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Genetics Exam 2
Linkage, recombination, eukaryotic gene mapping,principles of heredity, chromosome variation, chemical nature of genes, ect.
32
Biology
Undergraduate 3
10/20/2010

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Term
Linked genes
Definition
genes located on the same chromosome
Term
linkage group
Definition
genes located together on the same chromosome.
Term
Non recombinant (parental) gamete
Definition
contains only the original combinations of genes present in the parents.
Term
Non recombinant (parental) progeny
Definition
possesses the original combinations of traits possessed by the parents.
Term
recombinant gamete
Definition
possesses new combination of genes.
Term
recombinant frequency
Definition
proportion of recombinant progeny produced in a cross.
Term
coupling (cis) configuration
Definition
arrangement in which two or more wild-type genes are on one chromosome and their mutant alleles are on the homologous chromosome.
Term
repulsion (trans) configuration
Definition
arrangement in which each chromosome contains one wild-type (dominant) gene and one (recessive) gene.
Term
interchromosomal recombination
Definition
recombination among genes on different chromosomes.
Term
intrachromosomal recombination
Definition
recombination among genes on the same chromosome.
Term
genetic map
Definition
map of the relative distances between genetic loci, markers, or other chromosome regions determined by rates of recombination.
Term
physical map
Definition
map of physical distances between loci, genetic markers, or other chromosome segments. measured in base pairs.
Term
map unit (m.u.)
Definition
unit of measure for distances on a genetic map. 1 map unit = 1% recombination.
Term
Morgan
Definition
100 map units
Term
two-point testcross
Definition
cross between an individual heterozygous at two loci and an individual homozygous for recessive alleles at those loci.
Term
three-point testcross
Definition
cross between an individual heterozygous at three loci and an individual homozygous for recessive alleles at those loci.
Term
interference
Definition
Degree to which one crossover interferes with the additional crossovers.
Term
coefficient of coincidence
Definition
ratio of observed double crossovers to expected double crossovers.
Term
genetic marker
Definition
Any gene or DNA sequence used to identify a location on a genetic or physical map.
Term
deletion mapping
Definition
technique for determining the chromosomal location of a gene by studying the association of its phenotype or product with a particular chromosome deletions.
Term
chromosome mutation 9
Definition
difference from the wild-type in the number or structure of one or more chromosomes.
Term
chromosome rearrangement 9
Definition
change from the wild-type in the structure of one or more chromosomes.
Term
chromosome duplication 9
Definition
mutation that doubles a segment of a chromosome.
Term
tandem duplication 9
Definition
duplication oft a chromosome segment that is adjacent to the original segment.
Term
displaced duplication 9
Definition
chromosome rearrangement in which the duplicated segment is some distance from the original segment, either on the same chromosome or on a different one.
Term
reverse duplication 9
Definition
duplication of a chromosome segment in which the sequence of the duplicated segment is inverted relative to the sequence of the original segment.
Term
chromosome deletion 9
Definition
loss of a chromosome segment.
Term
pseudodominance 9
Definition
expression of a normally recessive allele owing to a deletion on the homologous chromosome.
Term
haploinsufficient gene 9
Definition
must be present in two copies for normal function. If one copy of the gene is missing, a mutant phenotype is produced.
Term
chromosome inversion 9
Definition
rearrangement in which a segment of a chromosome has been inverted 180 degrees.
Term
paracentric inversion 9
Definition
Chromosome inversion that does not include the centromere in the inverted region.
Term
pericentric inversion 9
Definition
chromosome inversion that includes the centromere in the inverted refion.
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