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female repro
patho test 5
40
Medical
Graduate
11/16/2010

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Cards

Term
Pt comes abd discomfort, weight loss, dysuria, urinary frequency, and constipation. She is 65yo. What is your dx? What are the chances if pt first-degree relative has this
Definition
ovarian cancer . 50%
Term
1. ____________: b/l filled with clear straw colored fluid associated with hydatidiform mole , choriocaercinoma or H. therapy
Definition
ovarian cyst-- theca lutein
Term
30 y/o went under C-sec who is now in critical condition. she has fever, adnexal tenderness, peritoneal irritation and uterine tenderness.
what is you Dx? lab study?
Definition
pelvic US/ CBC
--> Metritis
Term
black female comes in to you office complaining abd pain and pressure, backache, vaginal bleeding/discharge, and urinary frequency/urgency. what do you think she has?
what could stimulate susceptibility to this condition?
Definition
Leiomyoma
-- estrogen and GH may stimulate susceptible. fibromuscular elements in uterine wall.
Term
ovarian cancer what do you recommend to pt?
Definition
brca1 and 2 testing
TVUS (Ultra sound) annually
CA 125 II anuually
prophylactic oophorectomy or salpingo-ooph... at age 35 for women at high risk
Term
this pt had sex first time when she was 13y/o, and has multiple sex partners. she has 5 kids and + for venereal infec.
s/s : pain and bleeding after intercourse. vag discharge.

what do you think she has? what is the major risk factor for this pt?
Definition
Cervical cancer
HPV - risk factor
Term
what kind of cell cancer is most often in cervical cancer
Definition
Squamous cell
Term
ASCUS

LSIL

HSIL
Definition
Bethesda System Classification of Pap Tests

ASCUS (atypical squamous cells of undetermined significance)

LSIL low-grade squamous intraepithelial lesion
early changes in the size and shape of the cells
abnormal cells are present only in the surface layer.

HSIL high-grade squamous intraepithelial lesion
more marked changes in the size and shape of the abnormal (precancerous) cells
Term
pt has hx of gono, nongono infec, syphilis and other few stds. she could have inflammation of what in the female reproductive apparatus?
Definition
uterine cervix: Cervicitis
Term
this female pt is obese and works for moving company. she has multiple vag deliveries. she is in your office complaining of vaginal pressure and dysuria and fullness. what is it?
Definition
cystocele
Term
on PE you found bulging mass beneath the post vaginal wall which pushes downward into lower vaginal canal. what it could be ?
Definition
rectocele


Levator ani muscles may become stretched or torn
Rectum may be torn from its fascial and muscular attachments to the pelvic wall


S&S: depends on severity
chronic constipation
rectal pressure
dyspareunia
Term
you got pt who is on ABiotics.

S&S: thick, white discharge
red, edematous mucous membranes
intense pruritus
painful urination
painful intercourse (why would you have sex in this condition lol)

what do you thing
Definition
vulvovaginitis
Term
this is a 45 yo female complaining of vaginal spotting and discharge, pain and change in urinary pattern. her mother took DES during pregnancy. what could she has?
Definition
vaginal cancer. women in mid 50s.
Term
pt has abnormally heavy and long uterine bleeding other than her period how do you chart this .. the word
Definition
menometrorrhagia
Term
this pt has inperforate hymen and her FSH is normal. she has cyclic pain due to blood backing up. what condition
Definition
primary amenorrhea

just read for lab:
If FSH is ↑ - most likely primary ovarian failure. (hypothalamus and pituitary are functioning - FSH to the ovary, but the ovary is failing to respond to the hormones)
If FSH normal or ↓ - likely the hypothalamus or pituitary

Evaluation of the thyroid and adrenal function may determine if the patient has isolated gonadotropin deficiency or panhypopituitarism
Term
pt comes in C/O sharp cramps usually in suprapubic region. she started her period 1.5yrs ago and has Nausea and HA.
condition?
Definition
dysmenorrhea- primary
Term
dysmenorrhea cramping pain ...how ..what happens?
Definition
Progesterone→ secretion of prostaglandins from endometrium→ uterine contractions and ischemia of endometrial capillaries→ cramping pain
Term
she had period for last 6 months and now its absent. she is dx with secondary amenorrhea.. what should you rule out first?
Definition
Pregnancy
Term
Absolute Contraindications to estrogen replacement therapy (ERT):

5 reasons ?
Definition
HX of

estrogen dependent tumors of the breast, uterus or kidney

genital bleeding of unknown cause

DVT

cerebrovascular disease

liver disease
Term
deficiency of adrenal enzyme 21-hydroxylase involved in cortisol production-- what condition
Definition
CAH
Term
Mutation in AR gene→ ↓ androgen receptor protein→ ↓ androgen response by cells→ various
sexual characteristics
Definition
AIS
Term
breast tissue extends into axilla-- name this
Definition
Tail of Spence
Term
male comes in C/O erythema of the nipple and tingling. inc sensitivity and pain. you dx him with paget's of the nipple. what is the underlining condition that he could have?
Definition
breast cancer

patho:It is believed that cells from a tumor inside the breast travel through the milk ducts to the surface of the nipple
Term
female with unilateral breast tenderness erythema. hx of DM steroid therapy and has inverted nipple. what could she has on the breast?
Definition
Abscess
Term
this 28 y/o newly mother wears tight bra to hide her big breast. S/S Rht breast is tender warm with erythema. she ahs fever and chills. what is your dx? what causes it and how?
Definition
staph or strep. Mastitis
retrograde infeciton from disruption of the epithelium of the breast
Term
this pt drinks 4 cups of coffee daily and now she complains of bilateral breast tenderness. labs shows hormone imbalance. she is 40Y/O. what do you think she has? is she at risk of Breast cancer? what do you do to confirm your Dx?
Definition
fibrocystic breast disease.


No association exists between this and breast cancer
Only certain types of tissue changes in women with fibrocystic breasts may predispose them to the development of malignancy


--> needle aspiration of a cyst
Term
3 benign neoplasm for breast
Definition
Fibroadenoma, adenoma & papilloma may appear at any time in a woman’s life from
childhood to old age
Term
this pt started her MCycle at age of 14 and now at age of 65 she is suffering from menopause. she had kid at age of 40. what is she at risk of? why?
Definition
Breast cancer

Hormonal: a major player
Longer exposure to estrogen & progesterone
(early onset of menses, late menopause)
Post menopausal hormonal therapy (HRT)
Term
what is the skin on the breast might looks like in breast cancer ?
Definition
Peau D' Orange
Term
1/2 of the BC are found int what quadrant
Definition
upper outer
Term
brawny edema ?
Definition
lymphedema skin changes after tx of bc .


fibrosis→ thick, rough skin
(brawny edema)
Term
Chandelier sign is noticed in what disease
Definition
PID when doing bimanual exam due to tenderness
Term
hemaonc chap
Definition
Term
4 major types of Leukemia
Definition
acute lymphoblastic leukemia (ALL)
acute myelogenous leukemia (AML)
chronic lymphocytic leukemia (CLL)
chronic myelogenous leukemia (CML)
Term
what are the bac for prostatitis ? she wants you to know this
Definition
pseudomonas aeruginosa
serratia
klepsiella
proteus species
enterococci
Term
80y/o male with pelvic pain, similar UTI symptoms, and sexual dysfunction (give me a break he is old )..what type of prostatitis?
Definition
type II
Term
male with pelvic pain and pain during or after EJACULATION...DRE findings also vary
what type of prostatitis?
Definition
Type III
Term
25% of postpubertal male with dx of orchitis will have H/O __________
Definition
mumps
Term
hallmark for nephrolithaisis
Definition
ureteral colic
Term
hallmark for pyelonephritis (all this F**king hallmarks ..man)
Definition
costoverterbral tenderness
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