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Final Exam: Section 3
Limbic Circuitry
42
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Undergraduate 3
12/15/2015

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Term
Limbic structures mediate the emotional life of an organism, including _____, ______, & _____
Definition
emotional experience, emotional expression, & emotional memory
Term
______ include cognitive evaluation of the nature of a stimulus, prior experience from memory, conscious awareness of the internal & external state of the body, & reactions that can be a mix of skeletal, autonomic, & endocrine responses
Definition
emotions
Term
The term "limbic" was first used by Paul Broca in 1878 to describe the manner in which _____, ______, & ______ (entorhinal) cortices formed an inner border surrounding the subcortical structures in all mammals
Definition
orbitofrontal, cingulate, & parahippocampal
Term
The oldest cortical region, ______, has been associated with olfaction & contributes significantly to survival behavior
Definition
paleocortex
Term
The hippocampus (______) contributes to behavior through an organism's ability to learn & remember significant events
Definition
archicortex
Term
The allocortex structures have ____ layers
Definition
three
Term
Transitional cortical structures (______) are five-layered & can either be peri-allocortex or pro-isocortex
Definition
mesocortex
Term
The newest cortical areas (_____) have fully developed six layers
Definition
isocortex
Term
The _____ is not a key regulator of the hypothalamus, although it does provide important contextual information to emotional experience
Definition
hippocampus
Term
The fact that mammillary bodies & anterior thalamus are often damaged in ______ indicates the role of these structures in memory formation
Definition
Korsakoff's amnesia
Term
Visual agnosias, hypersexuality, hyperorality, emotional blunting/placidity, & willingness to approach previously fear-evoking stimuli are symptoms of ______
Definition
Kluver-Bucy syndrome
Term
The ______ is important in emotional blunting & loss of fear
Definition
amygdala
Term
The amygdala is a ______ structure deep within the temporal lobe
Definition
quasi-cortical
Term
The _____ (not the hypothalamus) is the key regulator of the hypothalamus
Definition
amygdala
Term
Through plasticity in its circuits, the amygdala is essential for ______ of emotions, particularly fear
Definition
conditioned learning
Term
The amygdala receives sensory information from the cortex & thalamus into its ______
Definition
lateral nucleus
Term
The output of the amygdala arises mainly from the ______ & targets primarily the hypothalamus & brainstem
Definition
central nucleus
Term
Amygdala efferents include the ______ to regulate skeletomotor behaviors & the ______ to regulate autonomic & endocrine responses
Definition
periaqueductal gray; lateral & paraventricular hypothalamus
Term
Certain sensory stimuli reach the amygdala directly by way of the ______ before being routed through the cortex
Definition
thalamus
Term
The ______ evokes emotional responses from the amygdala before the cortex can process the sensory information
Definition
low road
Term
The _____ drives more appropriate emotional responses but takes more time for sensory processing
Definition
high road
Term
Anxiety disorders, panic attacks, & phobias are examples of ______ that rise even in the absence of clear triggers
Definition
maladaptive emotions
Term
_______ ultimately give rise to feelings of inadequacy
Definition
cognitive distortions
Term
The ability of cognitive reasoning to correct & reverse maladaptive emotions is the basis for ______
Definition
cognitive behavioral therapy
Term
Ventromedial & orbital divisions of the ______ can suppress emotional expression by inhibiting amygdala output
Definition
prefrontal cortex
Term
The prefrontal cortex is necessary for ______ of emotional memories like fear conditioning
Definition
extinction
Term
There is reduced blood flow in orbitofrontal & cingulate regions in _______ disorder which correlates with reduced gray matter volume in these regions
Definition
major depressive disorder
Term
The ______ helps to guide behavior based on past rewards & punishments
Definition
orbitofrontal cortex
Term
Damage to the ______ is associated with blunted or inappropriate emotions & poor judgment often due to failure to inhibit maladaptive responses
Definition
orbitofrontal cortex
Term
The cingulate gyrus lies immediately above the ______
Definition
corpus callosum
Term
The cingulate gyrus is _______ (stimulate alters autonomic function)
Definition
visceromotor
Term
The cingulate gyrus is a major area involved in the conscious perception of _____
Definition
pain
Term
Septal lesions alter _______ & ______ behaviors
Definition
aggressive & sexual
Term
The _____ is the ventral extension of the striatum (ventral striatum)
Definition
nucleus accumbens
Term
The nucleus accumbens is a ______ interface
Definition
limbic-motor
Term
The nucleus accumbens processes limbic cortical input & provides adaptive motor strategies for ______ behaviors
Definition
motivated
Term
Visceral sensory input to the hypothalamus & amygdala arises from the _____
Definition
nucleus of the solitary tract
Term
_______ input derives from association cortices to the amygdala, hippocampal region, cingulate, & prefrontal cortices
Definition
multimodal processed sensory
Term
______ output originates from the hypothalamus & amygdala to brainstem autonomic centers
Definition
visceral motor
Term
______ output comes from the prefrontal to premotor cortex
Definition
somatic motor
Term
Somatic motor output is relayed through the basal ganglia ______ (the limbic-motor interface that provides adaptive strategies for motivated behaviors)
Definition
nucleus accumbens
Term
All structures within limbic circuitry receive abundant input from brainstem & forebrain _______ systems, which critically modulate emotional behaviors
Definition
monoamine
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