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Final
lecture 2
26
Computer Networking
Undergraduate 4
12/01/2012

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Cards

Term
what 2 non drug therapies are used for SLE
Definition
smoking cessation
sun protection
Term
what are the 4 classes of drug therapies
Definition
NSAIDS
antimalarials
corticosteroids
cytotoxic
Term
4 uses for NSAIDS
Definition
fever, arthritis, serositis, rash
Term
what function might NSAIDS decrease
Definition
renal - but not lupous nephritis
Term
when do you use antimalarials
Definition
cutaneos
arthalgia
fever
fatigue
Term
what is the long term treatment
Definition
antimalarials
Term
dosing for hydroxycholorquine
Definition
200-400 mg/day
Term
dosing for choloroquine
Definition
250-500 mg/day
Term
what is the key monitoring for antimalarials
Definition
eye exams
Term
at what 2 times do you use steroids
Definition
serious clinical manisfestation
unresponsive to other meds
Term
dosing for steroids for:
mild
Definition
10-20 mg/day
Term
dosing for steroids for severe
Definition
1-2 mg/kg
Term
what is the pulse therapy
Definition
large dose if IV methylprednisolone
then oral prednisone
Term
what is the dose of IV methylprednisolone
Definition
500-1000 mg x 3-6 days
Term
oral dose of prednisone
Definition
1-1.5 mg/kg
Term
if using steroids want to remember prophylaxis for
Definition
osteoporosis
Term
cyclophosphamide dose
Definition
50-150 mg/day
Term
how often do you do cyclophosamide doing Qmonth, and then how long Q3 months
Definition
6 monnths,
2 years
Term
for cylcophosamide, WBC must be above
Definition
1500
Term
azothiopurine or cylcophosamide is more toxic
Definition
cyclo
Term
which cytotoxic agent is used for induciton of remission?
which is used for maintenance?
Definition
cyclophosmaide
azothiopurine
Term
what drugs are major cause of drug induced SLE
Definition
hydralazine
procainamide
Term
SLE vs Drug induced:
which occurs at older age
Definition
drug induced
Term
gender domiancne of drug SLE
Definition
none
Term
most common symptom of drug induced SLE
Definition
musculoskeletal
Term
what drug class can be used for drug induced SLE
Definition
NSAIDs
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