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GI Worms
Downstate > MS2 GI Block > GI Protozoal and Worm Infections
33
Medical
Graduate
12/12/2010

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Cards

Term
perianal pruritus, no eosinophilia
Definition
Enterobius vermicularis
Term
abdominal pain, nausea, diarrhea, anemia, eosinophilia, rectal prolapse
Definition
Trichuris trichiura
Term
mechanical and immune-mediated damage, eosinophilia, abdominal pain and obstruction, URI, systemic symptoms, emerges from orifices
Definition
Ascaris lumbricoides
Term
mechanical and immune-mediated damage, eosinophilia, abdominal pain, URI, skin rash, hypochromic anemia
Definition
Ancylostoma duodenale, Necator americanus
Term
mechanical and immune-mediated damage // post infection...1d: feet pruritus, 6d: bronchitis, 17d: abdominal pain and eosinophilia, 18d: diarrhea/constipation, 23-27d: larvae detectable in stools, 32d: bloody stool and LRQ pain // granuloma formation, larva currens, hyperinfection, bacteremia // chronic, silent infection may present acutely in immunosuppressed pts and may die within 140 days
Definition
Strongyloides stercoralis
Term
severe muscle pain, fever, marked eosinophilia, serum sickness-like symptoms (facial edema, splinter hemorrhages)
Definition
Trichinella spiralis
Term
severe epigastric pain, nausea vomiting 5-8h post-sushi-ingestion; swollen, hemorrhagic, eosinophilic granulomata
Definition
Anisakiasis
Term
mostly asymptomatic; CNS symptoms, GI symptoms, anemia, weight loss, malabsorption, B12 deficiency; post-sushi ingestion
Definition
Diphyllobothrium latum
Term
post-beef ingestion; mostly asymptomatic; changes in appetite
Definition
Taenia saginata
Term
adult tapeworm will cause mild GI symptoms // cysticercus will cause severe symptoms depending on where it deposits (i.e. cysticercus in eye)
Definition
Taenia solium
Term
SE Asia // pruritic skin rash with multiple penetration, systemic symptoms when disseminated; acute (Katayama syndrome): serum-sickness like, IC deposition, abdominal pain, splenomegaly; chronic: splenomegaly, portal hypertension, granuloma formation, pulmonary hypertension, CNS (epilepsy, paraplegia), and nephropathy symptoms // ALT and AST are normal
Definition
Schistosomiasis japonicum
Term
Korea, China, Japan, Taiwan, Vietnam // systemic symptoms (fever, chills), hepatomegaly, jaundice, adenoma of bile ducts, cholangiocarcinoma, calculus leads to Salmonella typhi infection and sepsis, pancreatic duct obstruction leads to pancreatitis
Definition
Clonorchis sinensis
Term
cosmopolitan //gradual onset; systemic symptoms (weight loss, malaise, edema, hyperemia), GI symptoms (diarrhea, dysentery, flask ulcers in cecum and recto-sigmoid colon, abdominal cramps, tenesmus), ameboma (1% freq), hepatomegaly, no dehydration and no fecal leukocytes // extraintestinal symptoms include abscesses (necrotizing lesions with peripheral trophozoites) in liver but no cysts
Definition
Entamoeba histolytica
Term
tropics, subtropics // pigs are reservoirs // mostly asymptomatic // circular lesions with raised borders found in colon similar to flask ulcers of E. histolytica, no extraintestinal lesions, diarrhea, dysentery, fever
Definition
Balantidium coli
Term
self-limited watery diarrhea of 1-2wks in healthy pts; severe diarrhea in AIDS pts; weight loss; acid-fast oocysts in stools
Definition
Cryptosporidium parvum, Cyclospora cayetanensis, Cycloisospora belli
Term
cosmopolitan, travelers, MSM // explosive diarrhea after 1-3 wks incubation, no appetite, malabsorption, flatulence, low-grade fever, nausea, vomiting // risk factors: achlorydia, low sIgA
Definition
Giardia lamblia
Term
Africa // pruritic skin rash with multiple penetration, systemic symptoms when disseminated; acute (Katayama syndrome): serum-sickness like, IC deposition, abdominal pain, splenomegaly; chronic: UG (difficult and painful micturation, ulcerated mucosa, cystitis, hematuria, carcinoma), liver/spleen (splenomegaly, portal hypertension, granuloma formation, hemolytic anemia), pulmonary hypertension, and CNS (epilepsy, paraplegia) symptoms // ALT and AST are normal
Definition
Schistosoma haematobium
Term
pruritic skin rash with multiple penetration of non-human pathogenic strains, Katayama syndrome
Definition
cercarial dermatitis (Schistosoma)
Term
no tissue migration, does not free-live in soil // adult in cecum; eggs are laid on perianal skin; eggs get airborne and are ingested; eggs hatch in small gut; larvae migrate to cecum
Definition
Enterobius vermicularis
Term
no tissue migration, does not free-live in soil // adults attach in cecum (detach, reattach), eggs passed in stool, eggs mature in soil for 10d, eggs are ingested, eggs hatch in small gut and larvae migrate to cecum
Definition
Trichuris trichiura
Term
tissue migration, does not free-live in soil // adults in small gut, eggs passed in stool, eggs mature in soil for 10d, eggs are ingested, eggs hatch in small gut, larvae travel to heart and lungs, coughed up, and swallowed
Definition
Ascaris lumbricoides
Term
tissue migration, free lives in soil // adults attach to small gut (and do not move), lay eggs, eggs pass in stools, eggs hatch in soil, rhabitiform larvae are free feeding, filariform larvae penetrate skin, travel to lungs and heart, are coughed up and swallowed, and mature in small gut
Definition
hookworms
Term
tissue migration, free lives in soil // adults in colon, lay eggs, eggs hatch in gut, larvae passed in stools, rhabitiform larvae free feed, filariform larvae penetrate skin, travel to heart/lungs, coughed up and swallowed, and mature in colon // larvae penetrate mucosa allowing Gram- bacteria to populate blood
Definition
Strongyloides stercoralis
Term
humans ingest uncooked pork with encysted larvae, larva excyst in stomach, mature in gut, lay larvae, larvae travel to muscle and encyst in muscle; remain infective for 5-10y; humans are dead end hosts
Definition
Trichinella spiralis
Term
adults in stomach of marine mammals, eggs passed in stools, eggs hatch in water, crustaceans eat larvae, fish eat crustaceans and larvae migrate to peritoneal cavity, marine mammals eat fish, larvae mature into adults in stomach // humans eat fish, larvae penetrate stomach mucosa--no maturation, no adults
Definition
Anisakiasis
Term
eggs in stool, eggs hatch in freshwater releasing coracidia, crustaceans eat coracidia and they mature to procercoid, fish eat crustaceans and procercoid migrates to muscle and matures to plecocercoid; human eats fish and plercoceroid attaches to small gut
Definition
Diphyllobothrium latum
Term
adult in small gut, gravid proglottids in feces, gravid proglottids ruptures releasing eggs, cows eat eggs, eggs hatch into oncospheres, oncospheres travel to muscle and become cysterci in cow muscle, humans eat beef and cysticerci mature into adults, adults attach to gut mucosa
Definition
Taenia saginata
Term
humans can be an intermediate host (cysticercosis) as well // adult in small gut, eggs/gravid proglottids in stool, pig eats eggs, eggs hatch into oncospheres, oncospheres travel to muscle and become cysticerci in 3-4mo, humans eat pork, cysticerci become adults in small gut // autoinfection: adult's gravid proglottids can be carried back into stomach via reverse peristalsis, hatch into eggs, etc.; or via superinfection with fecal-oral contamination
Definition
Taenia solium
Term
adults in colon/bladder, eggs pass in feces, eggs hatch into miracidia, miracidia infect snails and become cercariae, cercariae penetrate humans and become schistosomula, schistosomula travels to liver first then heart/lung, then to colon/bladder // male, when with female, sheds tegument to prevent Ab/C' binding by producing discoid and membranous bodies; males' spiny tubercles are more pronounced and numerous when female is not present; female migrates to male following chemotactic lipid gradient
Definition
Schistosomiasis japonicum/hamabotium/mansoni
Term
adults in bile duct, eggs in feces, snails eat eggs, fish eat snails and eggs become cercariae, cercariae encyst in fish muscle and become metacercariae, humans eat fish, metacercariae excyst in duodenum, travel to bile duct and mature into adults
Definition
Clonorchis sinensis
Term
cyst is heat, low pH, and chlorine resistant; and is resistant to C'-mediated lysis // only cysts are found in gut lumen // produces lectin, neuraminidase, and glycosidase for attachment; collagenase and amebopore to disrupt enterocyte layer; and phosphoglucomutase with beta-band // erythrophagocytosis
Definition
Entamoeba histolytica
Term
cholera-like toxin; colonizes all of GI
Definition
Cryptosporidium parvum
Term
non-invasive, attaches to mucosa like a suction cup // villi blunting
Definition
Giardia lamblia
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