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Genetics Ch 12: Gene Transcription and RNA modification
Genetics: Analysis and Principles
19
Biology
Undergraduate 2
09/20/2011

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Term
gene
Definition
segment of DNA that is used to make a functional product, either an RNA molecule or polypeptide
Term
transcription
Definition
synthesizing RNA from a DNA sequence
Term
structural genes
Definition
encode amino acid sequence of a polypeptide
Term
mRNA "messenger"
Definition
type of RNA, generated on template of structural gene that is then sent to the ribosome for translation
Term
translation
Definition
polypeptide synthesis using the RNA molecule as "blueprint"
Term
central dogma of genetics
Definition
mRNA is transcribed from DNA, sequence in mRNA determines sequence of amino acids in polypeptide, one or more polypeptides assemble into a functional protein, proteins ultimately determine an organism's traits
Term
gene expression
Definition
overall process in which information within a gene is used to produce a functional product (i.e. polypeptide)
Term
promoter
Definition
sequence of DNA that provides site to begin transcription
Term
terminator
Definition
sequence of DNA that specifies end of transcription
Term
template strand/coding strand
Definition
DNA strand complementary to RNA strand produced (NOT acted upon)
Term
non template strand
Definition
DNA strand that does not match the coding strand (involved in synthesis of RNA)
Term
colinearity
Definition
one-to-one correspondence between the sequence of codons in the dna coding strand and the amino acid sequence of the polypeptide
Term
exons
Definition
coding sequences in eukaryotic dna
Term
introns
Definition
"intervening sequences" non coding DNA in eukaryotes
Term
RNA splicing
Definition
excision of introns in the faithful RNA structure
Term
nucleolus
Definition
location of cleavage of small rRNAs and assembly of ribosomal subunits
Term
exonuclease
Definition
enzyme that cleaves covalent bond be tween two nucleotides at the end of one strand
Term
endonuclease
Definition
can cleave covalent bone between two nucleotides still within a strand
Term
ribozyme
Definition
RNA molecule that functions as a catalyst
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