
"drumstick" morphology
Definition
Clostridium tetani

gram pos bacilli with endospore at one end
Term
What causes the CNS symptoms of tetanus?
Definition
spores of Clostridium tetani
Term
transmission of Clostridium tetani
Definition
traumatic implantation at puncture wounds, burn wounds, deliveries, non-sterile surgery
Term
tetanospasmin
Definition
toxin in tetanus that blocks exocytosis of inhibitory neurotransmitters, leading to painful muscle contractions
Term
vaccine for tetanus prevention
Definition
DTaP
TDaP
Term
What bacteria is normal flora of the colon but causes disease when it leaves the colon and has access to other tissue?
Definition
Clostridium perfringens
Term
bacteria responsible for gas gangrene
Definition
Clostridium perfringens
Term
transmission of Clostridium perfringens
Definition
implanted: wound infections
food poisoning: reheated meat dishes
Term
main mechanism of gas production in gas gangrene
Definition
fermentation of glucose (anaerobic metabolism)
Term
What bacteria can cause cellulitis with pain and massive tissue/muscle destruction with gas?
Definition
Clostridium perfringens
Term
most deadly type of gangrenous infection
Definition
gas gangrene
Clostridium perfringens
Term
common symptoms of gangrenous infections
Definition
weeping wounds
brown pus
foul or sweet smell
visible rotting flesh
Term
treatment of gas gangrene
Definition
penicillin
Term
What does inflammation of the meninges and ventricles produce?
Definition
-polymorphonuclear response
-increase in CSF protein content
-utilization of glucose in CSF
Term
What bacteria has "tumbling motility" morphology?
Definition
listeria
Term
What does listeria grow in?
Definition
non-immune macrophages
Term
toxin associated with listeria infection
Definition
listeriolysin O (LLO)
Term
listeria reservoir
Definition
GI tracts of animals
Term
transmission of listeria
Definition
-ingestion of raw milk/cheese of infected cows, deli meats
-vaginally during delivery to neonate
Term
infections caused by listeria
Definition
gastroenteritis
septicemia
neonatal meningitis (from mother)
Term
listeria infection responsible for neonatal meningitis
Definition
Listeria monocytogenes
Term
listeriosis
Definition
serious infection cause by eating food contaminated with Listeria monocytogenes

primarily affects persons of advanced age, pregnant women, newborns, and adults with weakened immune systems
Term
How is listeria killed?
Definition
pasteurization and cooking
Term
What aerobic gram pos bacillus has oval spores located centrally?
Definition
Bacillus anthracis
Term
transmission of Bacillus anthracis
Definition
inhaled: pneumonia
implanted: cutaneous lesions
Term
virulence factors of Bacillus anthracis
Definition
protective antigen
edema factor
lethal factor
anti-phagocytic capsule
Term
What bacteria causes the following:
-hemorrhagic necrosis of lymph nodes
-bacteriemia
-mediastinal edema
-cutaneous black eschar (necrosis and edema)
Definition
Bacillus anthracis
Term
What bacillus causes food poisoning?
Definition
Bacillus cereus
Term
bacteria associated with descending paralysis
Definition
Clostridium botulinum
Term
treatment of botulism
Definition
botulinum anti-toxin

effective against toxins A, B, and E

binds only to free circulating toxin and has no effect on nerves already damaged
Term
transmission of Clostridium botulinum
Definition
contaminated foods
infants: honey, dust
Term
botulinum toxin mechanism
Definition
blocks release of acetylcholine at the myoneuronal junction
Term
Clostridium botulinum incubation period
Definition
1-2 days
Term
symptoms of botulism
Definition
double vision (diplopia)
dry mouth
dysphagia
paralysis
Term
upper respiratory tract illness characterized by sore throat, low-grade fever, and an adherent membrane of the tonsils, pharynx, and/or nose
Definition
diphtheria
Term
small gram pos rods with club-shaped swelled ends but no spores
Definition
Corynebacterium diphtheriae
Term
What patients should respiratory diphtheria be suspected in?
Definition
those with membranous nasopharyngitis or obstructive laryngotracheitis who returned recently from areas where the disease is endemic or who were in close contact with persons who returned recently from such areas
Term
Corynebacterium diphtheriae only produces diphtheria toxin when...
Definition
lysogenized by beta phage
Term
C. diphtheriae strains that lock the _____ do not produce diphtheria toxin and do not cause the disease.
Definition
prophage
Term
With diphtheria toxins:
-oropharyngeal mucosa will show __________
-heart may show ___________
-nerve cells may have __________
Definition
pseudomembranes
myocarditis
laryngeal nerve palsy
Term
aerobic spore former found in rice and vegetables that causes food poisoning
Definition
Bacillus cereus
Supporting users have an ad free experience!