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Fundamentals-Pharm
Autonomic Pharmacology
4
Pharmacology
Graduate
02/17/2011
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Term
Which post-ganglionic Sympathetic neurons do not use norepinephrine
 Definition

Adrenal medulla

Sweat Glands

Renal Vasculature
Term
What are the post-ganglionic receptors for the Autonomic NS
 Definition
Nicotinic
Term

What are the major types of cholinergic receptors?

How are they different?

 Definition

Nicotinic

Ligand Gated Ion-channels

Muscle or Neuronal types

Muscarinic

G-protein Coupled

M1: Nerve

M2: Heart, SM(AC block, Increase K)

M3: Gland, SM, Endocrine(PLC)

 
Term
What are the smpathetic receptors important for the eye, lung, heart, and blood vessels
 Definition

Eye

Alpha-Mydriasis

Beta-Increase aqueous humor, block-> decrease

Muscarinic-Miosis, Ciliary contract(aqueous outflow)

Bronchioles

B-Dialation

Muscarinic-Contraction

Blood Vessels

Alpha 1- Contraction(HPTN), Block-reverse

Beta 2- Skeletal BV relaxation

Alpha 2-decrease

Heart

Beta 1- Inotropy, HR

Muscarinic M2- Decrease Inotropy, HR
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