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gentics
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28
Biology
11th Grade
12/01/2010

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Term
Gene
Definition
Piece of DNA that codes for a protein (heritable factor that contains a specific characteristic)
Term
Allele
Definition
specific form of a gene (one from mom, one from dad)
Term
genome
Definition
entire genetic info of an organism
Term
gene mutation
Definition
random rare change in genetic material
Term
what causes gene mutation
Definition
nitrogen base deletion, addition, substitution
Term
in sickle cell anemia, _ _ _ becomes _ _ _
Definition
GAG (glutamic acid) becomes GUG (valine)
Term
genotype
Definition
representation of a pair of alleles possesed by an organism
Term
phenotype
Definition
physical charecteristics (blue eyes)
Term
locus
Definition
particular position on homologous (same) chromosome of a gene
Term
test cross
Definition
Testing a suspected heterozygote plant or animal by crossing it with a known homozygous recessive
Term
type A blood
Definition
IA (dominant)
Term
type B blood
Definition
IB (dominant)
Term
type o
Definition
i (recessive)
Term
number of individual chromosomes and pairs
Definition
46, 23 pairs
Term
female _ _
male _ _
Definition
XX
XY
Term
the _ chromosome is slightly larger than the _ chromosome
Definition
the X chromosome is slightly larger than the Y chromosome
Term
karyotype
Definition
: Photographs of the chromosomes found in a cell, arranged by size and shape
1. Cells are stained and prepared in microscope slides
2. Photographs are taken
3. Images are cut out and separated, manually or via computer
4. Arranged in pairs by size and position of centromeres (center)
Term
prior to karyotyping ______ or _______________ are used to obtain fetus cells for pre-natal diagnosis of __________ abnormalities
Definition
CVS (chorionic villis sampling)
amniocentesis
chromosomal
Term
amniocentesis
Definition
Hypodermic needle used to extract some amniotic fluid around the developing fetus which leads to using the cells for karyotype
Term
CVS
Definition
Tissue samples are obtained from the placenta’s fingerlike projections into the uterine wall
Term
in down's syndrome, the disorder is on chromosome pair _____, giving it the other name ___________
Definition
21
trisomy 21
Term
PCR (polymerase chain rxn)
Definition
copy DNA in a lab
Term
DNA profiling
Definition
use of DNA to reveal owner's identity
Term
human genome project
Definition
mapping dna nitrogen bases
Term
gene transfer
Definition
cutting and pasting genes to make raw
organisms
Term
cloning
Definition
duplicating cells and animals
Term
Outline the steps of polymerase chain reaction to copy and amplify minute quantities of DNA
Definition
1. start with small quantity of DNA
2. thermocycler copies all nucleic acids in the sample to make millions of copies of DNA
3. solves the problem using gel electrophoresis
Term
gel electrophoresis
Definition
DNA fragments are placed into small wells in the gel
gel is exposed to an electric current (positive on one side, negative on the other)
smallest and most charged particles move faster and farther than the lesser charged and heavier ones)
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