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GENE 302
Lecture 18
11
Biology
Undergraduate 4
03/05/2012

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Term
Monoploid
Definition
a single chromosome set that is repeated in polyploids
Term
haploid
Definition
the chromosome complement of the gametes of a species
Term
Nullisomy
Definition
loss of both members of a homologous pair of chromosomes (2n-2) where n refers to the haploid number.
Term
in humans, a nullisomic zygote would have how many chromosomes?
Definition
44
Term
monosomy
Definition
the loss of a single chromosome (2n-1)
Term
trisomy
Definition
the gain of a single chromosome (2n+1) this means there are three homologous copies on one chromosome
Term
tetrasomy
Definition
the gain of two homologous chromosomes (2n+2) this does not mean gain of any two extra chromosomes, but rather the gain of two homologous chromosomes
Term
in monosomy, individuals have at least
Definition
a single copy of every gene present in the remaining homolog
Term
in monosomy, although individuals have at least a single copy of every gene, if one of those genes is represented by a lethal allele,
Definition
the unpaired chromosome condition will result in death
Term
lethality could also result from
Definition
haploinsufficiency
Term
haploinsufficiency is if
Definition
a single copy recessive gene is unable to provide adequate function for sustaining the organism
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