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Genetics Chp 4 terminology
exam II
43
Biology
Undergraduate 2
02/23/2010

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Term
Alfred Sturtevant
Definition
Term
Ascus
Definition
in fungus, a sac that encloses a tetrad or an octad ascospores.
Term
Ascospore
Definition
a sexual spore form certai fungus species in which spores are found in a sac called as ascus.
Term
Bateson and Punnett
Definition
Term
Centimorgan (cM)
Definition
the distance between two linked gene paires where 1 percentof the product of meiosis are recombinant; a unit of distance in a linkage map
Term
Chi Square analysis
Definition
statistical test that used to determine the probability of obtaining observed proportions by chance, under a specific hypothesis
Term
chiasmata
Definition
A crossed-shaped structure commonly observed between nonsister chromatids in meiosis; the site of crossing over
Term
Chromosome map
Definition
a representation of all chromosomes in te genome as lines, marked with postion of genes known from their mutant phenotype, plus molecule markers. based on analysis of recombinant frequency.
Term
Cis conformatin
Definition
in a heterozygous having mutant sites within a gene or within a gene cluster, the arrangement A1A2/a1a2.
Term
Crossing over
Definition
the exchange of corresponding chromosomes parts between homologs by breakage and reunion
Term
DNA fingerprints
Definition
the autodiographic banding pattern produced when DNA is digested with a restriction enzyme that cuts outside a family of VNTRs 9 variable number of tendem repeats) anda southern blot of the electrophoretic gel is probed with a VNTR-specific probe. unlike true fingerprints, these patterns are not unique to each individual organism
Term
Double crossovers
Definition
two crossover in a chromosomal region under study
Term
Interference
Definition
a measure of the independance of crossover from each other, calculated by subtracting the coefficient of coincidence from 1
Term
Linkage disequilibrium
Definition
deviation in the frequency of haplotypes in a population from the frequency expected if the alleles at different loci are associated at random
Term
Linkage map
Definition
a chromosomes map; an abstract map of chromosomal loci that is based on recombinant frequencies.
Term
Linked genes
Definition
the situation on which two genes are on the same chromosome as deduced by recombinant fequencies less than 50 percent
Term
Loci
Definition
Term
Lod Scores
Definition
cumulative statistics that summarizes evidence supporting a specific linkage value
Term
Map units (m.u.)
Definition
Term
Meiotic division
Definition
Term
MI asci
Definition
Term
Microsatellite DNA
Definition
a type of repetitive DNA consisting of very shortsuch repeats such as dinucleotide
Term
Minisatellite marker
Definition
a difference in dna at the same locus in two genomes that is due to different repeat length of a microsatellite
Term
MII asci
Definition
Term
Mitotic division
Definition
Term
Molecular markers
Definition
a site of DNA heterozygosity, not necessarily associated with phenotypic variaiton, used as atag for a particular chromosomL LOCUS
Term
Multiple crossovers
Definition
Term
Octad
Definition
an ascus containing eight ascospores, produced in species in which the tetrad normally undergoes a postmeiotic mitotic division
Term
Parental types
Definition
Term
Parental chromosomes
Definition
Term
Physical map
Definition
Term
Recombination map
Definition
a chromosome map in which the position of loci shown are based on recombinant frequencies
Term
Recombinant frequency (RF)
Definition
the proportion of recombinant cells
Term
Recombinant types
Definition
individual organism or cell having the a genotype produced by recombination
Term
Recombinant chromosomes
Definition
Term
RFLPs
Definition
a difference in dna sequence between individuals or haplotypes that is recognized as different restrictionn fragment length. a probe for this dna region will hybridize to different-sized fragments within restriction digests of dna from these two alleles.
Term
SSLPs
Definition
the presence of different numbers of short or simple repetitive elements at one particular locus in different homologous chromosomes; heterozygotes serve as useful markers for genome mapping.
Term
SNPs
Definition
A nucleotide-pair difference at a given location in the genome of two or more naturally occurring individuals.
Term
Test cross
Definition
A cross of an individual organism homozygous for one or more recessive alleles; used in a testscore
Term
Thomas Hunt Morgan
Definition
Term
Three point test cross
Definition
a testscore in which one parent has three heterozygous gene pair
Term
Trans conformation
Definition
in a heterozygote with two mutant sites within a gene or gene cluster, the arrangement a1 +/+ a2
Term
VNTRs
Definition
a chromosomal locus at which a particular repetitive sequence is present in different numbers in differnt individuals or in the two different homologs in one haploid individual
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