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Details Title: FHB section 1 Description: nerve, cardiac, vascular Total Flash Cards: 161 Created: 01/25/2005 10:49:45	To study from this set of flash cards, or to create your own your own study flash cards, register HERE. If you are already a registered user, CLICK HERE.
Cards Term CSF vs. Blood, higher Na? Definition CSF Term CSF vs. Blood, higher K? Definition Blood Term CSF vs. Blood, higher Cl? Definition CSF Term CSF vs. Blood, higher glucose? Definition Blood Term CSF vs. Blood, higher protein? Definition Blood Term alpha receptor antagonist Definition phenoxybenzamine Term beta receptor antagonist Definition propranolol Term musc receptor antagonist Definition atropine Term nico receptor antagonist Definition curare Term opiod peptide NTs and fxn Definition enkephalins, endorphins, inhibit pain Term embryonic derivation of nerual system Definition ectoderm Term embryonic derivation of microglia Definition mesoderm Term polyribosomes in nerve cells and their location Definition Nissl bodies, some, dendrite Term transport away from the soma (2 names) Definition anterograde, orthograde Term transport towards the soma Definition retrograde Term inner leaflets of Schwann cell membrane fuse to form the... Definition major dense line/inner mesoaxon Term outer leaflets of Schwann cell membrane fuse to form the... Definition intraperiod lines of myelin/outer mesoaxon Term large diameter nerve fibers Definition A alpha Term med diameter nerve fibers Definition A beta/delta Term small diameter nerve fibers Definition C Term an unencapsulated nerve ending responsive to light touch Definition Merkel's disc Term an unencapsulated nerve ending in a hair cell responsive to light touch Definition peritrichial ending Term an encapsulated nerve ending sensitive to fine touch Definition Meissner's corpuscle Term an encapsulated nerve ending sensitive to pressure and vibration Definition Paccianian corpuscle Term an encapsulated nerve ending sensitive to muscle stretch Definition NM spindle Term an encapsulated nerve ending sensitive to tendon stretch Definition Neurotendon spindle Term skeletal muscle TT V sensor Definition DHPR dihydropyridine receptor Term skeletal muscle SR Ca release channel Definition RyR ryanodine receptor Term 3 Subunits of troponin Definition CTI Term fast fibers rely on ___ for energy Definition glycolysis Term fast fibers are light/dark fibers Definition light Term TT found in what two types of muscle? Definition sk, car Term Z lines not found in what type of muscle? Definition sm Term 3 mechs of Ca entry into smooth muscle Definition IP3 induced SP release, ligand gates, Vm gates Term most Ca of sm muscles is extruded into the... Definition ex-cell space Term troponin found in... Definition sk, car Term regen of sk muscle Definition very limited Term regen of sm muscle Definition yep Term regen of car muscle Definition nope Term a myofiber is a... Definition myocyte Term a myofibril is a... Definition sarcomeric structure inside a myocyte Term sk type I is A/An? Definition A Term sk type II is A/An? Definition An Term vent/atr muscle more highly differentiated? Definition ventricle Term coronary vessles located in the... Definition epimysium Term perimysium more defined in sk/car? Definition sk Term location of TT in sk? Definition AI band Term location of TT in car? Definition Z band Term TT more developed in... Definition car Term SR more developed in... Definition sk Term 3 jxns at intercalated disc... Definition fasciae adherens, desmosome, GJ Term TT analogue in sm? Definition calveolae Term cells responsible for sk muscle regen? Definition satellite cells, residual myoblasts Term Ca control in sk? Definition calsequestrin in terminal cisternae Term Ca control in sm? Definition calveolae Term Ca control in car? Definition ex-cell sources Term direction of transmural conduction of cardiac AP? Definition endo --> epi Term causes of healing over of GJ? Definition inc Ca, dec pH Term effect of TTX? Definition block fast Na channels Term phases in slow cardiac APs? Definition 0, 3, 4 Term duration of slow cardiac AP? Definition 100-200 msec Term duration of fast cardiac AP? Definition 200-400 msec Term does NE affect K conductance? Definition no Term which type of cardiac AP demonstrates post-repol refractoriness? Definition Slow Term why do slow APs demonstrate post-repol refractoriness? Definition time dependance of slow Ca channels Term what on the EKG represents the AP duration in the ventricle? Definition QT Term is slow Ca current more important in the SA node or the Purkinje system? Definition SA node Term 3 requirements for re-entry loop Definition geometry, slow conduction, unidirectional block Term possible causes of DAD Definition digitalis toxicity, rapid HR, elevated catecholamines Term possible causes of EAD Definition acidosis, hypoK, slow HR Term why is an RonT PVC long? Definition it occurs during RRP of previous beat Term infarct does what to Nai? Definition inc Term infarct does what to Cai Definition inc Term infarct does what to RMP Definition inc Term infarct does what to Ko? Definition inc Term effect of hypokalemia on conduction velocity? Definition none Term effect of hyperkalemia on Rm? Definition decrease Term effect of hyperkalemia on Rm? Definition inc Term where do changes in pacemaker activity due to K conc primarily occur? Definition outside the SA node, Purkinje is sensitive Term annomalous rectifier channel... Definition IK1 Term delayed rectifier channel... Definition IK Term does atrial muscle have TT? Definition no Term how do catecholamines affect phospholambin? Definition phos it, inc. Ca-ATPase activity --> quicker pumping into SP -->quicker relaxation for quicker HR Term regulation of contraction amplitude in cardiac muscle? Definition Ca influx Term regulation of contraction amplitude in skeletal muslce? Definition AP freq, central recruitment Term in response to catecholamines, PKA phosphorylates... Definition Ca channels, phospholambin Term increasing preload during isotoinc contractions does what to amount of tension developed? Definition 0 Term increasing preload during isotoinc contractions does what to the amount of shortening? Definition inc Term increasing preload during isotoinc contractions does what to the max tension? Definition 0 Term increasing preload during isotoinc contractions does what to velocity of shortening? Definition inc Term increasing afterload during isotoinc contractions does what to the amount of shortening? Definition dec Term increasing afterload during isotoinc contractions does what to velocity of shortening? Definition dec Term increasing afterload during isotoinc contractions does what to total tension? Definition inc Term cause of the a wave on Wiggers? Definition atrial contraction Term cause of the c wave on Wiggers? Definition bulging of valves during ventricular systole Term contribution of the atrial kick at rest.. Definition 5% Term contribution of the atrial kick at exercise... Definition 15% Term cause of S3 Definition turbulent flow into ventricle - compliance, dilation Term avg cardiac index Definition 3.1 L/min/m sq Term venous P Definition 5 Term mean RAP Definition 2 Term systolic RVP Definition 25 Term systolic RVP is approx ___ LVP Definition 1/5 Term end-diastolic RVP Definition 2 Term systolic PAP Definition 25 Term diastolic PAP Definition 10 Term mean PAP Definition 15 Term mean LAP Definition 6 Term systolic LVP Definition 120 Term diastolic LVP Definition 6 Term mean Brachial artery P Definition 95 Term EF= Definition (EDV-ESV)/EDV x 100 Term what is meant by the diastolic reserve? Definition an inc in preload leads to a greater EDP leads to a greater SV Term what is meant by the systolic reserve? Definition an inc in contractility leads to a greater SV Term two consequences of CHF as depicted on the P/V curve? Definition dec contractility, dec compliance Term two ways to move venous return curve up and to the right Definition inc blood volume or inc venous tone Term inc in sympathetic activity does what to peripheral venous pressure? Definition inc Term percent of plasma that is protein Definition 7 Term nml albumin Definition 3.5-5 g/dL Term nml globulins Definition 2-4 g/dL Term percent of plasma that is organic molecules (not proteins)... Definition 2.1 Term percent of plasma that is salts... Definition .9 Term nml RBC number Definition 4-5x106/uL Term nml leukocyte number Definition 4-10x103/uL Term neutrophil diff Definition 60-70 Term eosinophil diff Definition 2-4 Term basophil diff Definition 0-1 Term lympo diff Definition 20-25 Term monocyte diff Definition 3-8 Term nml platelet number Definition 2-4x105/uL Term rxn catalyzed by Carbonic anhydrase Definition CO2 + H20 --> H2CO3 --> H+ + HCO3- Term Hgb content of an RBC Definition 33% Term composition of HbA1 Definition a2b2 Term composition of HbA2 Definition a2d2 Term HbS mutation Definition Glu-Val Term RBC size Definition 7-8nm Term contents of neutrophil spec gran Definition alkaline phosphatase, collagenase IV, lysozyme, lactoferrin Term contents of neutrophil azur gran Definition myeloperoxidase, defensins, collagenase, elastase, acid phosphatase Term 02- formed by Definition NAHPH oxidase Term contents of eo spec ex gran Definition histaminase, arylsulphatase, acid phosphatase, cathepsin, ribonuclease, eosinophillic peroxidase Term contents of eo epec in gran Definition major basic protein, eo cationic protein Term contents of baso spec gran Definition histamine, heparin, SRS, ECF, NCF (chemotactics) Term % of lymphocytes that are T Definition 85-90 Term % of lymphocytes that are B Definition 4-10 Term % of lymphocytes that are NK Definition 5 Term % of lymphocytes that are stem cells Definition .01 Term leukocytes of innate immunity Definition N, E, B, LNK Term leukocytes of adaptive immunity Definition LT, LB, LNK, M Term contents of delta granules of platelets Definition calcium, ADP, ATP, serotonin, histamine Term contents of alpha granules of platelets Definition fibrinogen, PDGF Term contents of lamda granules of platelets Definition lysosomes Term Virchow triad Definition 1. stasis, turbulence 2. endothelial injury 3. hypercoagulability Term Factor I Definition fibrinogen Term Factor II Definition prothrombin Term Factor III Definition tissue thromboplastin Term Factor VIII Definition antihemophilic globulin Term Factor IX Definition Xmas, plasma thromboplastin component Term Factor XII Definition Hageman factor Term Factor XIII Definition Fibrin stab factor Term Hemophilia A is a defect in Definition VIII Term Hemophilia B is a defect in Definition IX