Term
What are some causes of acute sialadenitis?
What disease is Chronic Sialadenitis associated with |
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Definition
Causes of acute
Upper respiratory viruses
Staph/Strep
Chronic: Rheumatoid Arthritis |
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Term
| What salivary gland does sialolithiasis typically occur and how is it treated |
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Definition
Submandibular
Treatment: Surgery or Shockwave lithotripsy |
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Term
What are benign lymphoepithelial cysts?
What disease is it associated with? |
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Definition
Multilocular cysts with glandular or squamous epithelium surrounded by florid lymphoid hyperplasia
Association: HIV |
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Term
How does Sjogern's Syndrome(Mickulicz's Syndrome) affect the salivary glands
What is the major risk? |
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Definition
Lymphocytic(B-Cell) infiltrate with myoepithelial proliferation
Malt Lymphomas can develop |
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Term
| What salivary gland is most likely to develop cancer and which gland is most likely to have a malignancy? |
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Definition
Parotid-Most common
Sublingual-Most Malignancies |
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Term
What is the most common tumor of the salivary glands?
What is the most common malignant salivary gland tumor? |
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Definition
Most common: Pleomorphic Adenoma
Most common Malignant: Mucoepidermoid |
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Term
| Who is most likely to get a pleomorphic Adenoma of the salivary glands |
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Definition
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Term
| What is the gross and micro appearance of a Pleomorphic Adenoma of the salivary glands |
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Definition
Gross: Swellings(Superficial) or dysphagia(deep)
Rubbery
Extensions into healthy salivary
Micro: Epithelial/myoepithelial and stromal components(possibly bone/cartilage)
Stroma stains magenta in Disquith stain |
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Term
| What is the risk of multiple recurances of Plenomorhic adenocarcinoma of the salivary glands |
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Definition
| Conversion to carcinoma ex pleomorphic adenoma |
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Term
| What is the histology of carcinoma ex pleomorphic adenoma |
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Definition
| Mixed differentiation of Carcinoma(epithelial) and sarcoma(Stroma) |
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Term
Who is most likely to get Warthin's tumor
What gland does it effect?
What is the gross and micro |
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Definition
Men 50-60 years old
Gland:Parotid
Gross:
Oval mass
Capsule
Brown viscous fluid
Micro:
Double epithelium
Dense lymphocytic infiltrate surrounding
Oncocytic(granular and pink) cytoplasm |
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Term
| What is the gross and micro appearance of Mucoepidermoid Carcinoma |
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Definition
Gross:
Cystic(low grade)
Firm Pink<->yellow(high grade)
Micro:
4 Cells-Squamous, Clear cell, Intermeadiate, Mucous
Low Grade-More Cysts, more mucous
High Grade-More Squamous, intermeadiate |
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Term
Who commonly gets Adenoid Cystic Carcinoma
What is the micro appearance?
In what gland is it the most common malignancy? |
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Definition
Men or women 50-70
Micro
Tubular, Cribiform, or Solid(Worst)
PAS(+) BM
Perineural Invasion
Malingnancy: Minor salivary glands
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Term
What age/sex is most likely to get Acinic Cell Carcinoma of the salivary gland?
What is the gross and Micro appearance? |
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Definition
Better prognosis
Males 30-40
Gross
Encapsulated
Micro
Hypercellular serous cells w/o ducts
Lymphocytic Infiltrate
Solid<->Papillary/Cystic<->Tubular Structure |
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Term
Which tumor has:
Lymphoctic infiltrate
Perineural Invasion
Double Epithelium
Stroma stains with Disquith
PAS(+) Hyaline production
Hypercellular serous glands w/o ducts
Bone or Cartilage |
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Definition
Lymphoctic infiltrate: Warthins, Acinic Cell
Perineural Invasion: Adenoid Cystic
Double Epithelium: Warthin's
Disquith(+) stroma: Pleomorphic Adenoma
PAS(+) Hyaline: Adenoid Cystic
Hypercellular serous w/o ducts: Acinic
Bone/Cartilage: Pleomorphic Adenoma
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Term
| What malignant salivary gland tumor predominantly affects the parotid gland? |
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Definition
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