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Genetics Unit 1: Molecular Genetics
Cells - units of biology, DNA and RNA, Proteins and translation, The genetic code is universal, Regulation of gene expression
41
Biology
Undergraduate 3
09/08/2012

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Term
prokaryote
Definition
has no nucleus
Term
eukaryote
Definition
has a defined nucleus
Term
cell with circular chromosome
Definition
prokaryotes
Term
shape of a prokaryotic chromosome
Definition
circular
Term
chromosomes
Definition
thread-like strands composed of DNA
Term
how do prokaryotes divide? eukaryotes?
Definition
binary fission; mitosis
Term
transformation
Definition
shows that bacteria are capable of exchanging DNA
Term
DNA
Definition
polymers that contain a varying sequence of 4 nucleotides
Term
how nucleotides pair (which ones to which)
Definition
thymine-adenine, guanine-cytosine
Term
kind of bond that binds nucleotides
Definition
hydrogen bond
Term
3 parts of a nucleotide
Definition
dioxyribose sugar, phosphate group, and a base
Term
when the DNA double helix separates
Definition
denature
Term
when the DNA double helix comes back together
Definition
renature/hybridize
Term
shape of eukaryotic chromosome
Definition
linear
Term
centromere
Definition
"restriction" in mid-chromosome
needed for proper segregation during mitosis & meiosis
Term
telomere
Definition
specialized structure at ends of linear chromosome
enzyme telomerase
Term
how DNA replicates
Definition
"moulding" / complementary shapes
Term
how DNA is replicated
Definition
semiconservative replication
Term
hydrophobic
Definition
repel water "afraid of water" -- bases
Term
hydrophilic
Definition
attracts water -- outside of DNA (sugar-phosphate)
Term
uracil
Definition
RNA's equivalent to thymine -- a different base
Term
ribose sugar
Definition
sugar used in RNA instead of deoxyribose
Term
sugar used in RNA instead of deoxyribose
Definition
ribose sugar
Term
transcription
Definition
process of recording DNA through the use of RNA
Term
types of RNA & their functions
Definition
mRNA, tRNA, rRNA

mRNA: (messenger)carries out the actions of genes, carries DNA's message from the nucleus into the cytoplasm
tRNA: carries amino acids around during translation
rRNA: puts amino acids together in chains
Term
codon
Definition
combination of three nucleotides in a row
Term
exon
Definition
part of the DNA sequence that is translated to RNA during transcription splicing
Term
intron
Definition
part of the DNA sequence that is NOT translated to RNA during transcription splicing
Term
splicing
Definition
part of transcription when only part of the DNA is read and expressed in RNA
Term
RNA interference
Definition
inhibits gene expression by creating a double-stranded RNA that leads to RNA degradation in some areas of the RNA
Term
what determines higher order structure in proteins?
Definition
primary structure
Term
primary structure is determined by
Definition
amino acid structure
Term
secondary structure
Definition
common motifs such as alpha helix -- spiral
Term
tertiary structure
Definition
how the various regions of secondary structure fold with respect to one another
Term
quaternary structure
Definition
multiple peptide chains & how they associate
Term
enzyme
Definition
catalyzes reactions
Term
functions of proteins
Definition
Enzymes
Structural components
Pumps/channels
Regulatory proteins
Convert chemical energy to motion
Term
AUG
Definition
start codon
Term
start codon
Definition
AUG
Term
UUA, UAG, UGA
Definition
stop codons
Term
stop codons
Definition
UUA, UAG, UGA
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