Term
when should memantine be perscribed?
why |
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Definition
in late sages of AD
-greatest effiacy is improving cogntiion or minimizing beahvior disturb |
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Term
| since mementine MOa is diff form toher AD meds, what is another place in therapy for it? |
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Definition
| in combo with cholinesterase inhibitors |
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Term
| mementaine, how well does it work? |
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Definition
| ther is small pop of responders, but when it works it works BIG to help functional and behavioral status |
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Term
| *there are no characteristics to predict reposne to memantimine |
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Definition
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Term
| how long do you use memantine:? |
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Definition
| case basis, only know effects short term but long term it cna be sueful to help behaviroal effects |
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Term
| how do chol inhibtors make AD better? |
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Definition
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Term
| how mnay ppl respong to chol inhibit |
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Definition
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Term
| when do you think a pt isnt repsonding to chol inhibitor |
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Definition
| if decline at pre-tx rate 6 mo after drug therapy intitated |
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Term
| due to 200 jouinral articel pointing out chol inhbitor may nto lead to less instutionalization formularies wanted to stop putitng them on- the things aginst this- |
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Definition
journal was underpowered
severity of cognition is not preidcitor of instituitionalization
cost effecigvenss only done with QALY |
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Term
| *there are no predictors of response to chol inhibitors |
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Definition
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Term
| fro chol inhibitors, it is ont wheter to tx or not tx- it is whether to cont tx after 6 onths of trying it |
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Definition
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Term
| whihc chol inhibitor is best? |
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Definition
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Term
| if pt on other chol inhibitor, if becomes mod-sev do they ahve to swtich to Aricept? |
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Definition
| no, can stay on other med evnen tho tis for mild-mod |
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Term
| what is theraputic dose of donepezil? |
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Definition
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Term
| how high do you push chol inhibiotrs |
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Definition
| to max recocmended if possible |
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Term
| *a lto fo time chol inhbitors start at initial dose and dont titrtae, this is what pharmacists can help with |
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Definition
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Term
| when d/c the chol inhbit take into effect can cause irreversible deffect loss, but also very expensive |
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Definition
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Term
| what is the counsel point on chol inhb and agitation |
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Definition
| wait 4 wks, only then change to diff med if still have it |
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Term
| ppl that get chronic chol inhibitors seems to have lower prevelance of beahviro problems |
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Definition
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