Term
|
Definition
|
|
Term
|
Definition
- Gram <+> & <->
- Hydrophylic
|
|
|
Term
| Which enzyme do β lactams inhibit? |
|
Definition
D-Alanine Transpeptidase
(AKA: PBP)
- By transfering an Acyl group Acylation
|
|
|
Term
|
Definition
|
|
Term
| What are the 3 AAs that combine to make β-lactams? |
|
Definition
- L-α-Adipic acid
- L-Cysteine
- L-Valine
"an Adipose Cyst is the Valence electron" |
|
|
Term
| How much Penicillin-G = 1 USP unit? |
|
Definition
|
|
Term
| Primary mechanism of macrolide metabolism |
|
Definition
D-Alkylation
III amine --> I Amine |
|
|
Term
|
Definition
- 15 member ring
- OH --> Ether
|
|
|
Term
| preventing N-Dealkylation? |
|
Definition
|
|
Term
Macrolides Drug resistnce:
Binding site modification |
|
Definition
erm Gene
Methylase Modifies Adenosine
I Amine -> III Amine.
|
|
|
Term
| Which Macrolide is used exclusively in vets |
|
Definition
Chloramphenicol
- Bone Marrow toxicity
- Grey baby syndrome
|
|
|
