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Exam 5 Systemic Mycoses
Fungi
36
Biology
Undergraduate 3
04/12/2015

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Cards

Term
What is the definition of dimorphic fungi
Definition
Yeast @ 37 (or in tissue)
Mold @ RT (or in nature)
Term
Where can Histoplasma capsulatum be found?
Definition
Worldwide
In U.S.A.: MS & Ohio River Valley
Term
True or False:
Histoplasma capsulatum likes soil enriched with bird manure
Definition
True
Term
How is Histoplasma capsulatum acquired?
Definition
Inhalation of spores
Term
Which MO has 95% of cases as asymptomatic & self limited?
Definition
Histoplasma capsulatum
Term
True or False:
Chronic pulmonary infections with dissemination due to Histoplasma capsulatum can occur
Definition
True
Term
Describe the mold form of Histoplasma capsulatum
Definition
Tuberculate Macroconidia
Teardrop Microconidia
Term
What do you use to identify Histoplasma capsulatum?
Definition
Conversion to yeast phase
Exoantigen test
Nucleic acid probe
Term
What is the Epidemiology of Blastomyces dermatitidis?
Definition
MS, MO, & Ohio River Valley
Canada
Soil & Rotting Wood
Term
What is the disease consistent with Blastomyces dermatitidis?
Definition
Blastomycosis
Term
What are the two routes of acquisition of Blastomyces dermatitidis?
Definition
Usually inhalation
Sometimes cutaneous route
Term
What are the majority of infections of Blastomyces dermatitidis?
Definition
Symptomatic & self-limiting
Term
What type of infection is typed with Blastomyces dermatitidis?
Definition
Respiratory tract infection
Term
Describe the Direct Exam KOH for Blastomyces dermatitidis
Definition
Double Walled Broad Based Budding Yeast (figure 8)
Term
Describe the Microconidia of Blastomyces dermatitidis
Definition
Teardrop shaped
Term
Describe the Macroconidia of Blastomyces dermatitidis
Definition
No Macroconidia
Term
What 3 types of methods are used to identify Blastomyces dermatitidis?
Definition
Conversion to yeast phase
Exoantigen test
Nucleic acid probe
Term
What type of agar is effective in the conversion to yeast phase for Blastomyces dermatitidis?
Definition
Cotton Seed Agar
Term
What is the name of the disease associated with Coccidioides immitis?
Definition
Coccidioidomycosis
Term
What is Coccidioidomycosis also known as?
Definition
Valley Fever
Term
Which MO is attributed to Valley Fever?
Definition
Coccidioides immitis
Term
Which MO can be linked to the following:
60% of cases are asymptomatic & self limiting
Definition
Coccidioides immitis
Term
Describe the Direct exam with KOH for Coccidioides immitis
Definition
Thick walled spherule with endospores
Term
What is the Coccidioides immitis culture considered?
Definition
Lab Hazard
Term
True or False:
Only mold phase of Coccidioides immitis can be grown in lab
Definition
True
Term
Which MO is attributed to the following morphology?
Rectangular or barrel-shaped alternating arthroconidia
Definition
Coccidioides immitis
Term
What is the morphology of Coccidioides immitis?
Definition
Rectangular or barrel-shaped alternating arthroconidia
Term
What are 3 ways, other than morphology, to identify Coccidioides immitis?
Definition
Conversion to yeast phase
Exoantigen test
Nucleic acid probe
Term
Is Conversion to yeast phase practical for Coccidioides immitis?
Definition
No
Term
What is the most virulent of all human mycotic agents?
Definition
Coccidioides immitis
Term
What is the Epidemiology of Paracoccidioides brasiliensis?
Definition
Found in S. America & part of the U.S.A.
Term
What is the Disease associated with Paracoccidioides brasiliensis?
Definition
Paracoccidiomycosis
Term
What type of disease is Paracoccidiomycosis?
Definition
Pulmonary infection
Often disseminates
Term
What are the 3 types of identification methods used for Paracoccidioides brasiliensis?
Definition
Conversion to yeast phase
Exoantigen test
Nucleic acid probe
Term
Describe the yeast phase of Paracoccidioides brasiliensis
Definition
Mariners wheel
Term
Describe the mold phase of Paracoccidioides brasiliensis
Definition
Unadorned conidiophores "fungal lollipops"
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