Term
| a 30 year old patient presenting with a history of spondylitis and degererative joint disease, slight blackish color to his ears. Lab findings are significant for urine that turns black upon standing. Enzyme deficiency |
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Definition
| Homogentisic acid oxidase |
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Term
| The cause of Homogentisic acid oxidase |
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Definition
| autosomal recessive trait inherited from both parents |
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Term
| Child comes into the office with his parents because his teacher suspect mental retardation. Physical exam reveals enamel hypoplasia, growth retardation, microcephaly, there is an unpleasant odor that remains. Diagnosis? |
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Definition
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Term
| Is caused by a gene defect causing the inability to not break down BCAA's |
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Definition
| Maple Syrup Urine Disease |
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Term
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Definition
| leucine, isoleucine, and valine |
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Term
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Definition
| phenylalanine hydroxylase |
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Term
| Simvastatin lowers serum cholesterol by inhibition of what enzyme? |
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Definition
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Term
| how man kilocals are in 1 g of carbohydrate |
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Definition
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Term
| Lead poisoning what enzyme is getting blocked |
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Definition
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Term
| Someone with bilateral cataracts. Which of the following enzymes catalyzes the production of sorbitol from blood glucose? |
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Definition
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Term
| 6 month old has hypotonia, hyperacusis, and no organomegaly. Bright red coloration of the central macula with surrounding retinal pallor. Accumulation of GM2 ganglioside. Diagnosis? |
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Definition
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Term
| Boy is brought to the clinic with hepatomegaly, severe hypoglycemia, hyperlipidemia, and hyperuricemia. He is diagnosed having a glycogen storage disease type 1a (von Gierke). What enzyme deficiency |
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Definition
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Term
| Elder patient showing, global demineralization on radiograph and is diagnosed with osteoporosis. Which of the following supplements has been shown to help maintain bone density with aging? |
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Definition
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Term
| ATP binds to what in muscle |
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Definition
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Term
| ATP binding to myosin does? |
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Definition
| causes the dissociation of myosin from actin and low energy conformation |
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Term
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Definition
| strengthens clotting by cross linking newly formed fibrin threads |
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Term
| What factors are part of the extrinsic pathway? |
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Definition
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Term
| Vitamin K dependent coagulants? |
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Definition
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Definition
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Definition
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Term
| When tissue factor is exposed what factor is activated? |
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Definition
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Definition
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Definition
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Term
| When both valves are closed, no blood is going anywhere? what is this called |
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Definition
| Isovolumic can be during early systole (isovolumic contraction) or diastole (isovolumic relaxation) |
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Term
| What does depleted 2,3 DPG do to the hemoglobin oxygen dissociation curve |
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Definition
| Shifts to the left, increasing the affinity |
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Term
| What causes shifts to the right on the hemolglobin ozygen dissociation curve |
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Definition
C02
altitude/acid
DPG
Exercise
Temperature |
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Term
| Carbon monoxide poisoning will cause oxygen dissociation curve to move to the..... |
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Definition
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Term
| Loading of O2 is facilitated when dissociation curve shifts... |
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Definition
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Term
| unloading of O2 is facilitated when dissociation curve shifts... |
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Definition
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Term
| Hemoglobin has 240x more affinity to........than oxygen |
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Definition
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Term
| For someone experiencing a heart attack. A 50% occlusion of the left main coronary atery will do what to the blood flow in that artery? |
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Definition
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Term
| Poiseuille's Law equation |
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Definition
8nl/pie (r^4) = resistance
n=viscosity |
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Term
| Laplaces law of alveoli states that what sized alveoli will have larger collapsing pressures |
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Definition
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Term
| Laplaces law in alveoli equation |
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Definition
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Term
| Why do smaller alveoli not collapse into bigger ones? |
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Definition
| Surfactant decreases surface tension and works better with smaller alveoli |
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Term
| What is surfactant produced by |
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Definition
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Term
| An infant has difficulty swallowing while breastfeeding. The cranial somatic dysfunction is at what? |
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Definition
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Definition
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Definition
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Definition
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Definition
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Definition
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Definition
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Term
| Following a bar fight, a patient suffers fracture of the occipital bone extending superiorly from the foramen magnum compromising what nerve |
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Definition
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Term
| Sensation of the tongue is what nerves |
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Definition
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Term
| Taste of the tongue is from: |
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Definition
| chorda tympani nerve from CN 7 |
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Term
| severe nausea and vomiting following 4 contrast medium probably stimulated a chemoreceptive trigger zone located in |
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Definition
| area postrema of floor of 4th ventricle |
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Term
| What causes weakness of the serratus anterior muscle causing winged scapula. |
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Definition
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Term
| Lat dorsi muscle problems following surgery to remove lymph nodes. Compromised what nerve |
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Definition
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Term
| Poorly fit crutches affect what nerve causing wrist drop |
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Definition
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Term
| During delivery, a baby's neck suffers a violent stretching of the brachial plexus during shoulder dystocia. What part of the Brachial plexus is injured? |
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Definition
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Term
| What nerve can be damaged during thyroid surgery, lung cancers (pancoast), aortic arch aneurysms, enlarged lymph nodes |
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Definition
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Term
| Falling on oustretched hand can produce what fracture of the wrist? |
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Definition
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Term
| A fracture found in a child only on one side of the cortex |
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Definition
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Term
| enzyme deficiency in MSUD |
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Definition
| a - ketoacid dehydrogenase |
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