Shared Flashcard Set

Details

Gram Negative Pathogens
N/A
22
Pharmacology
Professional
02/16/2010

Additional Pharmacology Flashcards

 


 

Cards

Term
Moraxella (catarrhalis)
Definition

G NEGATIVE diplococci


Disease states:  Otitis media, CAP, sinusitis

-3rd behind S. pneumo & H. flu

 


 

Treatment:  Augmentin, Macrolides, Bactrim, Quinolones, 2nd & 3rd gen PO cephalosporins

Term
Enterobacteriaciae
Definition

G NEGATIVE


bacilli
AEROBIC

Term
Pseudomonas (aeruginosa)
Definition

G NEGATIVE


bacilli


AEROBIC


NON lactose fermenter

Commonly found in water sources--

OPPORTUNISTIC pathogen

 

Term
Acinetobacter (baumanii)
Definition

G NEGATIVE


bacilli


AEROBIC


NON lactose fermenting

Treatment:  Carbapenem OR Amp/Sulbactam

with Amikacin

 

Term
Stenotrophomonas (maltophilia)
Definition

G NEGATIVE


bacilli


AEROBIC


NON lactose fermenting

Bactrim = FIRST LINE txt

Zosyn also listed as possibility

 

Term
Haemophilus
Definition
G NEGATIVE, bacilli, AEROBIC
Term
Enterobacteriaciae Examples
Definition

Citrobacter (Lactose fermenter)


E.coli (LF)


Enterobacter (LF)


Klebsiella (LF)


Proteus


Salmonella


Serratia

 

Term

What are the defining characteristics of K.E.E.P.S. Enterobacteriaceae?

 

Definition

Aerobic Gram NEGATIVE rods


NON spore forming
Facultative anaerobes
Nitrate reductase POSITIVE
Enteric flora of LOWER GI tract
Commonly produce toxins

Term

K.E.E.P.S.

Enterobacteriaceae

Definition

Klebsiella pneumoniae


E. coli
Enterobacter
Proteus mirabilis
Serratia marcescens

Term
Which Enterobacteriaceae species are commonly SENSITIVE to therapy?
Definition

E. coli

 

 


Klebsiella

 

 


Proteus

 

Term

Which Enterobacteriaceae species are

nosocomial

(causing pneumonia & UTIs)

and are

commonly RESISTANT

(intrinsically) to

Ampicillin & 1st gen cephalosporins?

Definition

Serratia

 

 

 


 

Enterobacter

 

 

 


Citrobacter

 

Term

E. coli

 

(Characteristics & Diseases)

Definition

MOST COMMON facultative anaerobe in GI tract


Motile via flagellae, can acquire virulence factors


 

UTIs (MOST COMMON CAUSE)

 

Neonatal meningitis (LEADING CAUSE)

 

Nosocomial pneumonia

 

Peritonitis/Intra-abdominal infections

 

Diarrhea

(contaminated food, water, person to person contact)

Term
Klebsiella pneumonia
Definition

Sensitive OR MDR pathogen


 

UTIs

 

Bacteremia (2nd leading cause from GNRs)

 

Peritonitis

 

Pneumonia

(alcoholics, hospitalized pts)

(RED SPUTUM)

 

 

Term

Proteus

 

-mirabilis

-vulgaris

Definition

Common cause of CATHETER ASSOC UTIs

 

Secondary cause of pyelonephritis/bacteremia

Term
Enterobacter Treatment
Definition

Quinolones

 


Carbapenem

 


Anti-pseudomonal PCN+ BLI (+/- AG)

 


19% of patients DEVELOPED resistance to cephalosporins during cephalosporin therapy.

Term
Which disease states can be associated with Pseudomonas aeruginosa?
Definition

Otitis EXTERNA


Bacteremia
Nosocomial pneumonia
UTI
Endocarditis
Osteomyelitis

Term
Which two Gram NEGATIVE pathogens are associated specifically with respiratory conditions?
Definition

Haemophilus influenzae

 


Moraxella catarrhalis

Term

Haemophilus influenzae

 

(Type B)

Definition

Disease States:  meningitis, epiglottitis, septic arthritis


 

Prevention:  Vaccine at 2 mths old (3 doses total)

 


Treatment:  Ceftriaxone/Cefoxatime +/- Steroids

Term

Haemophilus influenzae

 

(Nontypeable)

Definition

Disease States:  Otitis MEDIA, CAP, URTI, sepsis

 

 

 


Treatment:  Augmentin, Macrolides, Bactrim, Quinolones, 2nd or 3rd gen PO cephalosporins

Term
Neisseria meningitidis
Definition

G NEGATIVE Encapsulate diplococci


Disease states: 

 

Sepsis (petechial rash)

 

Meningitis

(2nd HIGHEST cause in ADULTS)

(1st HIGHEST in PEDS)

Term
Neisseria gonorrhoeae
Definition

G NEGATIVE cocci


Disease states:

 

STD (gonorrhea)

 

Disseminated gonococcal infection (septic arthritis)

 

Pelvic Inflammatory Disease

Term
Treatment of Neisseria gonorrhoeae STD
Definition

Ceftriaxone

 

 


Quinolones

(NOT 1st line)

Supporting users have an ad free experience!