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Genetics Exam 1 Review
Exam 1 Review
108
Biology
Undergraduate 2
02/04/2013

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Term
Transmission Genetics
Definition
the study of heredity and genes on chromosomes
Term
Molecular Genetics
Definition
the physical nature of the genes
Term
Population Genetics
Definition
changes in genetic content of population (how the genetics evolve)
Term
Six Common Model Organisms
Definition
Fruit fly, E. Coli bacteria, Roundworm, Thale Cress Plant, House Mouse, Baker's yeast
Term
Gregor Mendel
Definition
Principles of heredity, independent assortment, law of segregrations, worked with 7 characteristics of pea plants
Term
Charles Darwin
Definition
theory of evolution via natural selection
Term
Walter Sutton
Definition
proposed that genes were on chromosomes
Term
Thomas Morgan
Definition
fruit fly model, population genetics
Term
Flow of genetic informaiton
Definition
DNA > RNA > Protein
Term
Kinds of Prokaryotes
Definition
Bacteria, archea
Term
Mutations
Definition
Permanent heritable changes in DNA
Term
leptotene
Definition
The chromosomes contract and become visible
Term
zygotene
Definition
the chromosomes continue to condense, begin synapsis
Term
pachytene
Definition
the chromosomes become shorter and thicker, crossing over occurs
Term
Diplotene
Definition
the centromeres of the paired chromosomes move apart
Term
chiasma
Definition
the place where homologs are crossed
Term
diakinesis
Definition
the chromosomes condense and the chiasmata move to the ends of the chromosomes
Term
Tetrads
Definition
the four part structure that forms during the prophase of meiosis. Consist of two homogolous chromosomes
Term
Gene
Definition
a genetic factor (region of DNA) that helps determine a characteristic
Term
Allele
Definition
One of two or more alternate forms of a gene
Term
Locus
Definition
Specific place on a chromosome occupied by an allele
Term
genotype
Definition
Set of alleles possessed by an individual organism
Term
Phenotype
Definition
The appearance or manifestation of a character
Term
Heterozygote
Definition
An individual possessing two different alleles at a locus
Term
Homozygote
Definition
An individual organism possessing two of the same alleles at a locus
Term
Character
Definition
An attribute or feature
Term
epistatsis
Definition
When one allele effects how another allele is expressed
Term
Dominance
Definition
Phenotype of the heterozygote is the same as the phenotype of one of the homozygotes
Term
Incomplete Dominance
Definition
Phenotype of the heterozygote is intermediate (falls within the range) between the phenotypes of the two homozygotes
Term
Codominance
Definition
Phenotype of the heterozygote includes the phenotypes of both homozygotes
Term
Penetrance
Definition
percentage of a population having a particular genotype that express the expected phenotype
Term
Expressivity
Definition
the degree to which a characteristic is expressed in an individual
Term
Recombination
Definition
Term
When does recombination occur?
Definition
Meiosis
Term
Linked genes demonstrate independent assortment. T/F
Definition
False
Term
Genetic phenomenon of segregation is due to:
Definition
separating of parental alleles after metaphase I
Term
Five Stages of Prophase I?
Definition
Leptotene, Zygotene, Pachytene, Diplotene, Diakinesis
Term
Stages of Mitosis
Definition
Prophase, Metaphase, Anaphase, Telaphase, cytokensis
Term
Stages of Meiosis
Definition
Prophase I, Metaphase I, Anaphase I,Telophase I, Cytokinesis, Interkinesis, Metaphase II, Anaphase II, Telophase II, Cytokinesis
Term
Two mechanisms responsible for genetic variation?
Definition
crossing over and the random distribution of maternal and paternal chromosomes
Term
Microsporocytes
Definition
Male diploid plant cell
Term
Microspores
Definition
Male haploid plant cell
Term
Megasporocytes
Definition
Female diploid plant cell
Term
Megaspores
Definition
Female haploid plant cell
Term
Endosperm
Definition
when the other sperm fuses with two nuclei to form the endosperm
Term
Prophase I
Definition
Chromosomes condense, homologous chromosomes synapse, crossing over takes place, nuclear envelope breaks down and mitotic spindle forms
Term
Metaphase I
Definition
Homologous pairs of chromosomes line up on the metaphase plate
Term
Anaphase I
Definition
The two chromosomes (each with two chromatids) of each homologous pair seperate and move toward opposite poles
Term
Telophase I
Definition
Chromosomes arrive at spindle poles
Term
Cytokinesis I
Definition
The cytoplasm divides to produce two cells, each having half the original number of chromosomes
Term
Interkinesis
Definition
In some types of cells, the spindle breaks down, chromosomes relax, and a nuclear envelope re-forms, but no DNA synthesis takes place
Term
Prophase II
Definition
Chromosomes condense, the spindle forms, and the nuclear envelope disintegrates
Term
Metaphase II
Definition
Individual chromosomes line up on the metaphase plate
Term
Anaphase II
Definition
Sister chromatids separate and move as individual chromosomes toward the spindle poles
Term
Telophase II
Definition
Chromosomes arrive at the spindle poles; the spindle breaks down and nuclear envelope reforms
Term
Cytokinesis
Definition
The cytoplasm divides
Term
Crossing Over
Definition
exchange of genes between nonsister chromatids from different homologous chromosomes
Term
Cohesin
Definition
a protein that holds the chromatids together and is the key to the behavior of chromosomes in mitosis and meiosis
Term
Shugoshin
Definition
protein that protects the cohesin protein, only occurs in anaphase I
Term
monohybrid crosses
Definition
those between parents that differed in a single characteristic
Term
Principle of segregation
Definition
states that each individual diploid organism possesses two alleles for any particular characteristic that can separate when gametes are formed
Term
Chromosome theory of heredity
Definition
the theory that genes are located on chromosomes
Term
testcross
Definition
one individual of unknown genotype is crossed with another individual with homozygous recessive genotype for the trait in question
Term
wild type
Definition
the common allele for a character, is often symbolized with a plus sign.
Term
Principle of independent assortment
Definition
Mendel, states that alleles at different loci separate independent of one another
Term
goodness of fit chi-square test
Definition
used to evaluate thee role of chance in producing deviations between observed and expected values
Term
dioecious
Definition
organism that has either male or female parts
Term
autosomes
Definition
nonsex chromosomes
Term
Haplodiploidy
Definition
sex is determined by the number of chromosomes in the cell instead of by sex cells
Term
genic sex determination
Definition
when sex is genetically determined but there are no obvious differences in the chromosomes of the males and females; there are no sex chromosomes
Term
pseudoautosomal regions
Definition
small regions containing the same genes
Term
ZZ-ZW Sex Determination
Definition
females are heterogamatic and males are homogamatic
Term
Sequential hermaphroditism
Definition
each individual animal can be both male and female but not at the same time
Term
Turner Syndrome
Definition
When there is only 1 X chromosome
Term
Klinefelter Syndrome
Definition
When there are 2 X chromosomes and a Y
Term
Poly-X Females
Definition
When there are multiple X chromosomes
Term
Genic Balance System
Definition
sex is determined by ratio of the number of x chromosomes to the number of total chromosomes.
Term
Roles of sex Chromosomes
Definition
contain genetic information, at least 2 X chromosomes are needed to be fertile, multiple X chromosome may cause mental problems, Y is needed for a male, at least 1 X is needed for development
Term
Sex-linked characteristics
Definition
characteristics that are determined by genes located on the sex chromosomes
Term
nondisjuction
Definition
when the two X chromosomes fail to separate during anaphase I
Term
hemizygous
Definition
carrying only 1 copy of a gene. Ex - genes that are X-lined
Term
dosage compensation
Definition
equalizes the amount of protein produced by X-linked genes in the two sexes
Term
Metacentric
Definition
centromere is in the center
Term
submetacentric
Definition
centromere is just above the middle
Term
acrocentric
Definition
centromere is toward the top
Term
telocentric
Definition
centromere is at the very top
Term
Prophase
Definition
mitotic spindle form
Term
Prometaphase
Definition
the nuclear envelope disintegrates
Term
Metaphase
Definition
Chromosomes align on the metaphase plate
Term
Anaphase
Definition
Sister chromatids separate, becoming individual chromosomes that migrate toward the spindle poles
Term
Telophase
Definition
Chromosomes arrive at spindle poles, the nuclear envelope reforms and the condensed chromosomes relax
Term
cytokinesis
Definition
cytoplasm divides; cell wall forms in plant cells
Term
backcross
Definition
cross between a F1 genotype and either of the parental genotypes
Term
backcross
Definition
cross between a F1 genotype and either of the parental genotypes
Term
Advantages of using a fruit fly
Definition
small size, short generation time, lay 400-500 eggs, easy to culture in a lab, small genome, large chromosomes, many mutations available
Term
dosage compensation
Definition
when there are too many X chromosomes, it equalizes the amount of protein produced by X-linked genes in the two sexes
Term
Barr body
Definition
when one of the X chromosomes in inactivated
Term
gene interaction
Definition
when the effects of genes at one locus depend on the presence of genes at the other loci
Term
hypostatic gene
Definition
the gene that is masked by the epistatic gene
Term
complementation test
Definition
parents that are homozygous for different mutations are crossed
Term
complementation
Definition
when an individual possessing two mutant genes has a wild-type phenotype and is an indicator that mutations are nonallelic genes
Term
sex-limited characteristics
Definition
characteristics that are expressed in only one sex
Term
cytoplasmic inheritance
Definition
when some of the genetic information is contained in the cytoplasm; cytoplasmic genes are usually inherited from only one parent
Term
genetic maternal effect
Definition
nuclear genotype of the maternal parent
Term
genomic imprinting
Definition
genes whose expression is affected by the sex of the transmitting parent; epigentics
Term
discontinuous characteristics
Definition
characteristics that only have a few variations (ex: blood type)
Term
pleiotrophy
Definition
when one gene affects multiple characteristics
Term
phenocopy
Definition
when the pheotype that is expressed due to enviornmental factors is the same as one produced by a certain genotype
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