Term
| Which fungal infections are characterized by a splendore hoeppli asteroid body? |
|
Definition
| sporotrichosis, coccioidomycoses, aspergillosis, candidiasis, mycetoma |
|
|
Term
| What subcutaneous mycosis can also present as plaques? |
|
Definition
|
|
Term
| What type of fungi is likely to cause systemic mycosis? |
|
Definition
| Thermally dimorphic fungi, among others |
|
|
Term
| Where is blastomyces usually found (in environment)? |
|
Definition
| Dead/decaying organic matter/leaf litter |
|
|
Term
| What is the only yeast w/ broad based buds? |
|
Definition
|
|
Term
| Does blastomyces spread person-person? |
|
Definition
| NOOOOOOO!!!!!! thermal dimorphs usually don't - they're often in a granuloma and not terribly transmissible |
|
|
Term
|
Definition
1ary: flu-like, with patchy lobar infiltrates
chronic: TB-like
2ary: systemic-> liver, spleen, prostate, UG, brain |
|
|
Term
| Which of the coccidioides is found only in Cali? |
|
Definition
|
|
Term
| Which fungi is characterized by spherules filled with endospores? |
|
Definition
|
|
Term
| What environments are associated with h. capsulatum? |
|
Definition
| Bird/bat guano enriched soils, old buildings, bird roosts, caves |
|
|
Term
| What are symptoms of disseminated histoplasmosis? |
|
Definition
| Weight loss, fatigue, oropharyngeal ulcers, hepatosplenomegaly, bone marrow lesions, adrenal insufficiency, meningitis: REALLY SERIOUS, though acute histoplasmosis is self-limiting + flu-like |
|
|
Term
| Which h. capsulatum should you use serum tests to diagnose? Culture? |
|
Definition
| For non-disseminated, use serum; for invasive, use culture |
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|
Term
| Which thermally dimorphic yeast will you always find intracellularly in the yeast form? |
|
Definition
|
|
Term
| What is the only intracellular thermal dimorph? |
|
Definition
|
|
Term
| What is the main thermal dimorph of s. america? |
|
Definition
|
|
Term
| Which fungi are resistant to voricanazole? |
|
Definition
| Zygomycota (mucor, rhizopus), Sporothrix schenckii, paracoccidioides, Candida glabrata, cryptococcus |
|
|
Term
|
Definition
| Part of normal flora - endogenous infection (overgrowth of flora -> infection) possible. Also exogenous, either from contaminated object or from a person. |
|
|
Term
| What is the most common infective Candida sp.? |
|
Definition
|
|
Term
| What is the most common disease involving the CNS? |
|
Definition
|
|
Term
| What sort of soil is particularly likely to harbor cryptococcus? |
|
Definition
| Enriched by pigeon droppings |
|
|
Term
| What are 3 characteristics of cryptococcus that distinguishes it from other yeasts? |
|
Definition
1) melanin production (-> birdseed/niger)
2) variable size
3) capsule |
|
|
Term
| What is a particularly angioinvasive opportunistic fungus? |
|
Definition
|
|
Term
| What is the most common opportunistic pathogen of AIDS patients with low CD4? |
|
Definition
|
|
Term
| What are characteristic morphologies of pneumocystis? |
|
Definition
cysts, trophozoites, sporocysts - NO BUDDING
(cannot be cultured) |
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