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Final Exam Maxwell BIOS
Ohio U BIOS 1030
109
Biology
Undergraduate 1
12/06/2015

Additional Biology Flashcards

 


 

Cards

Term
What evidence is used to understand evolution?
Definition

Fossils

Embryology

Molecular - DNA and protein sequences

Compartive anatomy - homologous structures

(example of compartive anatomy) Vertebrae forearms 

Term

Name the evidence of evolution:

 

bones used to look at previously living species

Definition
fossils
Term

Name the evidence of evolution:

 

Looking at embryos to compare similar features

Definition
embryology
Term

Name the evidence of evolution:

 

Looking at how DNA and proteins evolve over time and between species

Definition
Molecular evidence
Term

Name the evidence of evolution:

 

comparing anatomy of living animals. Comparing features that evolved from a common ancestor and may have similar or different function in different species

Definition
Comparative anatomy - homologous structures
Term

Name the evidence of evolution:

 

Comparing anatomy of living animals. Structures that evolved seperately but perform similar function

Definition
Comparative anatomy - analogous structures
Term

Name the primate:

 

Larger than monkeys, bigger brains, lack tails

 

Ex humans and apes

Definition
Hominoids
Term
Based on DNA evidence what is the closest living relative of humans? 98.8% genetically identical to us
Definition
Chimpanzee
Term
What do we look at that tells us we 98.8% genetically similar to chimpanzee's?
Definition
Chromosome banding pattern
Term

Name the Ancient Hominid: 

 

4.4 million years ago 

 

Walked upright but not well

 

 

Definition
Ardi
Term

Name the Ancient Hominid: 

 
3.2 million years ago
 
True upright walking
Definition
Lucy
Term

Name the Ancient Hominid: 

 
2.3 million years ago
 
First known tool user
Definition
Homo habilis
Term

Name the Ancient Hominid: 

 
1.9 million years ago
 
Migrated out of Africa
Definition
Homo erectus
Term

Name the Ancient Hominid: 

 
0.25 million years ago
 
From Europe and Asia. 99.7% identical to us
Definition
Homo neanderthalensis
Term

Name the Pre-Embryonic structure:

 

fertilized egg

Definition
zygote
Term

Name the Pre-Embryonic structure:

 

Hollow ball with inner cell mass and trophoblast

Definition
blastocyst
Term

Name the Pre-Embryonic structure:

 

Inside a blastocyst - embryonic stem cells will develop into embryo

Definition
inner cell mass
Term

Name the Pre-Embryonic structure:

 

Inside a blastocyst - outer sphere. will form embryonic part of placenta

Definition
trophoblast
Term

Implantation: Blastocyst burrows into endometrium

 

Is this the 1st, 2nd, or 3rd step?

 

Trophoblasts secretes enzymes to create path

Definition
1st
Term

Implantation: Blastocyst burrows into endometrium

 

Is this the 1st, 2nd, or 3rd step?

 
Inner cell mass begins to develop into embryo
Definition
2nd
Term

Implantation: Blastocyst burrows into endometrium

 

Is this the 1st, 2nd, or 3rd step?

 
Trophoblast begins to develop into placenta
Definition
3rd
Term

Embryonic: Name the germ layer formed

 

Will form skin, nervous system

Definition
ectoderm
Term

Embryonic: Name the germ layer formed

 

will for connective tissue, bone, muscle

Definition
mesoderm
Term

Embryonic: Name the germ layer formed

 

will form lining of digestive tract, alveoli

Definition
endoderm
Term

Name the structure:

 

Interface between mother's and embryo's blood. Allow exchange of gases, nutrients, and waste

Definition
placenta
Term

Name the embryonic structure:

 

Ectodermal fold on back of embryo will eventually form CNS

Definition
neural groove
Term

Name the embryonic structure:

 

mesodermal will form muscle and bone

Definition
somites
Term

Name the embryonic structure:

 

all 3 germ layers will form several face and neck parts

Definition
pharyngeal arches
Term

Name the embryonic stage:

 

all vertebraes look similar

Definition
4 week embryo
Term

Name the embryonic stage:

 

looks more human

Definition
8 week
Term
Enzymes that cut DNA at specific sequences. Leaves overhangs of one strand. 2 different DNA molecules cut with the same enzyme can be combined
Definition
restriction enzyme
Term
DNA cloning is done through the use of what structure?
Definition
plasmid
Term

Name the structure:

 

circular DNA molecule that is copied when inside growing bacteria

Definition
plasmid
Term

Name the step of DNA cloning:

 

1st, 2nd, or 3rd?

 

Cut gene out of DNA

Definition
1st
Term

Name the step of DNA cloning:

 

1st, 2nd, or 3rd?

 

Insert gene into plasmid

Definition
2nd
Term

Name the step of DNA cloning:

 

1st, 2nd, or 3rd?

 

Put plasmid into bacteria and let bacteria make many copies

Definition
3rd
Term
This process makes many copies of DNA, use DNA polymerase enzyme to copy DNA of interest
Definition
PCR (Polymerase chain reaction)
Term

PCR:

 

Short pieces of DNA bind to ends of target sequence. Show polymerase where to start

Definition
primers
Term
How is PCR controlled?
Definition
Changing temperature several for 25-35 cycles
Term

Name the step of PCR:

 

1st, 2nd, or 3rd? 

 

high temp causes DNA to unwind

Definition
1st
Term

Name the step of PCR:

 

1st, 2nd, or 3rd? 

 

lower temp allows primers to bind to ends of target DNA sequence

Definition
2nd
Term

Name the step of PCR:

 

1st, 2nd, or 3rd? 

 

best temp for polymerase allows it to copy DNA

Definition
3rd
Term
Method to seperate piece of DNA and visualize
Definition
Electrophoresis
Term

Name the method of seperating DNA:

 

put DNA into gel and apply electric field

DNA moves towards + electrode

Smaller pieces move faster (seperate based on size)

Stain with dye that binds DNA and glows whne hit with UV light to see bands

Definition
electrophoresis
Term

The following are uses of what?

 

Make recombinant proteins - usually put gene into bacteria

Modify crops - agricultural uses

Modify animal - agricultural or research uses

Human gene therapy - correct a bad gene in pt.

Definition
cloned genes
Term
Different forms of the same gene
Definition
alleles
Term
Having 2 different alleles for a given gene, the gene is what?
Definition
heterozygous
Term
Having 2 of the same alleles for a given gene, the gene is what?
Definition
homozygous
Term

What alleles you actually have 

 

ex. Yy or yy

Definition
genotype
Term

Observable result of allele 

 

ex. yellow or green peas

Definition
phenotype
Term

Name the Mendel Law:

 

alleles for one gene seperate equally into gametes

Definition
Law of segregation
Term

Name the Mendel Law:

 

alleles for 2 different genes seperate independently (don't affect each other)

Definition
Law of independent assortment
Term
What is the exception to the law of independent assortment? (Mendel)
Definition
Genes that are close together on the SAME chromosome
Term
Failure of chromosomes to seperate correctly during meiosis
Definition
Non-disjunction
Term

Name the cause of nondisjunction:

 

3 copies of a chromosome

Definition
trisomy
Term

Name the cause of nondisjunction:

 

1 copy of a chromosome

Definition
monosomy
Term

Most cases of this cause the embryo to die?

 

(failure of chromosomes to seperate correctly during meiosis)

Definition
Non-disjuction
Term

The following are examples of what?

 

Down syndrome, monosomy X

Definition
Non-disjunction
Term
How does cancer relate to the cell cycle?
Definition
Proteins controlling cell cycle are mutated
Term

Name the gene:

 

mutation makes them constantly push cell through cycle

Definition
onocogene
Term

Name the gene:

 

mutation causes loss of normal function to stop cell cycle

Definition
tumor suppressor gene
Term
With the gradual accumulation of mutations, what happens?
Definition
cancer progression
Term

Name the term related to cancer progression:

 

increased cell division

Definition
hyperplasia
Term

Name the term related to cancer progression:

 

change of cell morphology (shape)

Definition
dysplasia
Term

Name the term related to cancer progression:

 

malignant, fast growing cells but staying in place

Definition
in situ cancer
Term

Name the term related to cancer progression:

 

cells spreading through tissue

Definition
invasive cancer
Term

Name the term related to cancer progression:

 

cells spreading to other organs

Definition
metastatic cancer
Term
These can be chemicals, radiation, microorganisms
Definition
carcinogens
Term

Name the term related to carcinogens:

 

cause the first mutation

Definition
initator
Term

Name the term related to carcinogens:

 

increases cell division and therefore, likelihood of further mutations

Definition
promoters
Term
Complete carcinogens do what?
Definition
Initiate and promote
Term
What are the defenses against cancer?
Definition
DNA repair, immune system, and cell death
Term

Name the defense against cancer:

 

needs to be done before the next round of DNA replication

 

Definition
DNA repair
Term

Name the defense against cancer:

 
cytotoxic T cells recognize different proteins and kill cancer cells
Definition
immune system
Term

Name the defense against cancer:

 
cells have a suicide program-kill themselves if DNA too badly damaged
Definition
cell death
Term

The following steps are involved with what?

 

Detach from tumor mass, move through tissue, cross capillary basement membrane, survive in blood, cross capillary basement membrane again, establish new tumor in different organ

Definition
metastasis - getting to another organ
Term
Cancer cells stimulate the growth of new blood vessels towards the tumor. Release chemical messengers that stimulate the vessels to grow
Definition
Angiogenesis
Term

Name the type of cancer treatment:

 

A: This removes the tumor

 

D: does not remove metastatic tumor cells and may miss invasive cells in same organ

Definition
surgery
Term

Name the type of cancer treatment:

 
A: drugs that target dividing cells; interfere with DNA synthesis
 
D: other dividing cells besides cancer - loss of hair, nausea/vomiting, anemia, infection
Definition
chemo
Term

Name the type of cancer treatment:

 
A: stronger effect on dividing cells than non-dividing cells
 
D: only targets one area - wont affect metastatic tumor in different oragn damages DNA of some normal cells - causes mutations
Definition
Radiation
Term

Name the new cancer treatment:

 

stimulate pt. immune system to attack tumor

 

Definition
immunotherapy
Term

Name the new cancer treatment:

 
drugs that block new blood vessel growth; starve tumor and decrease metastasis
Definition
anti-angiogenic therapy
Term

Name the new cancer treatment:

 
drug that blocks metastasis
Definition
anti-metastasis therapy
Term

Name the new cancer treatment:

 
drugs that block activity of oncogene
Definition
oncogene inhibitor
Term

Name the new cancer treatment:

 
give pt. an engineered virus that will infect and kill tumor cells only
Definition
viral therapy
Term

Name phase of the cell cycle:

 

mitosis (nuclear division) and cytokinesis (cell division) occur

Definition
M phase
Term

Name phase of the cell cycle:

 

cell growth, preparation of DNA synthesis

Definition
G1 phase
Term

Name phase of the cell cycle:

 

DNA synthesis

Definition
S phase
Term

Name phase of the cell cycle:

 

preparation for mitosis

Definition
G2 phase
Term

Name phase of the cell cycle:

 

exit from cell cycle

Definition
G0 phase
Term
What is the order of the cell cycle?
Definition
M, G1, S, G2, G0
Term
How is DNA copied?
Definition
Double helix unwinds, DNA polymerase adds new nulceotides one at a time. Nucleotides are complementary to parent strand
Term

DNA complementary nucleotides:

 

what pairs with A?

Definition
T pairs with A
Term

DNA complementary nucleotides:

 

What pairs with C?

Definition
C pairs with G
Term
Chromosomes are said to be _______ when cells have 2 copies of each chromosome (1 from mom and 1 from dad)
Definition
homogolous
Term
Both homologous chromosomes are copied in the S phase. These copies are called _____ ______
Definition
sister chromatids
Term

Name the phase of mitosis:

 

chromosomes condense, spindle forms

Definition
prophase
Term

Name the phase of mitosis:

 

chromosomes attach to spindle and line up at center of cell

Definition
metaphase
Term

Name the phase of mitosis:

 

sister chromatids seperate and move toward opposite sides of cell

Definition
anaphase
Term

Name the phase of mitosis:

 

chromosomes reach the end of spindle, chromosomes decondense, new nuclear envelopes form

Definition
teleophase
Term
Cleavage furrow forms and pinches off new daughter cells
Definition
cytokinesis
Term
Meiosis has how many divisions?
Definition
2
Term

Name the division of meiosis:

 

1 or 2?

 

Homologous chromosomes line up side by side at metaphase crossing over exchanges DNA (mix up mom and dad's genes0 entire chromosome (with both sister chromatids) goes to daughter cells

Definition
Meiosis 1
Term

Name the division of meiosis:

 

1 or 2?

 

works just like mitosis (sister chromatids seperate) result is 4 haploid cells (only one copy of each chromosome) each chromosome is mom's or dad's or a mixture

Definition
2nd division
Term
What is the result of meiosis?
Definition
4 haploid cells
Term

What is the following process?

 

DNA unwinds at the gene to be expressed. RNA polymerase copies by adding nucleotides (AU, GC), splicing (introns removed) mRNA moves out of nucleus to cytoplasm

Definition
transcription
Term

What is the following process?

 

ribosomes and tRNA read the genetic code. tRNA anticodon binds to mRNA codon. tRNA brings amino acid with it. ribosome holds everything in place and forms new peptide bond. starts at AUG codon and ends at stop codon

Definition
translation
Term

Name the type of mutation:

 

mutation that is passed to offspring

Definition
germ-line
Term

Name the type of mutation:

 

mutation not passed to offspring but can affect individual

Definition
somatic
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