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freshman Bio Test 4
Mitosis, Meiosis, and genetics
80
Biology
Undergraduate 1
11/06/2008

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Term
Autosome
Definition
Non-sex chromosomes (#1-22)
Term
Heterozygous
Definition
Different trait on each chromosome. (Tt, Aa)
Term
Homozygous
Definition
Same trait on each chromosome. (AA,aa)
Term
Locus
Definition
Location of a gene on a chromosome.
Term
Dominant Trait
Definition
A trait in a heterozygous pair that shows in the phenotype. Overrides a recessive trait.
Term
Recessive trait
Definition
A trait that is overriden by the presence of a dominant trait.
Term
Monohybrid cross
Definition
Breeding with a single specific trait in mind.
Term
Dihybrid cross
Definition
Breeding with two specific traits in mind.
Term
Genotype
Definition
The actual genetic makeup.
Term
Phenotype
Definition
How the traits appeat when observed.
Term
Test Cross
Definition
Crossing an unknown genome with a homozygous recessive in order to determine the unknown genotype.
Term
Autosomal Abnormalities
Definition
Diseases, either dominant or recessive that are carried on the non-sex chromosomes. Affect males and females equally.
Term
Incomplete Dominance
Definition
No dominant or recessive trait. Phenotype shows genotype directly. (Red + white = pink)
Term
What are the stages of the Cell Cycle?
Definition
Interphase (G1, S, G2), Mitosis/Meiosis.
Term
Interphase
Definition
The "resting" part of the cell cycle. Time between divisions.
Term
What occurs during the g1 part of the cell Cycle?
Definition
Growth, replenishing of organelles. (Accumulates materials)
Term
What occurs during the S portion of cell cycle?
Definition
Synthesis of DNA
Term
What happens during the G2 stage of interphase?
Definition
The cell creates proteins necessiary for cell division.
Term
Chromatid
Definition
Half of an X shaped chromosome. One of each chromatid goes to each cell during Mitosis.
Term
When is Meiosis used?
Definition
In sex cells only. To create gametes.
Term
Karyokinesis
Definition
Division of the nucleus.
Term
Cytokinesis
Definition
Divsion of the cytoplasm.
Term
Difference between Plant and Animal Cytokinesis
Definition
In plant Cytokinesis a cell plate is formed to divide the cells.
Term
Apoptosis
Definition
Programmed cell death. Happens at any of the checkpoints during cell cycle if a problem cannot be repaired.
Term
Cyclins
Definition
Signal for the cell to switch from one portion of interphase to another.
Term
Chromatin
Definition
Loosely arranged DNA
Term
Diploid
Definition
Having two sets of Chromosomes, most advanced life forms are diploids.
Term
Haploid
Definition
Having one set of chromosomes, most notable sex cells.
Term
Stem cells
Definition
Cells with the capacity to grow where needed. Mainly found in the spine.
Term
Neoplasm
Definition
Abnormal growth of cells.
Term
Malignant
Definition
Cancerous
Term
Benign
Definition
Not cancerous.
Term
Carcinogenic/carcinogenesis
Definition
Cancerous/development of cancer
Term
Tumor
Definition
Cells bind together due to a lack of contact inhibior.
Term
Metastasis
Definition
Cancerous cells spread through the bloodstream causeing the cancer to spread.
Term
Angiogenesis
Definition
Creation of blood vessels to provide nutrients to tumors.
Term
Oncogenes
Definition
Proto-Oncogenes promote the cell cycle in various ways. If that mutates, may lose control and become an oncogene.
Term
Tumor Suppressor genes
Definition
Cause cells to stop reproducing when they are too close together. If mutated can cause tumors.
Term
Proto-Oncogenes
Definition
Promote the cell cycle in various ways.
Term
Centrosome
Definition
Form the microtubules used to align and seperate chromosomes.
Term
Kinetochore
Definition
The microtubules that attach to chromosomes to pull them apart.
Term
Cell Plate
Definition
Formed in a plant cell during cytokinesis to separate the cells.
Term
Telomere
Definition
The ends of a chromosome, get shorter with every reproduction and cause aging.
Term
Spindle Fibers
Definition
Term
Where are the checkpoints for the cell cycle?
Definition
M checkpoint, G1 checkpoint, G2 checkpoint
Term
M checkpoint
Definition
Apoptosis occurs if chromosomes are not properly aligned for division
Term
G1 checkpoint
Definition
Apoptosis occurs if DNA is damaged and cannot be repaired
Term
G2 checkpoint
Definition
Apoptosis occurs if DNA is damaged or incomplete.
Term
What are the stages of Mitosis?
Definition
Prophase, Metaphase, Anaphase, Telophase
Term
what occurs during Prophase?
Definition
Nuclear envelope disappears, Nucleolus disappears, Centromeres move to the poles and spindles begin to take shape.
Term
Allele
Definition
Different forms of the same gene
Term
Homologous Chromosomes
Definition
Chromosomes that are in the same position and stain the same (effectively the same chromosome from two different people with different traits)
Term
Fertilization
Definition
Process of a sperm fertilizing and egg.
Term
Zygote
Definition
Pre-embryonic stage after a sperm and egg join.
Term
Gametes
Definition
sex cells
Term
What are the properties of cancer cells?
Definition
May have oncogenes or mutations in the tumor inhibitors. They are not organized,and have an abnormal nucleus.
Term
What protein triggers apoptosis?
Definition
P53
Term
Result of Mitosis
Definition
Two daughter cells each with the same number of chromosomes as the mother cell
Term
Telophase
Definition
Spindle disappears, one of each daughter chromosome present at each pole, nuclear envelope and nucleolus reappear.
Term
Anaphase
Definition
centromere dissolves, sister chromatids separate (now called daughter chromosomes), pulled to opposite poles along kinetocore fibers
Term
Metaphase
Definition
Kinetochore fibers attach to chromosomes and align them on the metaphase plate
Term
Crossing over
Definition
Occurs during Prophase 1 of Miosis genetic materical is traded between two homologous chromosomes
Term
Recombination
Definition
Exchange of genetic material during Prophase 1
Term
Genetic variation
Definition
Offspring are not identical to either parent due to the crossover of genetic material during meiosis
Term
Interkinesis
Definition
The resting point between Meiosis 1and meiosis 2
Term
Stages of Miosis
Definition
Prophase 1, Metaphase 1, Anaphase 1, Telophase 1, & 2 (for all)
Term
Prophase 1
Definition
same as mitosis except: chromosomes align together (on top of each other), synoptenemal complex attaches chromosomes, which wind and share their genetic material
Term
chiasmata
Definition
places where chromosomes cross over
Term
Polar Body
Definition
3 of the 4 cells created during oogenesis. These cells give their cytoplasm to the main egg cell.
Term
Reduction Division
Definition
(Meiosis 1?)
Term
equatorial division
Definition
(Meiosis 2?)
Term
All second phases in Meiosis are the same as...
Definition
Mitosis
Term
Spermatogenesis
Definition
Creation of sperm
Term
oogenesis
Definition
Creation of an egg cell.
Term
Synoptenemal Complex
Definition
Attaches chromosomes during Prophase 1 of Meiosis
Term
Significance of Meiosis
Definition
It allows genetic variation in reproduction. Only occurs in sex cells.
Term
Difference between meiosis and mitosis
Definition
Meiosis creates haploid sex cells be dividing the number of sex cells
Term
Significance of genetic variation
Definition
Allows for natural selection. Allows people to adapt.
Term
significance of prophase 1 and crossing over in meiosis
Definition
Allows for genetic variation
Term
Differences between spermatogenesis and oogenesis
Definition
Spermatogenesis creates 4 sperm with little cytoplasm. Oogenesis creates 1 egg with a lot of cytoplasm.
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