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GENETICS
GENETICS
65
Biology
Undergraduate 3
03/20/2008

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Term
What happens during interphase?
Definition
Preparation for mitotic phase
Term
What happens during G1?
Definition
Synthesis of enzymes required during S phase
Term
What happens during S phase?
Definition
DNA synthesis
Term
What happens during G2 phase?
Definition
Anything that hasn't doubled, doubles here. Lasts til mitosis
Term
What happens during the mitotic phase?
Definition
Splitting of the nucleus and cytoplasm. Daughter cells
Term
What is a chromatid?
Definition
Each of the two daughter strands of a duplicated chromosome joined at the cnetromere during mitosis. One half of a replicated chromosome. Intermediate stage.
Term
How many are in a chromosome?
Definition
Two
Term
What is the relationship between a chromatid and a DNA molecule?
Definition
ASK HIM
Term
How many chromatids are in a chrom at G1
Definition
none
Term
How many chromatids are in a chrom right after S?
Definition
two
Term
What is a centromere
Definition
joins two chromatids together
Term
What is a kinetchore and what does it do?
Definition
A specialized protein structure at the centromere. Spindle fibers attach to it.
Term
What happens during prophase?
Definition
Breaks into vesicles. Chroms coil. Microtubules begin to assemble. Nuclear envelope disappears
Term
Prometaphse?
Definition
Chroms completely condense. Spindal fibers attach.
Term
Metaphase?
Definition
Chroms line up on equater. Equidistant from the pole. 2 DNA molecules.
Term
Anaphase?
Definition
Begins when centromeres divide. Chromosomes are pulled apart by spindal fibers. 1 DNA molecule and 1 chromatid
Term
Telophase and cytokinesis
Definition
begins when chromatids reach the poles. nuclear envelope starts to form. Chromosomes start to unwind. microtubules begin to breakdown.
Term
how many chromatids in each phase?
Definition
ask him
Term
what is a diploid?
Definition
2n. 2 sets of chromosomes. most cells in the body are b/c gametes (haploids) come together
Term
how does one homologous pair of chromosomes differ from all other pairs?
Definition
Carry the same genes
Term
What is a gene?
Definition
set of instructions that code for a particular characteristic
Term
what is a locus? what is its relationship to a gene?
Definition
Phsical location on a chromosome. At this locus you find the blood-type gene
Term
What are the two main functions of meiosis?
Definition
To go from diploid to haploid, and to maintain genetic diversity
Term
What are the two mechanisms used to promote genetic diversity?
Definition
crossing over and independent assortment
Term
where does independent assortment occur?
Definition
Metaphase I
Term
An organism has 2n=16, how many gametes can be produced?
Definition
2^8
Term
Crossing over occurs during what phsae?
Definition
prophase I
Term
what crosses over?
Definition
non-sister chromatids
Term
What is the phenotype/genotype of F2 generation monohybid?
Definition
phenotype: 3:1
genotype: 1:2:1
Term
What is a dihybrid cross?
Definition
two individuals that differ in the alleles at two different loci
Term
how many different gameetes can an F1 individual, heterozygous produce?
Definition
4
Term
what was consistent in F1?
Definition
all heterozygous
Term
What is the geneotypic ratio for F2 of dihybrid?
Definition
1:2:2:4:1:2:1:2:1
Term
What does the law of segregation state? When does it occur, what does it describe?
Definition
Each gene pair separates during gamete formation, so each gamete receives only one copy of the gene. Anaphase I, separating homologous pairs.
Term
What does the law of independent assortment state?
Definition
Which allele of a gene pair goes into a paticular gamete is independent of metaphse I. This is why we do the pT, Pt, PT etc. cuz we don't know where they'll go. This occurs in metaphase I
Term
What is incomplete dominance?
Definition
Neither allele can be expressed in the heterozygote, so we can't talk in terms of dominant or recessive. This is where the white and red carnations produce pink ones.
Term
What about linked genes?
Definition
If alleles are on the same chromosome, independent assortment is no longer relevant.

Even though its dihybrid, it acts just like a monohybrid because they're linked together, so punnett square has only four not sixteen.
Term
What is co-dominance
Definition
both alleles fully expressed in zygote.
Term
Multiple alleles?
Definition
More than two alleles for a given locus. Only two can be inherited. ABO blood system.
Term
Sex-linked traits. What is hemizygous?
Definition
males only get one dose of x chromosome gene
Term
What building blocks go into DNA?
Definition
four nitrogenous bases
Term
What are the purines?
Definition
adenine and guanine
Term
What are the pyrimidines
Definition
Thiamine and C...
Term
How do purines and pyimidines differ?
Definition
purines are bigger
Term
Write on card about all the people
Definition
Term
What is DNA synthesis and where does it occur?
Definition
Going from 1 DNA molecule to 2 DNA molecules. During S Phase. Going from chromosomes made of one chromatid to chromosomes made of 2.
Term
What is the semiconservative model?
Definition
one half of the strand is new.
Term
What is transcription?
Definition
the synthesis of RNA using DNA as a template on which to make it. Copy the information for making a protein. Opposite code of DNA except with a U
Term
Where does transcription occur?
Definition
nucleus
Term
What is translation?
Definition
Synthesis of protein using genetic information encoded in RNA. Need RNA, ribosomes and amino acids. Proteins made by ribosoms using the RNA info.
Term
Where does translation occur?
Definition
ribosomes
Term
What is an mRNA?
Definition
the kind of RNA that encodes amino acid sequences
Term
What is tRNA?
Definition
Converts codons to one letter, amino acid words. Serves as an interpreter
Term
How is mRNA, tRNA, anticodons and codons related?
Definition
tRNA has anticodons which recognize the mRNA codons and lift them to where they need to go.
Term
How are ribosomes and tNA related?
Definition
ribosome brings tRNA in and creates a chain of amino acids until it reaches a stop codon. This is wehre protein is released.
Term
What 4 ways does RNA differ from DNA?
Definition
RNA polymerase, one strand AGUC, transcription
Term
What is RNA synthesis?
Definition
transcription
Term
What is actually transcribed?
Definition
the DNA nucleotides, bases...
Term
What is polypeptide synthesis?
Definition
translation
Term
How is genetic code read?
Definition
tRNA
Term
What is a codon?
Definition
the genetic instructions for the amino acide sequence of a polypeptide chain. Written in DNA and RNA as a series of three-base words
Term
What else do ribosomes do?
Definition
build polypeptides
Term
mRNA is AAA, what amino acid?
Definition
AAA
Term
tRNA is AAA, what amino acid?
Definition
UUU
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