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GI Diseases
GI Diseases
21
Biology
Graduate
02/20/2013

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Term
GERD
Definition
-gastroesophogeal reflux disease due to incompetent LES (hiatal hernia)
Term
Dumping Syndrome
Definition
-incompetent pyloric spincter
-rapid water loss
Hypovolemia --> hypotension --> syncope
Term
Achalasia
Definition
-LES doesn't relax
-acquired deficiency
-absence of neurons or transmitters
-Blocks both solids AND water
-causes mega-esophagus
Term
Strictures
Definition
-Scar tissue or a pattern of constriction that prevents dilation of esophagus
Term
Diffuse Spasm
Definition
-multiple esophageal contractions simultaneously instead of one coordinated smooth motion
-food goes up and down
Term
Pouches
Definition
-sacs for in esophogeal wall
-food and acid can go in
Term
Esophageal varices
Definition
-swelling of vessel that ruptures and bleeds
Term
Barrett's
Definition
-occurs when you have reflux disease that damages lower esophagus.
-pre-cancerous
Term
Gastroparesis
Definition
-in Diabetes Mellitus
-impaired vagus function causes decreased contractile function
-sympthoms: nausea, early satiety, vomiting "old food" 1-3 hours after eating
-lots of volume remaining in stomach after 4 hours
Term
Pyloric Stenosis
Definition
-usually congenital
-newborns projectile vomit
Term
Spruce
Definition
-loss of villi and microvilli in small intestine
-can be caused by gluten intolerance (celiac) or tropical agents
-decreases absorptive surface and enzyme secretion
Term
Hirschsprung's Disease
Definition
-congenital lack of interstital cells of cajal in colon
-unable to relax internal anal spincter
-megacolon and constipation
Term
Volvulus
Definition
-twisting of bowel leads to obstruction
Term
Intussception
Definition
-inception of the bowel
Term
Xerostromia
Definition
-congenitital
-absence of salivation causes dry mouth, tooth decay
Term
Sjogren's Syndrome
Definition
-chronic autoimmune disease
-fibrosis and atrophy of glands --> decreased salivation
Term
Cholestasis
Definition
-obstruction of biliary tree
-caused by liver/pancreatic disease, stones, tumors, obstruction, etc
-causes: lipid malabsorption in Small intestine, less pigmentation in feces, greater pigmentation in urine, elevated bilirubin in plasma, jaundice, icterus**
Term
Gastritis (antral)
Definition
-increases acid secretion
-stimulates G cells,
-inhibits D cells
Term
Gastritis (body)
Definition
-decreases acid production
-inhibits parietal and ECF cells
Term
Transient Neonatal Pseudo-obstruction
Definition
-newborns
-no contraction in GI tract
-cells of Cajal didn't migrate to correct location
Term
Hartnup's Disease
Definition
-inability to absorb dietary Trp results in Niacin deficiency
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