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Fundamentals of Cell Biology: Ch. 1-3
Covering the basics of biology
90
Biology
Undergraduate 1
09/06/2010

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Cards

Term
Biology
Definition
the scientific study of all living things
Term

living things

 

Definition
all the organisms descending from a single-celled ancestor
Term

Characteristics of living organisms:

(Seven of them)

Definition

- consist of one or more cells

- contain genetic information

- genetically related and have evolved

- can convert molecules from their environment into new biological molecules

- can extract energy from the environment and use it for biological work

- can regulate their internal environment

Term

Evolution

 

Definition

a central theme: living systems evolve through differential survival and reproduction

 

Term

unicelluar

 

Definition
a single cell carries out all functions of life
Term

multicellular

 

Definition

made of many cells that are specialized for different functions

 

Term

Cell Theory:

(Six points)

Definition

- cells are the basic structural and physiological units of life

- cells are both distinct entities and building blocks of more complex organisms

- all cells come from pre-existing cells

- all cells are similar in chemical comp. 

- most of the chemical reactions of life occur within cells

- complete sets of genetic info. are replicated and passed during cell division

Term

Schleiden and Schwann

 

 

Definition
In 1838, they proposed that cells and building blocks of more complex organisms
Term
species
Definition
a group of organisms that look similar and can breed successfully with one another
Term

adaption

 

Definition
traits that increase survival will move onto further generations
Term
DNA
Definition

deoxyribose nucleic acid: genetic info. passed from parent to daughter cells

 

Term
genome
Definition

sum total of all DNA in a cell

- all cells in multicellular organisms have the same genome unless an abnormality occurs

Term
nucleotides
Definition
the sequence of these represents DNA
Term
gene
Definition

a specific segment of DNA

- contains info. to make proteins

- mutations occur in the sequence

Term

Life chain:

(11 steps)

Definition
atoms--molecules--cells--tissues--organs--organ systems--organism--population--community--ecosystem--biosphere
Term
prokaryotes
Definition

single-celled organisms

- located in oceans, protected from UV radiation

Term
metabolism
Definition
the sum of all chemical reactions that occur in cells
Term
photosynthesis
Definition

formation of a carbohydrate using sunlight, water, and CO2

- led to formation of ozone layer and O2 in atmosphere

Term
eukayrotic
Definition
cells evolved from prokaryotes 
Term
organelles
Definition
membrane-bound compartments with specialized functions
Term
binomial
Definition

the naming process:

Genus species

Homo sapien

Term
The 3 domains:
Definition
1) Bacteria 2) Archaea 3) Eukarya
Term
autotrophs
Definition
capable of photosynthesis; producers
Term
heterotrophs
Definition
require a source synthesized by other organisms; consumers
Term

Scientific Method:

( 5 Steps)

Definition

- Observations

- Questions

- Hypothesis

- Predictions

- Experimentation

Term

inductive logic

 

Definition
based on principles
Term
deductive logic
Definition
based on predictions
Term
atomic mass number
Definition
sum of protons and neutrons 
Term
element
Definition
pure substance containing only one kind of atom
Term
atomic number
Definition
number of protons
Term
isotopes
Definition
form of an element with different numbers of neutrons, thus different mass numbers
Term
atomic weight
Definition
average number of mass numbers of isotopes in their normally occurring proportions
Term
radioisotopes
Definition

unstable and give off energy in the form of radiation from the nucleus 

- decay transforms atoms

 

Term
orbitals
Definition

describe location of electrons in atom

- where the electron is 90% of the time

Term
electron shell
Definition

where orbitals occur in series

- also known as energy levels

Term
molecules
Definition
atoms can share electrons or lose or gain electrons, resulting in atoms bonded together
Term
octet rule
Definition
complete outer energy level 
Term
chemical bond
Definition
attractive force that links atoms to form molecules
Term
covalent bond
Definition

atoms share one or more pairs of electrons

- very strong bond

Term
compound
Definition
a molecule made up of two or more elements
Term
molecular weight
Definition
sum of the the atomic weights of all the atoms in the molecule
Term
electronegativity
Definition
the attractive force that an atomic nucleus exerts on electrons
Term
non-polar covalent bond
Definition

two atoms have similar electronegativity

- electrons shared equally

Term

polar covalent bond

 

Definition

one atom has more electronegativity 

- electrons drawn to nucleus

- not shared equally

Term
ions
Definition
electrically charged particles; when atoms lose or gain electrons
Term
cations
Definition
positive ion
Term
anion
Definition
negative ion
Term
ionic bonds
Definition
formed by the electrical attraction of positive and negative ions
Term
hydrogen bonds
Definition
attraction between the negative end of one molecule and the positive hydrogen end of another molecule
Term
hydrophylic 
Definition
"water-loving"; polar bonds that form hydrogen bonds with water
Term
hydrophobic
Definition
"water-hating"; non-polar molecules that interact with each other but not with water
Term
Van der Waals forces
Definition

attractions between non-polar molecules

- individual interactions are brief and weak but add up to a substantial amount

Term
chemical reactions
Definition

atoms bond or change bonding partners

- matter is neither created nor destroyed

Term
energy
Definition

capacity to do work

- usually changes form during chemical reactions

Term
water
Definition

unique structure and special properties 

- polar molecule that forms hydrogen bonds

Term
specific heat
Definition
amount of energy necessary to raise the temp. of 1 g or water by 1* C
Term
cohesion
Definition

water molecules resist coming apart from one another

- helps water move through plants

- results in surface tension

Term
solution
Definition
when you combine a substance (solute) and dissolved in a liquid (solvent)
Term
mole
Definition

amount of a substance (in grams); the mass of which is numerically equal to its molecular weight

- 6.02 x 10^23 molecules

Term
pH
Definition

negative log of the molar concentration of H+ ions

- the lower the pH, the more acidic the solution

Term
buffer
Definition

a weak acid and its corresponding base

- helps maintain pH

Term
isomer
Definition
molecule with the same chemical formula but with the atoms arranged differently
Term
structural isomers
Definition
differ in how atoms are joined
Term
macromolecules
Definition

-proteins

- nucleic acids

- carbohydrates

- lipids

Term
condensation reactions
Definition
where polymers are formed by covalent bonds and removed by dehydration bonds
Term
Functions of proteins:
Definition

- structural support

- regulation

- movement

- defense

- catalyst

- protection

- transport

Term
amino acids
Definition

what make up proteins

- essential amino acids: what the body can't produce on its own

- 20 total amino acids

[image]

Term
peptide bond
Definition

covalently bonded amino acids together

- forms polypeptide chain

 

Term
primary structure
Definition

sequence of amino acids in a protein

- determines secondary structure and tertiary structure (how it folds)

 

Term
secondary structure
Definition

Helix: right-handed coil from hydrogen bonding

Pleated Sheet: two or more polypeptide chains are aligned

Term
tertiary structure
Definition

bending and folding results in a macromolecule with a specific 3D shape

- affected by high temps., pH changes, and high concentrations of polar molecules

Term
denaturation
Definition
loss of 3D structure and thus function of the protein 
Term
chaperonins
Definition
proteins that help prevent the misfolding of proteins
Term
carbohydrates
Definition

molecules in which carbon is flanked by hydrogen and hydroxyl groups

H--C--OH

 

Term

Functions of carbs:

(two)

Definition

- energy source

- carbon skeletons for many other molecules

Term
monosaccharides
Definition
simple sugars
Term
polysaccharides
Definition

hundreds of monosaccharides 

- starch, glycogen

Term
glucose
Definition

monosaccharide; used by cells as energy source 

- usually exists as a strong ring

Term
glycosidic linkages
Definition
monosaccharides bind together in condensation reactions
Term
starch
Definition
polysaccharide that acts as the storage of glucose in plants
Term
glycogen
Definition
polysaccharide that acts as the storage of glucose in animals
Term
cellulose
Definition
polysaccharide that is very stable and good for structural support
Term
lipids
Definition

nonpolar hydrocarbons

* serve as insulation in animals, repel water, prevent drying

- fats and oils: energy storage

- phospholipids: cell membranes

- cartenoids

 - steroids

Term
triglycerides
Definition

simple lipids

- made of 3 fatty acids and 1 glycerol

Term
saturated
Definition

no double bonds between carbons; saturated with hydrogen atoms

- typically animals fat, packed tightly, solid at room temp.

Term
unsaturated
Definition

some double bonds with carbons

- typically plant oils, kinks prevent packing, liquid at room temp.

 

Term
phospholipid
Definition

fatty acids bound together to glycerol, a phosphate group replaces one fatty acid 

- phosphate group is hydrophylic and polar

[image]

Term
nucleic acids
Definition

DNA: deoxyribose nucleic acid

RNA: ribose nucleic acid

Term
nucleotides
Definition

- consist of a pentose sugar (5 carbon), a phosphate group, and a nitrogen-containing base

[image]

Term
nucleotides and pairings:
Definition

adenine -- thymine

guanine -- cytosine

- uracil replaces thymine in RNA

- purines pair w/ pyrimidines by hydrogen bonding

- folded RNA can act as a catalyst- ribozyme

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