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Gastrointestinal Molecules
Physiology
13
Medical
Graduate
01/17/2011

Additional Medical Flashcards

 


 

Cards

Term

Gastrin

(Hormone)

Definition

Stimulates - Acid Secretion, Growth of Mucosa

 

Site of Release - Antrum

 

Releasers - Peptides, Amino Acids, Distension, Vagus Nerve

Term

Cholecystokinin (CCK)

(Hormone)

Definition

Simulates - Gallbladder Contraction, Pancreatic Enzyme & Bicarbonate Secretion, Growth of Exocrine Pancreas

 

Inhibits - Gastric Emptying

 

Site of Release - Duodenum, Jejunum

 

Releasers - Peptides, Amino Acids, Fatty Acids > 8 carbons, Acid

Term

Secretin

(Hormone)

Definition

Simulates - Pancreatic & Biliary Bicarbonate Secretion, Growth of Exocrine Pancreas, Pepsin Secretion

 

Inhibits - Gastric Acid Secretion, Trophic effect of Gastrin

 

Site of Release - Duodenum

 

Releasers - Acid, Fat

 

Term

Gastric Inhibitory Peptide (GIP)

(Hormone)

Definition

Stimulates - Insulin Release


Inhibits - Acid Secretion


Site of Release - Duodenum, Jejunum


Releasers - Glucose, Amino Acids, Fatty Acids

Term

Motilin

(Hormone)

Definition

Stimulates - Gastric & Intestinal Motility

 

Site of Release - Duodenum, Jejunum

 

Releasers - Nerve Stimulation

 

Term

Pancreatic Polypeptide

(Candidate Hormone)

Definition

Releasers - Protein, Fat, Glucose

 

Actions - Decrease Pancreatic Bicarbonate and Enzyme Secretion

Term

Peptide yy

(Candidate Hormone)

Definition

Releasers - Fat

 

Actions - Decrease Gastric Secretion & Emptying

Term

Enteroglucagon

(Candidate Hormone)

Definition

Releasers - Hexose, Fat

 

Actions - Decrease Gastric Secretion & Emptying, Increase Insulin Release

Term

Vasoactive Intestinal Peptide (VIP)

(Neurocrine)

Definition

Site of Release - GI Tract Mucosa & Smooth Muscle

 

Actions - Relaxes sphincters, Relaxes gut circular muscle, Simulates Intestinal & Pancreatic Secretion

Term

Bombesin or Gastric Releasing Peptide (GRP)

(Neurocrine)

Definition

Site of Release - Gastric Mucosa

 

Actions - Stimulates Gastrin Release

Term

Enkephalins

(Neurocrine)

Definition

Site of Release - GI Tract Mucosa & Smooth Muscle

 

Actions - Stimulates Smooth Muscle Contraction, Inhibits Intestinal Secretion

Term

Somatostatin

(Paracrine)

Definition

Actions - Inhibits Gastrin release, Peptide Hormone release, Acid secretion

 

Site of Release - GI mucosa, Pancreatic Islets

 

Releasers - Acid(pH<3), (Vagus Inhibits Release)

Term

Histamine

(Paracrine)

Definition

Actions - Stimulates Acid Secretion

 

Site of Release - Oxyntic gland mucosa/ECL Cell

 

Releasers - Gastrin, Acetylcholine

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