prednisone

(Deltasone)

corticosteroid

moniter for hypokalemia and hyperglycemia

do not d/c after long term use-adrenal crisis

notify HCP if pregnant

long term complications

weakens skin/changes deposition of fat

ketoconazole

(Nizoral)

antifungal

coadministration may cause fatal cardiac arrythmias

hepatic disease

monitor for hepatotoxicity

notify of GI symptoms, signs of liver disease (fatigue, nausea, anorexia, vominting, dark urine, pale stools)

possible long-term therapy

OTC as lotion, shampoo, cream

scabicide/pediculicide-scabies, lice, nits

NOT FIRST LINE DUE TO BRAIN/NERVOUS SYSTEM TOXICITY

Premature neonate, inflammation of skin, abrasions of skin, seizure disorder

Implementation:

Apply to body areas and scalp

No face or mucous membranes

Wear gloves to apply, then thoroughly wash hands

lotion 0.5%

prescription-kills lice and some lice eggs

Not approved by the FDA for pubic lice

binds calcium channels in CNS tissues

decreased seizure activity, decreased neuropathic pain

do not stop abruptly, give no regard to meals, may cause dizziness, assess for seizures, pain, and mental status

avoid alcohol

HIGH ALERT MED

inhibits ascending pain pathways in CNS, increases pain threshold, alters pain perception

opiate analgesic

Waring: may cause resp depression (hold for RR <10) and substance abuse

may cause nausea and constipation.

Taper to stop.

May cause withdrawls

Controlled substance: Must be counted

etanercept (Enbrel)

Antirheumatic agen (DMARDS)

BBW: infection, lymphoma, neoplastic disease

subQ injection

may self inject, thigh, abdomen, upper arm, must rotate locations 

Bone reabsorption inhibitor

BBW: women with active/history of venous thrombosis; stroke

Teach pt to discontinue 72 hrs b4 prolonged bedrest and report swelling, warmth, or pain in calves

regulates production of neutrophils in bone marrow

hematopoeitic agent

increases phagocytic ability and decreases rate of infection

may cause bone pain, monitor bone counts

beware of fever/chills

stimulates division and differentiation of RBCs in bone marrow

antianemic

induces erythmopoiesis

often post-chemo

BBW: serioius cardio events/thrombolitic events

monitor blood counts, bp before and after therapy

report severe headache to provider

-inhibits activityof HIV-1 reverse transcripase

-antiretroviral

-interupts HIV replication, slows progression of HIV infections

-used to treat HIV in combination with other antiretroviral agents

-interacts with many drugs and herbs, must check meds and supplements before starting

-serious adverse psychiatric experiences in 50% of patients

-baseline psyche eval needed

-does not reduce risk of HIV to others

emtricitabine (Emtriva/Truvada)

similar to Efavirenz

use to treat HIV with at least 2 other antiretroviral agents

BBW: lactic acidosis & hepatomegaly with fatty liver

obtain baseline blood counts with LFT's (liver function tests)

may cause redistribution of body fat

report jaundice

does not reduce risk of HIV to others

Vasodialator

angiotension II receptor antagonist

hypertension & heart filure

no pregnant

monitor BP, if falls lay supine/flat

blocks beta-andregenic receptors/decreases O2 requirements

anti anginal, antihypertensive

slow heart rate/reduce cardiac output/reduce BP/ decreases myocarial ischemia severity

treats angina and hypertension

monitor BP and pulse-not for pulse under 60 or systolic BP under 90