Shared Flashcard Set

Details

Exercise Physiology - Chapter 4
Huang-Exercise Metabolism
50
Physiology
Undergraduate 3
02/01/2014

Additional Physiology Flashcards

 


 

Cards

Term
How do we measure energy metabolism?
Definition
measuring VO2
Term
What are the two ways that VO2 is measured?
Definition
Absolute
Relative
Term
Describe absolute VO2.
Definition
the actual amount
expressed in liters per minute
Term
Describe relative VO2.
Definition
the VO2 relative to body weight of an individual
expressed in ml per kg per minute
Term
What is VO2?
Definition
how much oxygen your body consumes every minute
Term
What is your relative VO2 if you weight 100kg and your absolute VO2 is 5L/min?
Definition
50 mL/kg/min
5L = 5000mL
5000/100 = 50
Term
At rest:
(A)what system primarily make ATP?
(B)what are blood lactate levels?
(C)what is resting relative and absolute VO2?
Definition
(A) almost 100% by aerobic systems
(B) less than 1 mM/L
C) 0.25L/min and 3.5 mL/kg/min
Term
What is MET?
Definition
metabolic equivalents
the expression of energy cost for activities in a simple unit
Term
What is one MET equal to at rest?
Definition
1 MET = 3.5 mL/kg/min
Term
What is VO2 max?
How do we measure VO2 max?
Definition
the maximal rate to transport and use oxygen
subject must reach exhaustion
Term
Explain a VO2 max test using a treadmill.
Definition
increase speed until the subject reached 80% of their max heart rate (APMHR).
begin increasing incline 2% every minute until subject reaches exhaustion.
Term
What is the five criteria for addressing a VO2 max?
Definition
1) the plateau in oxygen consumption
2) the attainment of RER=1-1.5 <
3) the attainment of APMHR (220-age)
4) the exhaustion of the subject
5) blood lactate level of 8 mM/L
Term
What are the two sources of CO2?
Definition
metabolism (carb and fat)
hydrogen buffering system
Term
Explain the transition from rest to exercise.
Definition
-ATP production increases immediately
-oxygen uptake increases rapidly
-initial ATP production made through anaerobic pathways
-oxygen deficit
Term
How long does it take to reach a steady state?
How is ATP made after steady state is reached?
Definition
1-4 minutes
aerobic systems
Term
What is oxygen deficit?
Definition
lag in oxygen consumption at the onset of exercise

the difference between the TOTAL OXYGEN ACTUALLY CONSUMED during exercise and the TOTAL OXYGEN REQUIRED (CONSUMED) in steady-rate from start of exercise
Term
How is oxygen supplied at the onset of exercise?
What are the consequences?
Definition
maintained through oxygen stores
ATP-PCr systems
fast glycolysis

the more oxygen borrowed means more recovery time
lactate concentration will be greater the more oxygen borrowed
Term
Explain oxygen deficit in trained individuals.
Definition
have a lower oxygen deficit
they reach a steady state quicker, using less anaerobic systems, producing less lactic acid which means shorter recovery
Term
what is the difference between submax and max testing?
Definition
with submax testing the subject will be able to reach steady state
Term
what is EPOC?
Definition
excess postexercise oxygen consumption

after exercise, oxygen consumption doesn't return to resting levels immediately

aka oxygen debt
Term
What happens in the body during the fast curve component?
Definition
steep decline in oxygen consumption
replenish ATP, PCr, and oxygen stores to 100%
Term
What happens in the body during the slow curve component?
Definition
slow decline in oxygen consumption
elevated HR, breathing, body temp, epinephrine and norepinephrine
conversion of lactic acid to glucose**gluconeogenesis
aka lactate acid phase
Term
explain why EPOC is greater after high intensity exercise.
Definition
higher body temp
greater depletion of PC
greater blood lactate concentrations
higher blood epinephrine/ norepinephrine levels
Term
What happens to lactate during recovery?
Definition
70% oxidized by non working muscle cells
20% reconverted to glucose
10% converted to amino acids
Term
what is the metabolic response to prolonged exercise?
Definition
ATP production primarily from aerobic systems
steady state oxygen uptake can generally be maintained during submax exercise
Term
what is the metabolic response to prolonged exercise in a hot and humid environment or at high intensity?
Definition
upward drift of oxygen uptake over time due to the increase in body temp and rising epinephrine/ norepinephrine levels
a steady state will not be reached
Term
What is the lactate threshold?
what is it also known as?
Definition
the point at which blood lactic acid rises systematically during incremental exercise

anaerobic threshold
onset of blood lactate accumulation (OBLA)
Term
what is bicarbonate buffering?
Definition
non-metabolic CO2 production
helps regulate lactic acid concentrations to delay reaching lactate threshold
Term
What are the four explanations for the lactate threshold?
Definition
1) low muscle oxygen (hypoxia)
2) accelerated glycolysis: NADH is produced faster than it can be moved to the mitochondria, changes pyruvate into lactic acid
3) recruitment of fast-twitch muscle fibers: contains LDH isozyme
4) reduced rate of lactate removal from the blodd
Term
what is the most common LDH isozyme in muscles?
Definition
m4
Term
what are the practical uses for lactate threshold?
Definition
prediction of performance
planning training programs
Term
how many kcal's does 1L of oxygen equal?
Definition
5
Term
what is RER?
Definition
respiratory exchange ratio

an estimate of the primary substrate bring used to make ATP

CO2/ O2
Term
what is the resting RER?
Definition
0.75-0.85
Term
what can RER indicate?
Definition
the type of fuel being used by the cell
fat = 0.7 RER
carbs = 1 RER
Term
how can we use RER to estimate energy expenditure?
Definition
must reach a steady state by sumaximal exercise
Term
what is the RER of an trained and untrained individual?
Definition
trained = 1.5-2.0
untrained = 1.01-1.08
Term
explain protein metabolism during prolonged exercise.
Definition
proteases breakdown protein and may contribute to as much as 5-10% of energy.

12-15% during max effort

proteins play a more important role is providing the enzymes to drive the reactions.

urea is a byproduct
Term
using R value to find kcals.
Definition
estimation of kcals expended, just add 4

can only be done if steady state is reached
Term
example of using RER to find calories:
2.5L/min for 10 minutes with a RER of 0.8, how many calories are expended?
Definition
2.5x10=25
4+0.8=4.8
4.8x25=120kcals in ten minutes
Term
what is the primary fuel of low intensity exercise(<30% VO2 max)?
Definition
fats
Term
what is the primary fuel of high intensity exercise (>70% VO2 max)?
Definition
carbs
Term
explain the crossover concept?
Definition
describes the shift from fat to carbs as exercise intensity increases
Term
what causes the crossover?
Definition
recruitment of fast-twitch muscle fibers causes an increase in glycolytic enzymes
increasing blood levels of epinephrine/ norepinephrine which causes phosphorylase to breakdown glycogen
Term
what is the fuel for low intensity, prolonged exercise?
why?
Definition
shift from carb to fat metabolism
due to the increased rate of lipolysis by lipases activated by epinephrine/ norepinephrine, recruitment of slow-twitch muscle fibers, and aerobic metabolism
Term
discuss muscle glycogen.
Definition
primary source of carbs during high intensity exercise during the first hour of exercise
Term
discuss blood glucose.
Definition
formed in the liver by gluconeogenesis
primary source during low intensity exercise
important during long-duration exercise
Term
discuss intramuscular triglycerides.
Definition
primary source of fat during high-intensity exercise
Term
discuss plasma FFA.
Definition
formed from adipose lipolysis
FFA converted to acetyl-CoA to be used in the Krebs Cycle
primary source of fat during low-intensity exercise
important as muscle triglycerides decline
Term
how is protein supplied during exercise?
Definition
broke down into amino acids and can be converted to glucose in the liver. about 2% of total energy
Supporting users have an ad free experience!