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eyes
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203
Medical
Undergraduate 4
04/30/2017

Additional Medical Flashcards

 


 

Cards

Term
common causes of red eye?
Definition
conjunctivitis
blepharitis
corneal abrasion
foreign body
subconjunctival haemorrhage
keratitis, iritis, uveitis
glaucoma
chemical/radiation burn
episcleritis
scleritis
Term
features of acute angle closure glaucoma
Definition
severely painful
nausea, vomiting, headache
haloes and photophobia
pt usually 50 or >

hazy cornea
decreased VA
fixed, semi-dilated or oval pupil

mx: refer immediately
Term
normal range of IOP?
Definition
10-21mmHg
Term
diagnosis of acute angle closure glaucoma?
Definition
you need 2 of the following
occular pain
nausea and vomiting
hx of intermittent blurring of vision with haloes and at least 3 of the following

IOP >21mmHg
conjunctival injection
corneal epithelial oedema
mid-dilated non reactive pupil
shallow chamber in the presence of occlusion
Term
mx of acute angle closure glaucoma
Definition
lay pt supine
IV acetazolamide
topical agents used include:
beta blockers e.g. timolol, caution in asthma
prednisolone: 15mg every 15mins for 1 hour then hourly
pilocarpine: in pts with their real lens
phenylephrine: in pts who do not have their real lens.
Term
surgical mx of acute angle closure glaucoma
Definition
peripheral iridotomy (PI)
surgical iridectomy when PI not available. This option is more invasive.
lensectomy: when a cataracts lens has swollen and caused the acute angle closure
Term
how is peripheral iridotomy performed?
Definition
2 holes are made in each iris with a laser usually at 11o clock and 2 o clock to provide a passive for aqueous flow. the other eye is prophylactically treated as it is at risk of getting affected later.
Term
which 3 structures form the uvea?
Definition
iris
ciliary body
choroid

superficial to the uvea is the sclera and beneath it is the retina
Term
what is inflamed in anterior uveitis?
Definition
the iris.

it is also called iritis
Term
in severe uveitis you might see white clumps on the corneal endothelial surface. what are these?
Definition
These are keratic precipitates.(KPs)

those which are larger and greasy looking are called mutton fat KPs
Term
which HLA is associated with uveitis?
Definition
HLA b27
Term
causes of uveitis?
Definition
inflammatory due to AI disease: HLA b27
infectious causes: lyme disease, syphylis
iatrogenic: surgery, trauma, medication e.g rifabutin (Abx)
ischemic causes due to poor circulation
trauma
neoplastic infiltration.
herpes infection.
HIV
Term
symptoms of anterior uveitis?
Definition
red painful eye
photophobia; direct and consensual
pain worse when trying to read
onset can be few hours/days
there can be xs tear production and associated headache
Term
keratic precipitates are characteristic of which condition?
Definition
uveitis
Term
iris atrophy is a diagnostic feature for uveitis due to?
Definition
herpes.
Term
how is the severity of uveitis graded?
Definition
by the number of cells seen in the aqueous humour. this is graded from 0-4
0 = no cells seen
4 = > 50 cells
Term
referral from primary care for a pt presenting with anterior uveitis?
Definition
refer to ophthalmologist within 24 hours
Term
mx of uveitis
Definition
cycloplegic drugs e.g. cyclopentolate 1% used to paralyse cillary body. this relieves pain and prevents adhesions between iris and lens
topical steroids
if macular oedema reoccurs then immunosuppressors e.g. ciclosporin
Term
which is the only pt group that is currently screened for uveitis?
Definition
children with juvenile idiopathic arthritis.
Term
complications of anterior uveitis
Definition
macular oedema
secondary cataract
posterior synechiae: can cause blockage of aqueous flow and lead to raised IOP
Term
symptoms of conjuctivitis
Definition
red eye
irritation, grittiness and discomfort are typical
discharge

photophobia is not typical and VA should remain unaltered.
Term
typical hx of pt with conjunctivitis?
Definition
close contact with another infected person
recent URTI
eyes glued together after sleep, mucopurulent discharge.
there may be pre auricular lymphadenopathy
Term
which virus causes most viral conjunctivitis?
Definition
adenovirus.
Term
in conjunctivitis how can you differentiate between allergic, viral and bacterial forms from the hx?
Definition
itching? allergic
reoccuring? viral
pre auricular lymph node? more likely viral or atypical bacteria: gonococcal/ chlamydia
absence of itching and absence of contact with infected person make bacterial more likely
purulent d/c: bacteria
watery d/c: viral
Term
conjunctival follicles are round collections of lymphocytes typically seen in what type of conjunctivitis?
Definition
viral mostly
Term
mx of simple bacterial conjunctivitis
Definition
reassurance that condition is self limiting and resolves in 1-2 weeks. come back if it is going on for > 2 weeks.

remove contact lens until 24 hours after cleared infection
wipe away secretions using damp cotton wool

pts often resist conservative rx so a pragmatic approach is taken to rx with ABx.. treat if causing distress, absence from school/work or if pt wears contact lens but advice them they should not wear lens until 24 hours after infection has been cleared.
Term
what Abx of choice is given in conjunctivitis?
Definition
chloramphenicol.
avoid in pregnancy, breast feeding, hx of myelosuppression or blood dyscrasias,

fusidic acid is an alternative for staph infections and in pregnancy.
Term
which group are at risk for eye infections by pseudomonas?
Definition
contact lens wearers.
Term
what ix should you do in someone who presents with a foreign body in their eye?
Definition
slit lamp examination
Term
what is the first priority in evaluating a corneal injury?
Definition
it is to include/exclude a full thickness injury therefore a ruptured globe.
Term
what test is used to see if an injury is penetrating?
Definition
Siedel's test

apply 10% fluorescing to the affected area and view using a Wood's light or cobalt blue light source. if aqueous fluid is leaking through this will be seen as a pale or clear liquid in a pool of dye. if this test is positive then rx for open globe injury
Term
what imaging modality is used for evaluating orbital fractures and intra orbital foreign bodies?
Definition
CT scan
Term
corneal abrasion: mx and features
Definition
analgesia with NSAIDs
patching is not recommended: may delay healing
topical Abx commonly prescribed to prevent bacterial superinfection
Term
chloramphenicol is an Abx used in eye infections. what type of people should not be given this Abx? What is the alternative
Definition
pregnant
breastfeeding
myelosupression
hx of blood dyscrasia
intolerent to cholamphenicol

alternative: fusidic acid
Term
contact lens abrasions should be treated with what type of Abx?
Definition
antipsuedomonal Abx
Term
causes of subconjunctival haemorrhage?

this is a benign self limiting condition when not associated with systemic illness
Definition
valsalva manœuvre: coughing, straining
trauma
HTN
bleeding disorder
warfarin therapy
coronary heart disease
Term
ix in subconjunctival haemorrhage?
Definition
check BP

discourage elective use of aspirin products or NSAIDs
Term
blepharitis - inflammation of the eyelid
what is the mx?
Definition
lid Hygiene
warm compress
lid massage
lid cleansing
Term
Ddx of non painful red eye acute?
Definition
subconjuctival haemorrhage
episcleritis
conjunctivitis
Term
which type of glaucoma is associated with hypermetropia and which angle is associated with myopia??
Definition
hypermetropia = acute angle closure glaucoma
myopia = primary open angle glaucoma
Term
risk factors for primary open angle glaucoma
Definition
advanced age
FHx
black ethnicity
myopia
HTN
diabetes melitus
Term
signs of Horner's syndrome on eye examination
Definition
miosis - (constricted pupil)
ptosis
endopthalmos
+/- anhidrosis on that side of face
Term
common causes of sudden painless loss of vision?
Definition
central retinal artery obstruction
central retinal vein obstruction
retinal detachment
vitreous haemorrhage
ischemic optic neuropathy (temporal arteritis or atherosclerosis)
Term
central retinal vein occlusion features
Definition
this is more common than artery occlusion
the incidence increases with age
causes: glaucoma, polycythaemia and HTN
several retinal haemorrhages usually seen on fundoscopy
Term
central refinery artery occlusion, features
Definition
due to thromboembolism or arteritis
cherry red spot
afferent pupillary defect
Term
how to differentiate between
posterior vitreous detachment
retinal detachment
vitreous haemorrhage
Definition
posterior vitreous detachment: flashes of light (photopsia) in peripheral vision. floaters often on temporal side of central vision

retinal detachment: dense shadow starting at periphery and proceeding to central vision. a veil/curtain over the field of vision. straight lines appear curved. central visual loss.

vitreous haemorrhage: large bleeds cause sudden visual loss, moderate bleeds may be described as numberous dark spots and small bleeds may be described as floaters.
Term
what is the common cause of blindness in the UK?
Definition
age related macular degeneration.

there is degeneration of the central retina, this is called the macula
Term
what is dry macular degeneration characterised by?
Definition
drusen. these are yellow round spots in Bruch's membrane
Term
which type of macular degeneration is characterised by choroidal neovascularisation and leaking of serous fluid?
Definition
wet macular degeneration
Term
risk factors for macular degeneration
Definition
age > 60
FHx
smoking
more common in caucasians
high cumulative sun exposure
female sex
Term
features of macular degeneration
Definition
central vision affected first
straight line appear wavy or crooked
there may be central scotomas
Term
ix and dx of macular degeneration
Definition
OCT provides cross sectional view of macula
if neovascularisation is present then fluorescing angiography is performed
Term
NICE general mx for macular degenration
Definition
refer to opthalmology within 1 week
encourage them to stop smoking
high dose beta carotene, zinc, vit C and E may help slow down visual loss for pts with established degeneration but avoid in current smokers as it may increase risk of lung cancer
Term
rx for dry and wet mac degeneration
Definition
dry MD: currently no rx
wet MD: anti VEGF: intravitreal injections of ranizimubab or afibercept.
photocoagulation
photodynamic therapy
Term
what is the brand name for afibercept?
Definition
eyelea
Term
what is the brand name for ranizimubab
Definition
lucentis
Term
for pts with a history of asthma and glaucoma they cannot use beta blockers, what becomes first line in these situations?
Definition
prostaglandin analogue e.g. lantaprost
Term
beta blockers e.g timolol

MOA
SE
Definition
reduces aqueous production
avoid in asthmatics and pts with heart block
Term
prostaglandin analogues e.g lantaprost

MOA
SE
Definition
increases uveosceral outflow
SE: brown pigmentation of the iris
administered once daily
Term
pilocarpine

what type of drug is it?
MOA
SE
Definition
muscarinic receptor agonist
MOA: increases uveoscleral outflow
SE: constricted pupil, headache and blurred vision
Term
what is dorzolamide?
MOA
SE
Definition
its a carbonic anhydrase inhibitor
it reduces aqueous production
SE: systemic absorption may cause sulphonamide type reactions
Term
give an example of an alpha 2 receptor agonist used in primary open angle glaucoma
MOA
SE
Definition
reduces aqueous production AND increases outflow
SE: hyperaemia (xs of blood in vessels supplying organ or body)
avoid if taking MAOI or TCA antidepressants
Term
what surgery might be considered in glaucoma if drops are working?
Definition
trabeculectomy
Term
causes of papiloedema
Definition
raised ICP
space occupying lesions, neoplastic and vascular
malignant HTN
idiopathic intracranial HTN
hydrocephalus
hypercapnia

rare causes include: hypOparathyroid, hypOcalcemia and vit A toxicity
Term
classical symptoms of optic neuritis?
Definition
visual loss; blind spot; central scotoma
eye pain: worse on eye movement
red desaturation
lethargy is a common non specific symptom
Term
left homonymous hemianopia.

where is the lesion?
Definition
right optic tract
Term
PITS
Definition
parietal -inferior
temporal- superior
Term
is there is macula sparing where is the lesion?
Definition
occipital cortex
Term
tunnel vision AKA bitemporal hemianopia,
where is the lesion?
Definition
optic chiasm
Term
in bitemporal hemianopia you can have an upper quadrant defect or a lower quadrant defect. where are relative lesions for each?
Definition
if upper quadrant defect is > lower quadrant defect this mean there is inferior chasmal compression most likely to be the pituitary

if the lower quadrant defect is more than the upper quadrant defect then this means there is superior chasmal compression commonly a craniopharyngioma,
Term
common eye lid problems?
Definition
blepharitis: inflammation of eyelid margins typically leading to red eye
stye: infection of glands of the eyelids
chalazion: meibomian cyst (rounded appearance and no yellow head)
entropion
ectropion
Term
what is a stye?
Definition
infection of glands of the eyelids
there are internal and external stye
Term
what is the latin name for external stye?
Definition
hordeolum externum

this is usually a staphylococcal infection of the
glands of Zeis (sebum making)
OR
glands of Moll (sweat making)
Term
what is the Latin name for an internal stye?
Definition
hordeolum internum: this is an infection of the meibomian glands and it may leave a residual chalazion (Meibomian cyst)
Term
mx of stye?
Definition
hot compress and analgesia

Abx are only recommended if there is associated conjunctivitis.
Term
a chalazion is AKA meibomian cysts
features of it?
Definition
presents as firm painless lump in eyelid
majority of cases resolve spontaneously but some require surgical drainage
Term
ischemic optic neuropathy is one cause of painless loss of vision. which arteries are obstructed?
Definition
short posterior ciliary arteries. this causes damage to the optic nerve
Term
night blindness and tunnel vision what are you thinking?
Definition
Retinitis pigmentosa
Term
which part of the retina does retinitis pigmentosa affect?
Definition
the peripheral retina.
this results in tunnel vision.

on fundoscopy there is black bone spicule shaped pigmentation in peripheral retina.
Term
34 year old man with ankylosing spondylitis presents with painful red eye and mild photphobia. what are you thinking he has that is associated with ankylosing spondylitis?
Definition
anterior uveitis.
Term
conditions associated with anterior uveitis?
Definition
ankylosing spondilytis
reactive arthritis
ulcerative colitis, crohns disease
Behcets disease
Term
mx of anterior uveitis?
Definition
urgent review by ophthalmologists
cycloplegics (dilate the pupil and this helps relieve pain and photophobia) e.g. atropine and cyclopentolate
steroid eye drops
Term
Horner's syndrome can be due to central, pre and post ganglionic lesions. in which one of these categories is anhidrosis of the face absent?
Definition
in post ganglionic lesions.

these are remembered by all the Cs
carotid artery dissection
carotid aneurysm
cluster headache
cavernous sinus thrombosis
Term
mx of acute angle closure glaucoma?
Definition
urgent referral
reduce aqueous secretions with acetazolamide
induce pupilary constriction with topical pilocarpine
Term
ptosis and constricted pupil = Horner's syndrome

what about Ptosis and dilated pupil?
Definition
third nerve palsy
Term
what is dacryocystitis?
features of it?
mx?
Definition
inflammation of the lacrimal sac
features: watery eye (epiphora)
swelling and erythema at inner canthus of eye
mx: systemic Abx
IV Abx if there is periorbital cellulitis
Term
watery eye and swelling and erythema of the inner canthus of the eye?
Definition
dacryocystitis

mx: systemic Abx
Term
Management of infective conjunctivitis
Definition
it is normally self limiting that settles w/o rx within 1-2 weeks
when Abx are offered these are the common ones:-
Chloramphenicol: drops are given 2-3 hourly initially
Chloramphenicol ointment is given ads initially

Topical fusidic acid is an alternative and should be used for pregnant women. Treatment is twice daily

Contact lens should not be worn during an episode of conjunctivitis
Advice should be given not to share towels
School exclusion is not necessary
Term
in which 2 conditions might a hypopyon be seen?
Definition
anteriour uveitis
keratitis

in keratitis the pupillary reaction is normal
where as in anterior uveitis it isn't.
Term
A 23-year-old female presents with recurrent headaches. Examination of her cranial nerves reveals the right pupil is 3 mm whilst the left pupil is 5 mm. The right pupil constricts to light but the left pupil is sluggish. Peripheral neurological examination is unremarkable apart from difficult to elicit knee and ankle reflexes. What is the most likely diagnosis?
Definition
Holmes-Adie pupil

a benign condition most commonly seen in women. It is one of the differentials of a dilated pupil.
unilateral in 80% of cases
dilated pupil
once the pupil has constricted it remains small for an abnormally long time
slowly reactive to accommodation but very poorly (if at all) to light

Holmes-Adie syndrome:
association of Holmes-Adie pupil with absent ankle/knee reflexes
Term
features of central retinal vein occlusion
Definition
sudden painless loss of vision, severe retinal haemorrhages on fundoscopy
Term
Adverse effects include brown pigmentation of the iris
Definition
Lantaprost
Term
First-line treatment in a patient with a history of heart block
Definition
lantaprost
Term
Causes pupillary constriction, blurred vision and headaches
Definition
pilocarpine
Term
central field loss occurs from degeneration of the fovea. some examples?
Definition
ARMD
optic neuropathy
macular holes
retinal artery occlusion
Term
examples of conditions where there is peripheral field loss?
Definition
glaucoma
retinal detachment
retinitis pigmentosa
chorioretinitis
branch retinal artery occlusion
Term
where would the visual loss be if it was a central retinal artery occlusion?
where would visual loss be reported if it was a branch retinal artery occlusion
Definition
central retinal artery occlusion = central visual loss
branch retinal artery occlusion = peripheral visual loss.
Term
which test assesses the eyes greatest power of resolution?
Definition
visual acuity
Term
what does visual sensitivity measure?
Definition
peripheral visual field
Term
which grid testing assesses the central 10 degrees of visual field?
Definition
amsler grid testing
Term
where is the fovea located?
Definition
within the macula.
together they are responsible for central vision
Term
what fundoscopy changes would you see in central retinal vein occlusion?
Definition
it will look hyperaemic compared to retinal artery occlusion that looks pale
there are many haemorrhages and cotton wool spots. it will look like a storm
Term
which drug can cause a classical 'bull's eye maculopathy' affecting the centre of the field
Definition
chloroquine

NB: vigabatrin causes field defects in 40% who take it
Term
what must a person do with regards to driving if they are diagnosed with a visual loss.
what is the name of the specific test used to assess their vision?
Definition
they should not drive until the visual defect has been formally assessed.
they should inform the DVLA.
the DVLA will organise a specific visual test called the ESTERMANN'S visual field test. this is carried out by one of their approved optometrists who will report back to them and tell them if you are ok to drive.
Term
features of absolute glaucoma: this is the end point of glaucoma
Definition
no functioning vision
stony appearance to eye
loss of pupillary reflex
very painful
Term
what is glaucoma?
Definition
disease of the optic nerve

there is progressive loss of retinal ganglion cells and their axons.
Term
whats the word for short sightedness?
Definition
myopia.

myopia is a risk factor for primary open angle glaucoma
Term
what is the normal cup:disc ratio ?
Definition
0.3
Term
grading of glaucoma
Definition
mild: early visual field defects
moderate: arcuate scotoma and thinning of neuroretinal rim (cupping)
severe: extensive visual field loss and marked thinning of the neuroretinal rim
end stage : only smaller residual visual field remains. cup:disc in the region of 0.9-1.0
Term
since 2000 what type of glaucoma med is 1st choice. clue: not beta blocker
Definition
prostaglandin analogue
Term
what is the action of prostaglandin analogues?
Definition
they increase aqueous outflow by uveoscleral route.

SE: browning of iris, lengthening of eyelashes
CI: active uveitis, pregnancy, breast feeding
Term
MOA of beta blockers in glaucoma
Definition
they reduce aqueous secretion by blocking beta receptors on the ciliary bodies.
CI: bradycardia, heart block, asthma, COPD
SE: nightmares, depression, bradycardia, irritation, erythema, dry eyes.
Term
MOA carbonic anhydrase inhibitors
Definition
they reduce aqueous secretion by ciliary body.
CI: breast feeding, renal/hepatic impairment, metabolic disturbance, sulfonamide sensitivity
SE: taste disturbance, dizziness, fatigue, sulphonamide related side effects.
Term
MOA of sympathomimetics in glaucoma
Definition
they reduce aqueous secretion and increase outflow through trabecular meshwork.
CI: MAOIs, angle closure glaucoma.
SE- ocular : mydriasis, dry eye, smarting/redness of eye.
systemic SE:lethargy, hypotension
Term
MOA of miotics

these can cause brown pain
systemic SE: sweating, GI disturbance and bradycardia
Definition
they cause cilliary muscle to contract and this opens up drainage channels in trabecular meshwork.
CI: retinal holes and in situations like uveitis where ciliary contract is undesirable
occular SE: miosis, can affect driving due to blurred vision
those with dark iris need more. caution in heart disease, HTN, parkinson's disease and UTract obstruction
Term
when should laser and surgery be considered in glaucoma?
Definition
after lack of success with 2 different drops
Term
name of trabeculoplasty surgery used in glaucoma?
Definition
argon laser trabeculopplasty (ALT)
selective laser trabeculoplasty (SLT)
Term
surgery used in angle CLOSURE glaucoma. what does it involve?
Definition
YAG laser iridotomy: a small hole is made in the iris to enhance flow
Term
what is a relevant disability as opposed to an absolute disability?
give examples
Definition
relevant disability: visual field DEFECT
absolute disability: reduced VISUAL ACUITY
Term
what is the most common cause of gradual visual loss in the developed world?

what is the worldwide cause?
Definition
macular degeneration
followed by diabetic retinopathy

worldwide it is chlamydial infection causing trachoma.
Term
causes of bilateral acute loss of vision?
Definition
bilateral occipital lobe ischemia or infarction
bilateral occipital trauma
severe bilateral papilloedema
rapidly progressing chiasmal compression
bilateral optic nerve damage e.g. methyl alcohol poisoning
Term
which form officially registers someone as sight impaired?
Definition
CVI certificate of vision impairment.

you need a consultants signature to be registered.
registration is voluntary but does entitle you to benefits and concessions.
Term
complications of those with visual problems
Definition
social isolation
falls and accidents
restriction of activities and the need for supervision
education difficulties
reduced employment perspectives,
Term
what does distortion of straight lines indicate on an ambler grid?
Definition
serious macular pathology and warrants an urgent referral
Term
if visual acuity is improved using a pinhole what does this indicate?
Definition
a refractive error
Term
painful loss of vision tend to have a more sinister pathology.
name some causes
Definition
progressive neoplastic (choroidal melanoma) or inflammatory process (chorioretinitis)
systemic problem: sarcoidosis
optic nerve lesions: optic neuritis or neuroma
intracranial masses, HTN or pathology
Term
what does a driver need to be able to do in order to keep their license?
Definition
read a number plate 20-20.5 metres
minimum VA 6/12

if they don't have this they should not drive and inform DVLA
Term
whats the procedure for cataracts and informing DVLA?
Definition
often safe to drive and don't need to tell them
Term
if you have a visual field defect do you have to notify the DVLA?
Definition
yes you do and then they will assess you
Term
if you have diplopia what do you need to do with regards to DVLA?
Definition
do not drive, let them know.
if you are group one driver and diplopia is controlled by glasses of by a patch then you may get your license back.
if you are a group 2 driver then patching is not acceptable to get your license back and you will not be permitted to drive.
Term
if you are colourblind do you need to let DVLA know?
Definition
no you don't and you can continue to drive but if you have night blindness you need to let DVLA know.
Term
you have blepharospasm and drive.. do you need to stop driving and tell DVLA?
what is blepahrospasm?
Definition
uncontrollable and sometimes painful movements around the eye.
you need to stop driving and tell DVLA
they will get a specialist opinion before giving your license back
Term
what diameter AAA disqualifies someone from driving?
Definition
> 6.5cm

you need to tell DVLA if your AAA is > 6cm
Term
what is the most common refractive error?
Definition
myopia
it means near sighted where light falls in front of rather than on the retina.
distant objects appear blurry but near objects are fine
it is corrected by giving CONCAVE lens with negative focusing power. this lengthens the rays and makes it hit the the retina
severe myopia increases risk to glaucoma, cataracts and retinal detachment
Term
hyperopia is called far sightedness. give features and management of this condition
Definition
when light falls behind the retina
close objects appear blurry but far objects are normal
managed by convex lens
Term
if you are short sighted where is the light falling in relation to the retina and how can you fix this?
Definition
light is falling in front of the retina rather than on it.
you fix it by giving a concave lens
Term
if you are far sighted where is the light falling in relation to the retina and how can you fix it?
Definition
light is falling behind the retina rather than on the retina
you fix it by giving convex lens
Term
presbyopia. problem focussing on close or far objects?
what is the pathophysiology?
Definition
there is progressing problem to focus on near objects.
the problem is due to hardening of the lens by decreased levels of alpha crystallin. this causes the eye to focus light behind rather than on the retina.
mx is with reading glasses that have a higher focusing power in the lower portion of the lens
Term
pathophysiology of binocular double vision
how can you get rid of binocular double vision
Definition
this occurs when the images produced by the 2 eyes do not absolutely match
if one eye is covered then the diplopia disappears
Term
what is the most common cause of binocular diplopia?
Definition
cranial nerve palsies e.g. abducent nerve palsy
Term
causes of monocular diplopia
Definition
cornea and lens problems including cataracts
eye muscle problems: graves disease, MG
nerve problems: CN III, IV, VI. MS, GBS, DM
Term
which muscle may be trapped in an inferior orbital fracture that can cause diplopia?
Definition
inferior rectus
Term
brain problems that can present with diplopia?
Definition
migraine
raised ICP
strokes
aneurysms
Term
oblique eye muscles move the eye OUTWARDS as well as up and down. because they are on a pulley they move the eye the opposite way to which the name suggests. knowing this information which way does the superior oblique move the eyeball and which way does the infer oblique move the eyeball?
Definition
superior oblique: Down and Out
inferior oblique: Up and Out

Superior oblique is AKA the Tramp's muscle
Term
eye movements of the following muscles
superior oblique
inferior oblique
superior rectus
inferior rectus
medial rectus
lateral rectus

include nerve supply.
Definition
superior rectus moves eye up.
in palsy the eyeball is looking down
CN: III

inferior rectus moves eye down
in a palsy the eye is looking up
CN: III

medial rectus moves eye medially
in palsy is it laterally resting
CN: III

lateral rectus moves eyeball laterally
in a palsy it is medially resting
CN: VI

Superior oblique moves eyeball down and out
in palsy it is resting up and in
CN: IV

inferior oblique moves eye up and out
in a palsy it is resting down and in
CN: III
Term
what are the 5 red flags in diplopia?
Definition
pupil involvement with 3rd nerve palsy suggests posterior communicating artery aneurysm. the pupil reacts poorly

diplopia affecting 2 or more of lip, pupil and eye movement, Horner's syndrome due to carotid dissection or inflammatory neuropathy (GBSyndrome)

multiple cranial nerve palsies suggest intracranial or meningeal tumour

diplopia with weakness and fatigue suggests MG

Diplopia with new onset headache and scalp tenderness suggests GCA
Term
low vision aids can be optical or non optical give an example of an optical visual aid
Definition
illuminated magnifiers
handheld magnifiers
flat magnifiers

for viewing faraway objects include binoculars
Term
low vision aids can be optical or non optical give an example of a NON optical visual aid
Definition
anglepoise lamp
bold print books
liquid level indicators which beep to stop you burning yourself when using hot water.
Term
which system is used to standardise eye trauma terminology
Definition
The Birmingham Eye Trauma Terminology System
Term
define
eye wall injury
open globe injury
closed globe injury
Definition
eye wall injury: confined to cornea and sclera
closed globe injury: eye wound is not full thickness
open globe injury: full thickness eye wound
Term
high velocity injury raises possibility of penetrating injury.
what do forceful injuries such as a punch cause?
Definition
blowout injury
Term
what should you not do in an OPEN globe (penetrating) injury?
Definition
do not manipulate the eye
do not apply any pressure e.g. do not measure IOP
do not patch the eye
Term
example of urgent eye injuries that may rapidly lead to blindness?
Definition
chemical burns
retrobulbar hemorrhage
open globe injuries
Term
serious/red flag symptoms in eye injuries
Definition
reduced and progressive VA
pain that is not relieved by local anaesthetics
diplopia
flashes and new floaters and that can indicate retinal injury
Term
what does a tear shaped pupil and a positive SIedel's test both indicate?
Definition
an open globe injury
Term
serious signs in eye injury
Definition
deep lid laceration
subconjunctival haemorrhage
pupil, iris or fundal abnormalities
abnormalities of eye movements
Term
scan of choice to detect orbital trauma, fracture and intra ocular foreign body (IOFB)
Definition
CT scan
Term
USS is good for evaluating the globe but when is it contra indicated?
Definition
in an open globe injury
Term
if a metallic foreign body was suspected which mode of investigation would be contra indicated?
Definition
MRI
Term
from acid and alkali injuries to the eyes, which one is better to have and what is the reason?
Definition
acid create a barrier to the tissue protein and this forms a barrier for further tissue penetration. this is the reason why it is better to have an acid rather than an alkali burn.

alkali burns produce penetrating eye injuries more quickly than acids.
Term
mx of a chemical burn
Definition
before anything do 3 I's

irrigate
irrigate
irrigate
Term
normal PH of the eye?
Definition
7.4
Term
mx of chemical burns to eyes
Definition
irrigate irrigate and irrigate until pH of eye is back to physiological pH this is 7.4 then examine
Term
how to irrigate following chemical eye injury?
Definition
saline bags, giving set, towel
sit pt by sink
give anaesthetic drops into their eyes
explain what you are doing, remove their contacts if they are wearing them
Term
what volume of fluid may be needed to neutralise the pH in a severe chemical eye injury?
Definition
up to 20 litres
Term
how long should you irrigate an eye in a chemical injury?
Definition
15-30 mins irrigate whilst you refer and take a history
check pH every 5 mins
if you need to install drops then install them every 5 mins as they will wash away too with irrigation
after irrigation check VA in both eyes.
Term
how are CS (tear) gas injuries treated?
Definition
by blowing cool air into the eyes
Term
summary mx of chemical eye injury
Definition
irrigation using saline. you will need a lot of bags
you want to get the pH to normal. This is 7.4
in severe injuries especially with alkalis you may need up to 20l of fluid to get the pH back
You may have to give anaesthetic drops if the pt is in pain whilst you irrigate
you should give the drops and check pH every 5 mins.
explain what you are doing to the patient as this can be a distressing time.
whilst you are irrigating make a referal and take a history.
irrigate for 15-30 minutes, once finished check VA in both eyes and record.
also give broad spec Abx
Term
features of retrobulbar haemorrhage
Definition
severe eye pain
progressive visual loss
progressive opthalmoplegia
proptosis

bleeding in orbital cavity compresses orbital structures. this causes ischema of the eye and optic nerve.

this is an eye emergency and surgery is needed to prevent visual loss.
Term
what is the mx of retrobulbar haemorrhage?

what is the role of medical mx?
Definition
surgical rx definitive: incision at LATERAL CANTHUS to relive high IOP

medical mx can buy time: IV mannitol, dexamethasone and acetazolamide.
Term
mx of open globe injury
Definition
do NOT touch, manipulate or prod eye
use a raised eye shield, if not available then make one from the bottom of a polystyrene cup
refer immediate and give Abx cover
make pt NBM
avoid any increase pressure to the eye: tell pt not to blow nose, cough, strain or bend over.
provide analgesia and anti emetics
rx as high tetanus risk wound
Term
why should you not attempt to remove a penetrating FB lodged in the eye yourself?
Definition
it may cause prolapse of the eye contents
refer immediately
treat as open globe injury
Term
miosis = small pupil
what is the word for a large pupil?
Definition
mydriasis
Term
what does a D shaped pupil indicate?
Definition
detachment of the iris from its root base.
Term
signs of non accidental eye injuries in children

referal of these injuries is mandatory
Definition
retinal haemorrhages
peri occular bruising or lid laceration
subconjunctival haemorrhage
unexplained lens dislocation or cataracts
unexplained corneal or conjunctival injuries particularly in the lower half of the eye.

consider when a child presents with injuries in the absence of trauma or medical explanation
Term
what can occur sometime later after a blunt trauma?
Definition
retinal hemorrhage

this is why you should refer anyone with blunt trauma and a history of floaters.
Term
complications of open globe injury
Definition
endopthalmitis
cataract
in terms of FB, the more posterior the FB is in the globe, the worse the prognosis
Term
signs and symptoms of orbital cellulitis
Definition
eyelid oedema
erythema
proptosis, gaze restriction, diplopia
systemic signs: fever
Term
orbital cellulitis occurs when infection develops in which part of the orbit?
Definition
postseptal orbit
Term
mucormycosis is a rare cause of orbital cellulitis and it is usually fatal. factors such as DKA and neutropenia are present in those affected. what is commonly the presenting feature?
Definition
severe infection of the facial sinuses is the commonest presentation.
Term
when do orbital cellulitis and preseptal cellulitis most commonly occur?
Definition
in the winter months due to more infections of the sinuses from colds and influenza etc
Term
complications of orbital cellulitis
Definition
meningitis
total loss of vision
cerebral abscess
Term
what is chemoses?
Definition
swelling/oedema of the conjunctiva
Term
what ix if you suspect orbital cellulitis?
Definition
CT sinus and orbit +/- brain
Term
mx for preorbital cellulitis

and orbital cellulitis
Definition
preorbital: mx: PO co-amoxiclav or IV ceftriaxone

orbital cellulitis: IV cefotaxime and flucox plus metronidazole if pt is > 10 years and has sinusitis
Term
fluorescin stain and what colour light is used to detect foreign bodies in the eye?
Definition
blue light AKA Wood's light
Term
In fluorescein angiography where is the dye injected by the ophthalmologist?
Definition
into the pt arm
Term
if you wanted to see deeper patterns of circulation than fluorescein angiography was providing which dye test could you use?
Definition
ICG - indocyanine green angiography
Term
which test is used to see if there are ocular leaks from the cornea, sclera or conjunctiva following injury or surgery?
Definition
Seidel test

fluorescein 10% dye injected. then use a cobalt blue light
the leak will appear green
Term
areas of retinal ischema with oedema are AKA?
Definition
cotton wool spots
Term
stages of hypertensive eye disease

severe eye disease changes associated with SBP >220 or DBP >110
Definition
1: silver wiring
2: AV nipping
3: cotton wool spots and superficial haemorrhages
4: papilloedema
Term
complications of hypertensive retinopathy
Definition
optic neuropathy
central vein or central artery occlusions
Term
mx of ocular HTN
Definition
fatty deposits in retinal vessels remain when HTN is rx but retinopathy resolves.
eye changes develop within 48 hours of BP rising and resolve 2-10 weeks of it being lowered.
Term
optic neuritis features
Definition
may be a sign of MS
there is pain in the eye made worse on moving
there are colour changes (dyschromatopsia) particularly red desaturation
RAPD
scotoma
Term
rx for optic neuritis?

ix in optic neuritis?
Definition
methylprednisolone 1g daily for 3 days

do MRI of brain to give information on likelihood of getting MS
Term
eye conditions associated with diabetes
Definition
cataracts
rubeiosis iridis and glaucoma
diabetic retinopathy (DR)
occular motor nerve palsies
Term
after medically dilating the pupil for how long can the pt not drive?
Definition
6 hours afterwards
Term
which agent is used to dilate the eye in diabetic eye exam?
Definition
tropicamide
Term
when should monitoring for DR begin in type 1 and 2 diabetes?
Definition
from 12 years of age annually
Term
managing DR
Definition
glycemic control ideally around 6.5%
BP control 140/80 or 130 if end organ damage
lipid control
Term
how is macular oedema treated
how is retinopathy treated?
Definition
macular oedema: focal laser rx
retinopathy: pan retinal photocoagulation
Term
in clinically significant macular oedema what rx is used as adjunct to focal laser therapy?
Definition
intravitreal steroids e.g.
TRIAMCINOLONE
Term
complications of diabetic retinopathy
Definition
visual loss secondary
macular oedema
macular ischemia
vitreous haemorrhage
tractional retinal detachment
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