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Genetics Quiz #2
The Cell Cycle
85
Biology
Undergraduate 3
09/12/2012

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Term
What is an organism’s
DNA, with its arrays of genes, organized into structures?
Definition
chromosome
Term
What are two major processesinvolved in the genetic continuity
of nucleated cells?
Definition
Mitosis & Meiosis
Term
What are sex cells?
Definition
gametes or spores
Term
What is the genetic
material making up chromosomes (unfolds and uncoils)
into a diffuse network within the nucleus not undergoing division?
Definition
chromatin
Term
What is an
outer covering that defines the cell boundary and delimits
the cell from its immediate external environment?
Definition
plasma membrane
Term
What is an outer covering whose major component is a polysaccharide
called cellulose in plant cells?
Definition
cell wall
Term
Animal cells have a covering over the
plasma membrane, referred to as the?
Definition
glycocalyx or cell coat
Term
Molecules that act as recognition sites that transfer specific chemical signals across the cell membrane into
the cell are?
Definition
receptor molecules
Term
The presence of a nucleus and other membranous organelles
is the defining characteristic of __________.
Definition
eukaryotic organisms
Term
What is a membrane-bound
structure that houses the genetic material, DNA, which is
complexed with an array of acidic and basic proteins into
thin fibers in eukaryotic cells?
Definition
nucleus
Term
What is an amorphous component where
ribosomal RNA (rRNA) is synthesized and where the initial
stages of ribosomal assembly occur?
Definition
nucleolus
Term
What are portions of DNA
that encode rRNA are collectively referred to as the ________.
Definition
nucleolus organizer region (NOR)
Term
What lacks a nuclear envelope and membranous organelles?
Definition
prokaryotic organisms
Term
What is a long, circular
DNA molecule that is compacted into an unenclosed region?
Definition
nucleoid
Term
What is the remainder of the eukaryotic cell within the plasma
membrane that includes a variety of extranuclear cellular organelles?
Definition
cytoplasm
Term
What is a nonparticulate, colloidal material that surrounds and encompasses the cellular organelles?
Definition
ctyosol
Term
What is an organelle that compartmentalizes the cytoplasm, greatly increasing the surface area available for biochemical synthesis?
Definition
endoplasmic reticulum (ER)
Term
What are sites where genetic information contained in messenger RNA (mRNA) is translated into proteins?
Definition
ribosomes
Term
__________ is found in
most eukaryotes, including both animal and plant cells,
and are the sites of the oxidative phases of cell respiration.
These chemical reactions generate large amounts of
the energy-rich molecule adenosine triphosphate (ATP).
Definition
mitochondria
Term
What is found in plants, algae, and someprotozoans,and are associated with photosynthesis, the major
energy-trapping process on Earth?
Definition
chloroplasts
Term
Animal cells and some plant cells also contain a pair
of complex structures called ________.
Definition
centrioles
Term
What are cytoplasmic
bodies located in a specialized region?
Definition
centrosome
Term
These play an important role in the movement of chromosomes
as they separate during cell division. They are composed
of arrays of microtubules consisting of polymers of
the protein tubulin.
Definition
spindle fibers
Term
What is a constricted
region, whose location establishes the
general appearance of each chromosome?
Definition
centromere
Term
What is the shorter arm above the centromere?
Definition
p-arm
Term
What is the longer arm below the centromere?
Definition
q-arm
Term
somatic cells derived from
members of the same species contain this identical number
of chromosomes.
Definition
2n
Term
When the lengths and centromere placements of all such
chromosomes are examined with the exception of sex chromosomes, they exist in pairs with regard to these two properties, and the members
of each pair are called
Definition
homologous chromosomes
Term
the physical appearance of different
pairs of homologous chromosomes
Definition
karyotype
Term
chromosomes
is equal to one-half the diploid
number.
Definition
haploid
Term
the genetic
information contained in a haploid set
of chromosomes
Definition
genome
Term
Homologous chromosomes
contain identical gene sites along their lengths called
Definition
locus
Term
In a population of members of the same species,many different alternative forms of the same gene called
Definition
alleles
Term
single-celled fertilized eggs in a multicellular diploid organism
Definition
zygote
Term
genetic material is partitioned into daughter cells
during nuclear division,
Definition
karyokinesis
Term
Karyokinesis is followed by cytoplasmic division or _________
Definition
cytokinesis
Term
events that occur from the completion
of one division until the completion of the next division
Definition
cell cycle
Term
the initial stage of the cell cycle and the replication of the DNA of
each chromosome.
Definition
interphase
Term
This period, during which DNA is synthesized,occurs before the cell enters mitosis
Definition
S-phase
Term
Investigations of this nature demonstrate two periods
during interphase when no DNA synthesis occurs, one before and one after the S phase.During both of these intervals, as
well as during S, intensive metabolic activity, cell growth, and
cell differentiation are evident.
Definition
G1 and G2
Term
By the end of G2, the volume
of the cell has roughly doubled, DNA has been replicated,
and ________ is initiated.
Definition
mitosis
Term
one of the early stages of this event is migration of two pairs of centrioles to opposite ends of the cell.
Definition
prophase
Term
two parts of each chromosome
are ______ _______ because the DNA
contained in each of them is genetically identical, having
formed from a single replicative event.
Definition
sister chromatids
Term
Sister chromatids are
held together by a multi-subunit protein complex called
Definition
cohesin
Term
the period of chromosome movement
Definition
prometaphase
Term
the chromosome configuration following migration.
Definition
metaphase
Term
unique protein family protects cohesin from being degraded by separase at the centromeric regions.
Definition
shugoshin
Term
During
this phase, sister chromatids of each chromosome, held together only at their centromere regions, disjoin from one another and are pulled to opposite ends of the cell.
Definition
anaphase
Term
migrating chromosome as anaphase proceeds
Definition
daughter chromosome
Term
At its beginning of this final stage of mitosis, two complete sets of
chromosomes are present, one set at each pole. The most
significant event of this stage is cytokinesis, the division
or partitioning of the cytoplasm.
Definition
telophase
Term
Checkpoint that monitors the size the cell has achieved since its previous mitosis and also evaluates the condition of the DNA.
Definition
G1/S checkpoint
Term
checkpoint where DNA is monitored prior to the start of mitosis.
Definition
G2/M checkpoint
Term
checkpoint where the successful formation of the spindle
fiber system and the attachment of spindle fibers to the kinetochores
associated with the centromeres are monitored.
Definition
M checkpoint (Spindle Assembly checkpoint)
Term
first division in meiosis I (because the number of centromeres, each representing one chromosome, is reduced by one-half).2n to n
Definition
reductional division
Term
second division during meiosis II (because the number of centromeres
remains equal); sister chromatids separated into daughter cells
Definition
equational division
Term
First, as in mitosis, chromatin present
in interphase thickens and coils into visible chromosomes. And each chromosome is a double structure,
held together by the molecular complex called cohesin. Second,
unlike mitosis, members of each homologous pair of
chromosomes pair up, undergoing synapsis. Third, crossing
over occurs between chromatids of synapsed homologs.
Definition
prophase I
Term
homologous chromosomes
form pairs; that is, they synapse (or undergo) _________.
Definition
synapsis
Term
During the leptotene stage, the interphase
chromatin material begins to condense, and the chromosomes,
though still extended, become visible; where chromosome fibers begin to condense
Definition
leptonema
Term
The chromosomes continue to shorten and
thicken during the zygotene stage;where each homologous chromosome pair is joined together by a synaptonemal protein complex. The process is called synapsis and the synapsed chromosomes are called bivalent or tetrads (four chromatids)
Definition
zygonema
Term
In the transition from the zygotene to the pachytene stage, the chromosomes continue to coil and shorten, and further development of the synaptonemal
complex occurs between the two members of each bivalent.This leads to synapsis, a more intimate pairing; where DNA exchanges occur between non-sister chromatids. A cross-shaped structure called a chiasma (chiasmata plural) forms at the point of exchange.
Definition
pachynema
Term
During the ensuing diplotene stage, it is even more apparent that each tetrad consists of two pairs of sister
chromatids. Within each tetrad, each pair of sister chromatids begins to separate; where the synaptonemal complex begins to disappear but chiasmata is still visible;where the synaptonemal complex begins to disappear but chiasmata is still visible
Definition
diplonema
Term
The final stage of prophase I
chromosomes pull farther apart, but nonsister chromatids remain loosely associated at the chiasmata. As separation proceeds, the chiasmata move toward the ends of the tetrad; Chromosomes are maximally condensed and chiasmata migrate toward the ends of the chromosome. Homologous pairs begin to pull away from each other so chiasmata are clearly seen. Nucleoli and nuclear membrane disappear and spindle apparatus begin to form.
Definition
diakinesis
Term
the chromosomes have maximally shortened and thickened. The terminal chiasmata of each tetrad are visible and appear to
be the major factor holding the nonsister chromatids together;Bivalents (tetrads) are oriented on the equatorial plane.
Definition
metaphase I
Term
Cohesin is degraded between sister chromatids,except at the centromere region, which, as in mitosis, is protectedby a shugoshin complex. Then, one-half of each tetrad(a dyad) is pulled toward each pole of the dividing cell;Chiasmata dissolve, centormeres do not separate so whole chromosomes (2 sister chromatids) move to opposite poles of the cell. This reduces the chromosome number from 2n to n.
Definition
anaphase I
Term
reveals a nuclear membrane
forming around the dyads; is completed when the nuclear membrane reforms around the chromosomes at either end of the cell.
Definition
telophase I
Term
is essential if each
gamete or spore is to receive only one chromatid from each
original tetrad.
Definition
meiosis II
Term
each dyad is composed of one pair of sister chromatids attached by the common centromeric region;Spindle apparatus reforms and chromosomes re-condense
Definition
prophase II
Term
the centromeres are positioned on the equatorial plate,the shugoshin complex is degraded, and the centromeres separate; Chromosomes line up along the equatorial plane.
Definition
metaphase II
Term
reveals one
member of each pair of homologous chromosomes present at each pole. Each chromosome is now a monad; Nuclear membranes reform around chromosomes at opposite poles.
Definition
telophase II
Term
In ____________, the formation of ova (sing. ovum),
or eggs, occurs in the ovaries, the female reproductive
organs
Definition
oogenesis
Term
M phase is itself composed of two tightly coupled processes:________, in which the cell's chromosomes are divided between the two daughter cells, and ___________, in which the cell's cytoplasm physically divides
Definition
mitosis and cytokinesis
Term
Cells that have temporarily or reversibly stopped dividing are said to have entered a state of _________ called G0 phase
Definition
quiescence
Term
cells that have permanently stopped dividing due to age or accumulated DNA damage are said to be
Definition
senescent
Term
The first phase within interphase is called __ ; during this phase the biosynthetic activities of the cell, which had been considerably slowed down during M phase, resume at a high rate; Required for cell growth and preparation of DNA synthesis
Definition
G1 phase
Term
phase starts when DNA synthesis commences, when it is complete, all of the chromosomes have been replicated; synthesis and replication of genome
Definition
S phase
Term
is required for cell growth and cell division into two daughter cells.
Definition
cell cycle
Term
phase is needed or cell growth and preparation of mitosis
Definition
G2 phase
Term
phase in which cells segregate duplicated chromosomes
Definition
M phase
Term
Upon perturbation of DNA replication by drugs that interfere with DNA synthesis,cells activate ______ that arrests cell cycle at G2/M transition until DNA replication is complete
Definition
DNA replication checkpoint
Term
arrests cell cycle at M phase until all chromosomes are aligned on spindle.
Definition
spindle checkpoint
Term
detects abnormality in the cytoskeleton and arrests cell cycle at G2/M transition.
Definition
morphogenesis checkpoint
Term
division of a haploid (n) or diploid (2n) cell into two duplicate daughter cells;the division of a nucleus (karyokinesis) into two duplicate nuclei, each with identical sets of chromosomes.(duplication)
Definition
mitosis
Term
special kind of cell division in which the chromosome number is reduced in half. This is how the chromosome number in a life cycle changes from diploid (2n) to haploid (n). (reduction)
Definition
meiosis
Term
Cytoplasmic division initiated by the assembly of contractile elements at the equatorial plate in animal cells
Definition
cytokinesis
Term
Centromeres split and separated chromosomes are pulled to opposite poles of the cell.
Definition
anaphase II
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