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Final Bio 1305
Baylor University Nemec Final Exam
46
Biology
Undergraduate 1
12/08/2010

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Term
Steps to transcription
Definition
Initiation, Elongation, and termination
Term
Initiation requires a
Definition
promoter
Term
Promoters tell RNA polymerase
Definition
Where to start and which strand of DNA to use
Term
RNA polymerase moves
Definition
3' to 5'
Term
Initiation site
Definition
part of the promoter where transcription begins
Term
The genetic code relates
Definition
DNA to RNA and RNA to amino acids used to build the protein
Term
How many different Codons are there
Definition
64 or 4^3
Term
How many amino acids are there
Definition
20
Term
What is the start Codon
Definition
AUG Methionine
Term
Non coding base sequences
Definition
Intron
Term
What is left after splicing
Definition
Exons
Term
Single stranded nucleic acid from another source
Definition
probe
Term
Two things that happen after splicing
Definition
G cap and Poly A tail
Term
the three sites for tRNA bonding
Definition
EPA
Term
Stop Codons
Definition
UAA, UAG, or UGA
Term
Proteolysis
Definition
cutting of a polypeptide chain
Term
Glycosylation
Definition
addition of sugars to proteins to form glycoproteins
Term
Phosphorylation
Definition
adding phosphate groups to proteins and is catalyzed by protein kinases.
Term
Somatic mutations
Definition
ones that occur in body cells
Term
germ line mutations
Definition
occur in the cells of the germ line or the specialized cells that give rise to gametes
Term
Silent mutations
Definition
do not affect protein function
Term
gain of function mutation
Definition
gives the protein another function in addition to its previous function
Term
Conditional mutations
Definition
cause their phenotypes only under certain restrictive conditions but not under permissive conditions
Term
point mutation
Definition
gain loss or substitution of a single nucleotide
Term
chromosomal mutations
Definition
more extensive than point, change position or orientation of the DNA segment without removing any information
Term
Missense
Definition
base substitution accident
Term
Nonsense
Definition
a missense that reads a stop codon
Term
Frame shift
Definition
addition or subtraction that moves the entire genetic sequence
Term
Deletions
Definition
removal of part of the genetic material on the chromosome
Term
Inversion
Definition
two sections switched (on the chromosome)
Term
Section of the chromosome breaks off and attaches to another
Definition
Translocation
Term
restriction enzymes
Definition
monitor what comes in the cell, cuts down bacteria into noninfectious fragments, the cutting is restriction digestion
Term
SNP
Definition
single nucleotide polymorphisms are inherited variations involving a single nucleotide base
Term
STR
Definition
short tandem repeats are short repetitive DNA sequences that occur side by side on the chromosomes usually in the noncoding regions
Term
prion
Definition
proteinaceous infective particle
Term
multifactorial
Definition
caused by the interactions of many genes and proteins with one or more factors in the environment
Term
Genetic markers
Definition
reference points for gene isolation
Term
Genetic linkage
Definition
co inheritance of the marker and the disease causing allele
Term
Gene material is composed of
Definition
amino acids
Term
RNA differs from DNA
Definition
U instead of T, single stranded instead of double stranded,
Term
Central Dogma
Definition
irreversible, DNA to RNA to protein
Term
What does not follow the central dogma
Definition
retroviruses
Term
transcription
Definition
is the process of synthesizing an RNA molecule from a DNA template
Term
A codon that does not call for an amino acid sequence
Definition
stop codon
Term
People with PKU have
Definition
abnormal enzyme phenylalaine hydroxylase
Term
Prions Disease
Definition
An abnormal protein can infect and cause disease by altering the normal structure of a protein, causing the normal protein to assume an abnormal 3-dimensional structure
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