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exam 5
reproduction, pregnancy, development, genetics
266
Anatomy
Undergraduate 2
05/03/2011

Additional Anatomy Flashcards

 


 

Cards

Term
testes
Definition
male gonads
Term
housing of testes
Definition
external to the abdominopelvic cavity within the scrotal sac
Term
development of testes
Definition
within abdominopelvic cavity but descend through inguinal canal approx. 1-2 months before birth
Term
importance of testical descent
Definition

sperm development

temperature outside is slightly lower than normal boy temperature

Term
division of testes
Definition
about 250 lobules each containing 1-4 highly convoluted seminiferous tubules
Term
seminiferous tubules (lining and function)
Definition

lined with seminiferous epithelium

site of spermatogenesis

Term
seminiferous tubule cell types
Definition

spermatogenic cells

sertoli cells

interstitial cells

Term
spermatogenic cells
Definition
give rise to spermatozoa through mitosis then meiosis
Term
sertoli cells
Definition
supportive cells housed among the spermatogenic cells
Term
interstitial (leydig) cells
Definition
housed outside seminiferous tubules, secrete testosterone
Term
mediastinum testis
Definition
central region containing network of tubes called rete testis
Term
rete testis
Definition
conduct sperm out of testis
Term
male duct system
Definition

epididymus

vas (ductus) deferens

ejaculatory duct

Term
epididymus
Definition

tightly coiled tube emerging from each testis

site of final sperm maturation steps

Term
location of vas (ductus) deferens
Definition
ascends through inguinal canal into abdominopelvic cavity
Term
length of vas deferens
Definition
approx. 18 inches long
Term
function of vas deferens
Definition
stores sperm and propels them into ejaculatory duct via peristalsis
Term
ejaculatory duct
Definition

formed when vas deferens fuses with seminal vesicle

empties into urethra

Term
function of accessory glands of male system
Definition
manufacture secretions that are mixed with sperm to yield semen or seminal fluid
Term
accessory glands of male system
Definition

seminal vesicle

prostate gland

Cowper's or bulbourethral gland

Term
seminal vesicle
Definition

major fluid component of semen (60%)

high sugar solution (fructose) for sperm energy

prostaglandins

Term
prostate gland location
Definition
donut shaped gland that surrounds the upper region of urethra
Term
enlargement of prostate
Definition
can constrict urethra
Term
function of prostate secretion
Definition
makes semen more basic
Term
why must semen be basic
Definition

required for sperm motility

neutralizes acidic vaginal environment

Term
cowper's gland description
Definition

pea-sized gland that empties into middle portion of urethra

stimulated by sexual arousal

Term
Cowper's gland secretion
Definition

neutralizes any urine residue within urethra

precedes ejaculation but can contain many sperm

Term
penis
Definition
male copulatory organ
Term
components of penis
Definition

root

tubular shaft

glans penis

Term
erectile tissues of penis and function
Definition

corpora cavernosa

corpus spongiosum

fill with blood to produce an erection

Term
circumcision
Definition
removal of foreskin which surrounds the glans penis
Term
erection is due to what?
Definition
vasoconstriction of the vessels leaving the penis
Term
nervous control of erection
Definition

parasympathetic control centers in brain and spinal cord

reflex reaction due to touch receptors of the penis

Term
impotency
Definition
inability to achieve erection
Term
origin of impotency
Definition
psychological or medical in origin
Term
2 component of ejaculation
Definition

emission

expulsion

Term
emission
Definition

  • sympathetic nerve impulses to epididymus and vas deferens cause sperm to enter ejaculatory duct
  • fluid from seminal vesicles and prostate mixed with sperm
  • cowpers gland releases semen into urethra

Term
expulsion
Definition
rhythmic contractions of ejaculatory duct expels semen in spurts from urethra; orgasm
Term
hypothalamic hormonal control of male reproduction
Definition
hypothalamus releases GnRH which stimulates release of LH and FSH from anterior pituitary
Term
FSH in male reproduction
Definition
stimulates seminiferous tubule cells to proliferate and respond to testosterone
Term
LH in male reproduction
Definition

stimulates interstitial cells to release testosterone

works with FSH for spermatogenesis

Term
is the hormonal control of the male system a positive or negative feedback system
Definition
negative
Term
how is male reproduction under negative feedback control
Definition

  • inhibin from Sertoli cells inhibits FSH release when the lumen is full of sperm
  • testosterone inhibits GnRH release

Term
description of ovaries
Definition
paired organs approx. 3.5 cm in length
Term
location of ovaries
Definition
suspended in pelvic cavity by suspensory and broad ligaments
Term
functions of ovaries
Definition

production of estrogens and progesterone

 

production of eggs

Term
# of follicles in ovary at puberty
Definition
approx. 400,000
Term
how many follicles actually mature to produce an egg?
Definition
400
Term
oogenesis
Definition

process by which mature oocytes are produced

 

primary follicle → secondary follicle → graafian follicle

Term
ovulation
Definition
fluid build-up in Graafian follicle causes egg to burst out of follicle/ovary
Term
what causes fraternal twins, trips, etc.?
Definition
when more than one graafian follicle bursts
Term
eggless follicle becomes...
Definition
corpus luteum that, if unfertilized, degenerates into corpus albicans
Term
2 components of female hormone production
Definition

developing follicles

corpus luteum

Term
hormone produced by developing follicles
Definition
primarily estrogens
Term
hormone produced by corpus luteum
Definition
primarily prgesterone
Term
2 phases of ovarian cycle
Definition

follicular phase

luteal phase

Term
hypothalamic role in follicular phase
Definition
produces GrNH which causes the anterior pituitary to secretes FSH and LH
Term
FSH in follicular phase
Definition
causes follicle development and release of estrogens
Term
LH role in follicular phase
Definition
increasing levels stimulate ovulation
Term
LH role in luteal phase
Definition
stimulates development of corpus luteum
Term
corpus luteum secretes....
Definition
progesterone
Term
progesterone demonstrates what kind of feedback control over LH production?
Definition
negative
Term
menopause
Definition
stage in life when ovulation no longer occurs
Term
cause of menopuase
Definition
sharp decline in the sensitivity of ovary to gonadotropins (FSH and LH)
Term
side effect of menopause
Definition
decreased production of estrogen
Term
treatment for menopause
Definition
hormone replacement therapy
Term
are oviducts directly connected to ovaries?
Definition
no
Term
fimbriae
Definition
help guide oocyte into lumen
Term
can an egg fall into the abdominal cavity?
Definition
yes
Term
functions of oviduct
Definition

  • moves egg via peristalsis
  • conducts permatozoa from uterus toward oocyte
  • conducts zygote to uterus
  • site of fertilization

Term
the oviduct has what kind of epithelium and why?
Definition
ciliated to aid in the motility of germ cells
Term
ectopic pregnancy
Definition
when ferilized egg implants anywhere other than uterus
Term
most common type of ectopic pregnancy
Definition
tubal
Term
description of uterus
Definition
muscular organ the size and shape of a pear
Term
site of fetal development
Definition
uterus
Term
location of uterus
Definition
suspended in lower abdominal cavity by broad and round ligaments
Term
is the uterus mobile?
Definition
to some degree
Term
3 parts of uterus
Definition

fundus

body

cervix

Term
3 layers of uterine wall
Definition

perimetrium

myometrium

endometrium

Term
perimetrium
Definition

outer covering of uterus

analogous to serosa

Term
myometrium
Definition
thick smooth muscle layer arranged in multiple directions
Term
endometrium
Definition

inner glandular epithelial layer

alternates in growth and death cycles with menstrual cycle

Term

basalis layer of endometrium

2 functions

2 details

Definition

regenerates functional layer

always present

not lost with menstruation

regrows to prep for new possible implantation

Term
functionalis layer
Definition

varies in thickness due to hormonal control

lost during menstruation

Term
proliferative phase
Definition
vascular thickening of endometrium in response to rising estrogen levels
Term
source of estrogen
Definition
growing ovarian follicle
Term

secretory phase

4 characteristics

Definition

maximum thickening of endometrium to form thick glandular layer

ready for implantation

stimulated by progesterone

uterine glands produce thick mucous

Term
uterine and ovarian cycles synchronized by....
Definition
cycling levels of FSH and LH
Term
vagina
Definition

female copulatory organ

birth canal

exit site of menstrual bleeding

Term
vaginal rugae
Definition
folds that allow an increase in diameter during intercourse and birthing
Term
other female external genitalia
Definition

labia

clitoris

Term
composition of vagina
Definition

stratified squamous epithelium and endogenous bacteria

acidic environment

Term
how many sperm are deposited in the vagina
Definition
200-600 million
Term
where in the vagina are sperm deposited?
Definition
near the cervix
Term
why must the sperm pass quickly through the cervix?
Definition
it will be killed by the acidic environment
Term
what must happen to the cervical mucous, why
Definition
thins to allow entrance
Term
when does the cervical mucous thin
Definition
when there are high estrogen levels
Term
when does the thinning of cervical mucous peak
Definition
around the time of ovulation
Term
how many sperm in oviduct after ejaculation?
Definition
100-200
Term
what causes contractions that propel sperm
Definition
prostaglandins from seminal vesicle
Term
when is the swimming action of sperm greatly enhanced?
Definition
within the vicinity of the egg
Term
what aids in dispersement and motility of sperm
Definition
reverse peristalsis of uterus and oviduct
Term
capacitation
Definition
final maturation of sperm that occurs in female tract due to female tract-derived factors
Term
how long does capacitation take
Definition
several hours
Term
process of capacitation
Definition

motility enhanced

thinning of sperm membrane

enzymes exit sperm to degrade oocyte membrane

Term
what happens when the sperm contact the egg
Definition
many begin chewing their way through
Term
many sperm use ___ and begin to penetrate ____
Definition
acrosome, corona radiata
Term
what happens when the first sperm penetrates the zona pellucida?
Definition
a chain of reactions is set off
Term
chain of reactions after penetration
Definition

zona pellucida become impermeable to other sperm to prevent cofertilization

egg completes final stages of meiosis II

Term
what is produced when the sperm and egg combine
Definition
zygote
Term
fertilization
Definition

sperm deposited near cervix

capacitation

contact with egg

migration of zygote through oviduct to uterus

Term
how long is the oocyte viable for after ovulation
Definition
approx 24 hours
Term
how long are spermatozoa viable after ejaculation
Definition
approx 3 days
Term
when must intercourse occur
Definition
between 3 days before and 1 day after ovulation
Term
window for fertilization
Definition
roughly 5 days
Term
where does fertilization occur
Definition
usually in the oviduct
Term
what happens to the zygote before it reaches the uterus?
Definition
undergoes several rounds of cell division
Term
implantation
Definition
attachment of early embryo to uterine endometrium
Term
what stage of development is the embryo at when it reaches the uterus
Definition
morula with 8-32 cells
Term
what stage of development is the embryo at when implantation occurs
Definition
blastula with 100+ cells
Term
outer trophoblast cells
Definition
produce chorion and placenta
Term
inner cell mass
Definition
produces embryo
Term
what does the chorion precursor secrete
Definition
HCG or human chorionic gonadotropin
Term
secretion of HCG
Definition

prevents degeneration of corpus luteum

causes corpus luteum to secrete large levels of progesterone which maintains the uterine endometrium

bypasses progesterone-LH feedback loop

Term
pregnancy tests
Definition
detect HCG with an antibody
Term
urine pregnancy test
Definition
can detect as early as a couple days before missed period
Term
blood pregnancy test
Definition
more accurate than urine test at earlier times
Term
zygote
Definition
fertilized egg with one cell
Term
embryo
Definition
first two months of development
Term
fetus
Definition
third month through term
Term
extraembrionic membranes
Definition

amnion

yolk sac

allantois

chorion

Term
amnion
Definition
innermost membrane that contains amniotic fluid
Term
function of amnion
Definition

provides space

provides thermal/trauma insulation

Term
yolk sac
Definition

first site of RBC production

becomes part of umbilical cord

Term
allantois
Definition
becomes part of umbilical cord
Term
chorion
Definition
contains villi that reach out
Term
predominant villi of chorion
Definition
develops into fetal portion of placenta
Term
origin of fetal portion of placenta
Definition
chorion
Term
origin of maternal portion of placenta
Definition
uterine tissue
Term

origin of umbilical cord portion of placenta

Definition
allantois and yolk sac
Term
functions of placenta
Definition

allow exchange between maternal and fetal blood without physical mixing of blood

 

production of hormones

Term
what passes from maternal blood to fetus
Definition
virtually everything soluble
Term
what passes from fetus to maternal blood
Definition
waste products, primarily carbon dioxide and urea
Term
hormones produced by placenta
Definition

HCG

estrogens

progesterone

lactogen

relaxin

Term
lactogen
Definition
stimulates breast tissues for milk production
Term
relaxin
Definition
relaxes tendons, ligaments, and muscles during late pregnancy
Term
harmful agents that can cross placenta
Definition

teratogens

pathogens

Term
teratogens
Definition

agents that may cause congenital abnormalities or death

alcohol, nicotine, some prescription drugs, etc

Term
german measles
Definition
can cause fetal blindness and/or deafness
Term
toxoplasma gondi
Definition
normally benign but can kill developing fetus
Term
origin of toxoplasma gondi
Definition
cat litter box
Term
syphilis
Definition
can kill fetus
Term
gonorrhea and genital herpes
Definition

infect eyes during delivery

don't cross placenta but can infect during birth

Term
myometrium preparation
Definition

fetal anterior pituitary releases ACTH

fetal adrenal cortex releases cortisol

placenta releases large amounts of estrogens

myometrial cells develop oxytocin receptors

Term
braxton-hicks contractions (false labor)
Definition
myometrium preparation
Term
parturition
Definition
labor
Term
initiation of labor
Definition

fetal posterior pituitary released oxytocin

placenta releases prostaglandins

synergistic effect causes uterine contractions

release of maternal oxytocin

Term
what kind of feedback is the release of maternal oxytocin
Definition
positive
Term
stages of labor
Definition

dilation

expulsion stage

placental stage

Term
dilation
Definition

from onset of labor until cervix dilation is adequate for passage of infants head

 

(approx 10 inches)

Term
effacement
Definition
thinning of cervix
Term
which is the longest stage of labor
Definition
dilation
Term
how long does dilation last
Definition
may last 6-12 hours or more
Term
expulsion stage
Definition

period beginning as the fetal head begins to enter the birth canal

uncontrollable maternal urge to push

Term
crowning
Definition
when largest dimension of baby's head distends vaginal orifice
Term
episiotomy
Definition
surgical incision to widen vaginal orifice
Term
function of episiotomy
Definition
reduces tissue tearing
Term
placental stage
Definition

necessary to reassemble placenta

any pieces left would result in uncontrollable maternal bleeding

also count placental blood vessels

Term
why count placental blood vessels
Definition
abnormalities associated with certain fetal cardiovascular birth defects
Term
role of placental hormones in lactation
Definition

prepare breasts during late pregnancy

colestrum production

Term
when does milk production begin
Definition
approx 3 days after birth
Term
suckling reflex
Definition
mammory cells contract to expel milk in a positive feedback loop until sucking stops
Term
what does the suckling reflex dampen
Definition
hypothalamic release of GnRH
Term
what does dampened release of GnRH result in
Definition

ovarian and uterine cycles not immediately re-established

makes it more difficult to become pregnant

Term
length of prenatal period
Definition
approx 38 weeks
Term
cleavage
Definition
from first mitotic division until 2 weeks post fertilization
Term
vegetative cleavage
Definition
cell division without an increase in total mass
Term
morula
Definition
solid ball of 16-32 cells
Term
blastula
Definition

ball of cells develops fluid-filled core

contains inner cell mass and trophoblasts

Term
embryonic stage
Definition
weeks 2-8
Term
most important time of development
Definition
embryonic stage
Term
what is developed during embryonic stage
Definition

placenta

major internal organs

external body structures

Term
gastrula
Definition

early structure within embryonic stage

three primitive germ layers from which all tissues are derived

Term
ectoderm
Definition
nervous tissue, epidermis, lining of mouth and anus
Term
mesoderm
Definition
muscle tissues, connective tissues, blood and lymphatic vessels, internal reproductive organs, kidneys, serosal linings
Term
endoderm
Definition
epithelial lining of bladder, urethra, digestive, and respiratory tracts
Term
fetal stage
Definition

ninth week through birth

period of rapid growth plus significant changes in proportional sizes of body parts

Term
fetal circulation
Definition

significant differences from adult circulation

umbilical veins

umbilical arteries

right to left shunts

Term
umbilical veins
Definition
carry 50% oxygenated blood from placenta to liverand 50% to ductus venosus
Term
what does the ductus venosus empty in to
Definition
inferior vena cava
Term
right to left shunts
Definition
allow blood to bypass pulmonary circulation
Term
foramen ovale
Definition

shunts blood from the right atrium to the left atrium

will close after birth and become fossa ovalis

Term
ductus arteriosus
Definition
shunts blood from the pulmonary trunk to the aorta
Term
umbilical arteries
Definition
branch off the internal iliac arteries and return oxygen-poor blood to the placenta
Term
neonatal period
Definition
first four weeks following birth
Term
neonatal change in respiratory system
Definition
inflation of lungs
Term
first breath
Definition

forceful due to significant sympathetic response to the birthing process

breathing much easier after initial breath

Term
neonatal urinary system
Definition

unable to produce concentrated urine

requires relatively large amounts of water

Term
what do the umbilical veins become
Definition
ligamentum teres
Term
what do the proximal portions of umbilical arteries become
Definition
superior vesicular arteries that supply blood to bladder
Term
what do the distal portions of umbilical arteries become
Definition
lateral umbilical ligaments
Term
why does the foramen ovale close
Definition
due to increase pressure in left atrium
Term
fossa ovalis
Definition
fusion of foramen ovale with cardiac tissue within one year after birth
Term
what does the ductus arteriosus become
Definition
ligamentum ateriosus
Term
human genetics
Definition
study of the mechanism of the body
Term
Chromosomes are composed of what
Definition
DNA
Term
location of DNA
Definition
nucleus
Term
what does DNA usually disperse into
Definition
chromatin
Term
what does chromatin condense into before cell division
Definition
visible chromosomes
Term
how are chromosome arranged
Definition
23 pairs of diploid homologs
Term
autosomes
Definition

chromosomes 1-22

homologous

Term
sex chromosomes
Definition
X and Y
Term
XX
Definition
female
Term
XY male
Definition
Term
karyotype
Definition
alignment of all chromosomes from cell to analyze
Term

each cell contains ___

each cells espresses ____

Definition

identical chromosomes

a certain group of genes

Term
gene
Definition

region of chromosome that codes for one protein

different cells express different genes

unit of inheritance

Term
types of cell divison
Definition

mitosis

meiosis

Term
mitosis
Definition
a diploid mother cell divides to form 2 identical diploid daughter cells
Term
meiosis
Definition
one cell divides twice to produce 4 haploid cells (gametes)
Term
gametes
Definition
spermatozoa and oocyte
Term
spermatogenesis
Definition
4 sperm produces from each germ cell following meiosis
Term
how often does spermatogenesis occur
Definition
million of times daily in a healthy post-pubescent male
Term
oogenesis
Definition
each germ cell yields 1 egg and 3 nonfunctional polar bodies
Term
where is oocyte arrested until puberty
Definition
meiosis I
Term
where is oocyte arrested during follicle maturation until fertilization
Definition
meiosis II
Term
when does the oocyte complete meiosis
Definition
when (if) it becomes fertilized
Term
what do genes control
Definition
characteristics of an individual
Term
how are genes arranged
Definition
in a linear fashion along length of chromosomes
Term
alleles
Definition
each gene is present twice
Term
dominant allele
Definition

will always be expressed when present

denoted with capital letter

Term
recessive allele
Definition

only expressed if dominant allele is absent

denoted with lower case letter

Term
homozygous
Definition

both alleles are the same

two dominant or two recessive

Term
heterozygous
Definition
both alleles are different
Term
genotype
Definition

what alleles are present

actual genetic composition

Term
phenotype
Definition

what alleles are expressed

actual visal characteristics

Term
complete dominance
Definition
traditional dominant-recessive inheritance
Term
ex of complete dominance
Definition
cystic fibrosis
Term
codominance
Definition

when two alleles are equally expressed

both alleles are presnet and visible

Term
example of codominance
Definition
A and B blood antigens
Term
imcomplete dominance
Definition
when two alleles are equally expressed but result in a blended phenotype
Term
ex of incomplete dominance
Definition
familial hypercholesterolemia
Term
polygenic inheritance
Definition
two or more different genes control the same trait
Term
ex of polygenic inheritance
Definition
skin color
Term
complex traits
Definition
multiple genes and environmental factors all control a trait
Term
ex of complex trait
Definition
height
Term
multiple alleles
Definition
when a trait is controlled by more than two alleles of a single gene
Term
ex of multiple alleles
Definition
ABO blood group
Term
autosomal mode of inheritance
Definition
gene that determines trait is on an autosome
Term
sex-linked inheritance
Definition
gene that determines trait os on the X chromosome
Term
Y chromosome
Definition

contains very few genes

genetic diseases are very rare

Term
x linked inheritance
Definition

traits not necessarily related to gender

many non-gender genes on X

recessive traits always expressed in males

always inherited from mother

Term
autosomal recessive disorders
Definition

cystic fibrosis

tays sachs disease

PKU

Term
cystic fibrosis
Definition
mucous of lungs and GI tract too thick which impedes function
Term
most common inherited human disease
Definition
cystic fibrosis
Term
tay sachs disease
Definition
progressive neurological disorder resulting in death before age 5
Term
who is Tay Sachs most prevalent in
Definition
Jews of Eastern European descent
Term
phenylketouria
Definition
unable to metabolize the amino acid phenylalanine which causes a build up of byproduct that causes irreversible brain damage
Term
when is PKU tested for
Definition
during newborn screening
Term
treatment of PKU
Definition
limited protein intake during childhood
Term
autosomal dominant disorders
Definition

huntington's

achondroblastic dwarfism

Term
huntington's disease
Definition
progressive neurological disorder with onset late in life
Term
achondroblastic dwarfism
Definition
long bones of body fail to grow in length
Term
x-linked disorders
Definition

red-green color blindness

hemophilia

duchenne muscular dystrophy

Term
hemophilia
Definition
unable to clot properly
Term
duchenne muscular dystrophy
Definition
wasting away of muscle with death around age 20
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