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Gen Bio: Cellular Bio
Kaplan notes for DAT study
83
Biology
Undergraduate 1
11/06/2017

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Term

Summarize The Cell Theory

Definition
  1. All Living things are composed of cells
  2. The cell is the basic unit of life
  3. The chemical reactions of life take place inside the cell.
  4. Cells arise only from pre-existing cells
  5. Cells carry the genetic information in the form of DNA. This genetic material is passed on from parent to daughter cell.
Term

What are the organelles inside the cell?

Definition

  • nucleus
  • ribosomes
  • endoplasmic reticulum
  • golgi apparatus
  • vescicles
  • vacuoles
  • lysosomes
  • mitochondria
  • chloroplasts
  • centrioles
Term

Name the 6 kingdoms

Definition
  1. Bacteria
  2. Archea
  3. Protista
  4. fungi
  5. plantae
  6. animalia
Term

What are the two types of cells?

Definition
Eukaryotes and prokaryotes
Term

How does the fluid mosaic model function?

Reference phospholipids, location of the hydrophillic heads and hydrophobic tails and what can cross the plasma membrane with and without assistance.

Definition

The cell membrance consists of a phospholipid bilayer with proteins embedded throughout. The lipids and many layers of proteins can move freely within the membrane.

The phospholipid molecules are long, nonpolar, hydrophobic, "fatty" chains of carbons and hydrogens face each other, with the phosphorous-containing polar, hydrophilic heads facing outwards.

The plasma membrane is readily permeable to both small, non-polar, hydrophobic molecules such as oxygen and small polar molecules such as water. Small charged particles are usually able to cross the membrane through protein channels. Larger charged molecules and ions cross the membrane with the assistance of carrier proteins.

Term

What is the function of the nucleus?

Definition

The nucleus controls the activities of the cell,

including cell division

Term

What are histones?

Definition

  • Histones are structural proteins inside the nucleus that help form chromosomes.
  • The DNA winds around histones to make it more compact.
  • histones are involved in regulation of gene transcription.
Term

Where does the ribosomal RNA synthesis occur?

Definition

The nucleolus

Term

Where is the site of protein production?

Definition

The ribosomes are the site of protein production.

Term

What is the function of the endoplasmic reticulum?

Definition

The Endoplasmic Reticulum is a network of membrane-enclosed spaces involved in the transport of materials through out the cell, particularly materials destined to be secreted by the cell.

Term

What are the two types of Endoplasmic Reticulum?

What are each of their functions?

Definition

1. Smooth ER: Does not contain ribosomes, so it is not involved in protein synthesis but instead is involved with the metabolism and the production of lipids.

2. Rough ER: Contains the ribosomes and plays an important role in the production of protein.

Term

What is the function of the golgi apparatus?

Definition

The golgi apparatus receives vesicles and their contents from the smooth ER and then modifies them (via processes such as glycosylation) repackages them into vesicles and distributes them to the cell surface via exocytosis.

Term

What is the function of the mitochondria?

Definition

The Mitochondria is the site of aerobic respiration within the cell and the supplier of energy (ATP)

Term

What organelle is composed of an outer and inner phospholipid bi layer?

Definition

The mitochondria.

Term

What is the fluid inside the cytoplasm?

Definition

The fluid inside the cytoplasm is the cytosol.

Term

What is cyclosis?

Definition

Cyclosis is streaming movement within the cytoplasm.

Term

What are vesicles/vacuoles?

Definition

Vesicles and vacuoles are membrane-bound sacs involved in the transport and storage of materials that are ingested, secreted, processed, or digested by the cell.

Vacuoles are larger than vesicles and are more likely to be found in plant cells and not animal cells.

Term

What is the structure and function of centrioles?

Definition

Centrioles are composed of microtubules and are involved in spindle organization during cell division.

Term

Where are centrioles located in animal cells?

Definition

A pair of centrioles are oriented at right angles to each other that are found in the Centrosome region.

Term

What is the function of the centrosome?

Definition

It organizes the microtubules and helps regulate the progression of the cell cycle.

Term

Do plant cells contain centrioles?

Definition

Plant cell do not contain centrioles

Term

What is the structure and function of lysosomes?

Definition

Lysosome Structure: Membrane-bound vesicles that contain hydrolytic enzymes

Function: Involved in intracellular digestion by breaking down the material ingested by the cell.

Term

What is autolysis?

Definition

A dying cell may self-destruct by rupturing the lysosome membrane and releasing the hydrolytic enzymes.

Term

What is the structure and function of the cytoskeleton?

Definition

Cytoskeleton structure: Composed of microtubules microfilaments, and intermediate filaments.

Function: Supports the cell, maintain its shape, and aids in cell motility.

Term

What is the structure and function of microtubules?

Definition

Microtubules structure: Hollow rods made up of polymerized tubulin radiate throughout the cell and provide it with support.

Function: Provides the framework for organelle movement within the cell.

Term

 

 

What is the structure and function of microfilaments?

Definition

 

Microfilaments structure: Are solid rods of actin.

 

Function: which are important in cell movement as we as support of muscle contraction.  

Microfilaments move materials across the plasma membrane.

Term

 

 

What are the seven ways of cellular transport?

Definition
  1. Simple Diffusion
  2. Facilitated Diffusion
  3. Active transport
  4. Endocytosis
  5. Exocytosis
  6. Intracellular Circulation
  7. Extracellular Circulation
Term

What is simple Diffusion?

Is energy required?

Definition

Simple Diffusion is the net movement of dissolved particles down their concentration gradients- from regions of high to low concentration.

Energy is no required.

Term

What is a type of Simple Diffusion?

Define it.

Definition

Osmosis: The simple diffusion of water from a region of lower solute concentration to a region of higher solute concentration.

Term

What are the three types of osmosis concentration.

Definition

1. Hypertonic: When cytoplasm has a lower solute concentration than the extracellular medium

2. Hypotonic: If the extracellular medium is less concentrated than the cytoplasm of the cell and water will flow into the cell, causing it to lyse *burst*

3. Isotonic: If the cytoplasm has the same solute concentration as the cell's cytoplasm. Water will move back and forth in equal amounts across the cell membrane.

Term

What is facilitated diffusion?

Does it require energy?

Definition

Facilitated diffusion is a type of passive transport. The net movement of dissolved particles down their concentration gradient through special channels or carrier proteins in the cell membrane.

Energy is not required.

Term

What is Active Transport?

Does it require energy?

Definition

Active Transport is the net movement of dissolved particles against their concentration gradient. The carrier molecules or transport proteins aid in the cell's internal content of hte ions and large molecules.

It requires energy.

Term

What are the three types of carrier molecules that facilitate in active transport?

Definition

The passage of specific ions and molecules are facilitated by three types of carrier molecules: symporters, antiporters and pumps.

Term

What is a symporter in active transport?

Definition

Symporter: Move two or more ions or molecules in the same direction across the membrane.

Term

What is antiporters in active transport?

Definition

Antiporters exchange one or more ions (or molecules) for another ion or molecules across the membrane.

Term

What are pumps in active transport?

What is an example?

Definition

Pumps in active transport are energy-dependent carriers (Requires ATP)

Sodium-Potassium Pump

Term

What is structure and function endocytosis?

What are the two types of endocytosis?

Definition

Endocytosis structure: is a process in which the cell membrane invaginates, forming a vesicle that contains extracellular medium.

Function: Allows the cell to bring large volumes of material into the cell.

Types: Pinocytosis and phagocytosis

Term

What is pinocytosis and phagocytosis?

Definition

Pinocytosis: ingestion of fluids or small particles.

phagocytosis: the engulfing of large particles.

Term

What is exocytosis?

Definition

In Excocytosis, a vesicle within the cell fuses with the cell membrane and release a large volume of contents to the outside.

Term

Fusion of the vesicle with the cell membrane can play an important role in _________ and ________

Definition

Fusion of the vesicle with the cell membrane can play an important role in CELL GROWTH & INTERCELLULAR SIGNALING.

Term

What is an example of signaling to neighboring cells?

Definition

Neurotransmitters act as signals to neighboring cells.

Term

What is intracellular circulation?

Definition

Intracellular circulation is the movement within a cell.

Term

What are the three types of intracellular circulation?

Definition

1. Brownian movement

2. Cyclosis or streaming

3. Endoplasmic Reticulum.

Term

What is brownian movement?

(Intracellular movement)

Definition

Brownian movement: kinetic energy spreads small suspended particles throughout the cytoplasm of the cell.

Term

What is cyclosis or streaming?

(Intracellular movement)

Definition

Cyclosis is the circular movement of cytoplasm around the cell tranports molecules.

Term

How do thing move within the cell with the

Endoplasmic Reticulum?

Definition

The ER forms a network of channels throughout the cytoplasm and provides direct continuous passageway from the plasma membrane to the nuclear membrane.

Term

What is extracellular circulation?

Definition

Extracellular circulation is the movement of materials on a larger scale through the body of the organism.

Term

What are two examples of extracellular circulation?

Definition

1. Diffusion

2. Circulatory System

Term

What is the function of diffusion in extracellular circulation?

Definition

Diffusion can transport food and oxygen from the enviornment to cells, if the cells are in direct or close contact with the external environment.

Term

How does the circulatory system deal with movements of materials through the body of an organism?

(Extracellular circulation)

Definition

Circulatory system: When the cells are too far from the external environment to transport materials by diffusion then a circulatory system is needed.

- includes vessels to transport fluid and a pump to drive the circulation.

Term

What is cell division?

Definition

Cell division is when the cell doubles its organelles and cytoplasm, replicates its DNA and divides into two.

Term

In Unicellular organism what does cell division mean?

Definition

Cell division means reproduction in unicellular organisms.

Term

What does cell division mean for a multicellular organism?

Definition

Cell division is a means for growth, development and replacement of worn out cells in multicellular organisms.

Term

What are the two types of courses for cellular division?

Definition

1. Meiosis

2. Mitosis

Term

What precedes mitosis and meiosis?

Definition

Interphase precedes mitosis and meiosis

Term

What is interphase?

How much time does a cell spend in interphase?

Definition

Interphase is the period of growth and chromosome replication. The cell performs its normal cellular function and each choromosome is replicated so that during division a complete copy of the genome is distributed to the daughter cells.

90% of a cell's life is spent in interphase.

Term

During interphase, what happens after replication?

Definition

After replication within interphase, the chromosome consist of two identical sister chromatids held togehter by a central region, the centromere. The individual chromosomes are not visible at this time, the DNA is uncoiled and called chromatin.

Term

What are the 3 stages of interphase?

Definition

1. G1: This phase initiates interphase. Active growth and can vary in length. Cell increase in size & synthesizes proteins. The length of the G1 phase determines the entire length of the entire cell cycle.

2. S: This is the period of DNA synthesis.

3. G2: The cell prepares to divide in G2. IT grows and synthesizes proteins.

Term

What is the last phase of the cell cycle?

Definition

The M Phase is the last phase of the cell cycle which could either be Mitosis or Meiosis, generally resulting in either two identical or 4 non-identical daughter cells.

Term

What is mitosis?

Definition

Mitosis is the division and distribution of the cell's DNA

Term
What type of cell does mitosis take place in?
Definition
Somatic cells.
Term
What is karyokinesis?
Definition
Karyokinesis is nuclear division
Term
What is cytokinesis?
Definition
Cytokinesis is cell division of the cytoplasm.
Term
What are the 5 phases of mitosis?
Definition
1. Prophase
2. Metaphase
3. Anaphase
4. Telophase
5. Cytokinesis
Term
What is prophase?
(Mitosis)
Definition
- Chromosomes condense and the centriole pairs (in animals) separate and move toward the opposite poles of the cell.
- the spindle apparatus forms between them and the nuclear membrane dissolves, allowing the spindle fibers to interact with the chromosomes.
Term
What is metaphase?
Definition
- Centrioles at opposite poles of the cell.
- Fiber spindle attach to each chromatid at the KINETOCHORE on the centromere.
- spindle fibers align the chromosomes at the center of the cell, forming the METAPHASE PLATE.
Term
What is anaphase?
(Mitosis)
Definition
- Centromeres split so that each chromatid has its own distinct centromere, allowing sister chromatids to separate.
- the sister chromatids are pulled towards opposite poles of the cell by shortening the spindle fibers.
Term
What is telophase?
(Mitosis)
Definition
-spindle apparatus disappears.
- nuclear membrane forms around each set of newly formed chromosomes.
- thus each nucleus contains the same number of chromosomes (diploid number, 2N) as the original or parent nucleus.
- chromosomes uncoil, resuming their interphase form.
Term
What is cytokinesis?
(Mitosis)
Definition
- near the end of the telophase the cytoplasm divides into two daughter cells, each with a complete nucleus and its own set of organelles.
- in animal cells, a CLEAVAGE FURROWS forms, and the cell membrane indents along the equator of the cell, eventually pinching through the cell and separating the two nuclei.
- in plant cells a cell plate forms between the two nuclei, effectively splitting the plant cell in half allowing the cell to divide.
Term
What is meiosis?
Definition
Meiosis process of production of sex cells by the fusion of two gametes.
Term
How are mitosis and meiosis similar and different?
Definition
Similar: the cell duplicates its chromosomes before undergoing the process.

Differ: mitosis preserves the diploid number of the cell and meiosis produces haploid (1N) halving the number of the cell.
Term
How many divisions are involved in meiosis?

How many haploid cells are produced?
Definition
- two divisions occur in meiosis

- 4 haploid cells, called gametes
Term
What results in interphase during meiosis?
Definition
- Interphase in meiosis is similar to mitosis, the parent's cell chromosomes are replicated during interphase, giving 2N number of sister chromatids.
Term
What are the 5 phases of meiosis?
Definition
1. Prophase I.
2. Metaphase I.
3. Anaphase I.
4. Telophase I.
5. Second meiotic division
Term
What is prophase I?
(Meiosis)

Reference: synapsids, tetrad & crossing over.
Definition
- Chromatin condenses into chromosomes, spindle apparatus forms, and the nucleoli and nuclear membrane disappear.
- homologous chromosomes come together and intertwine in a process called synopsis. tetrad: each synaptic pair of homologous chromosome contains 4 chromatids.
- Crossing over: sometimes chromatid of homologous chromosomes break at corresponding points (Chiasmata) and exchange equivalent pieces of DNA.
Term
Does crossing over produce genetic variation?
Definition
Crossing over does not produce genetic variation because it occurs between homologous chromosomes.
Term
What is recombination?
Definition
Recombination among chromosomes results in increased genetic diversity within a species.
Term
What occurs during metaphase I?
(Meiosis)
Definition
Homologous pairs (tetrads) align at the equatorial plane and each pair attaches to a separate fiber at the kinetochore.
Term
What occurs during Anaphase I?
(meiosis)
Definition
- The homologous pairs separate are pulled to opposite poles of the cell, process called DYSJUNCTION.
-
Term
What is dysjunction?
(meiosis: Anaphase I)
Definition
- each chromosome of paternal origin separates from Its homologous of maternal origin, and either chromosome can end up in either daughter cell.
- the distribution of homologous chromosomes to the two intermediate cells is random with respect to parental origin.
- each daughter cell will have a unique pool of genes from a random mixture of maternal and paternal origin.
Term
What is nondysjunction?
Definition
Nondysjunction occurs when cells do not separate appropriately during meiosis.
Term
What is telophase I?
(Meiosis)
Definition
- a nuclear membrane forms around each new nucleus.
- each chromosome still consists of sister chromatids joined at the centeomere
Term
What is the second meiotic division?
Definition
- similar to mitosis except that meiosis II isn't preceded by chromosomal replication.
- the chromosomes align at the equator, separate and move to opposite poles and are surrounded by a re-formed nuclear membrane.
- the new cells have the haploid number of Chromosomes.

note: in women only 1 of the daughter cells becomes a functional gamete; the other two or three are destroyed by the body
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