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Exam 4
N/A
28
Microbiology
Undergraduate 4
05/18/2013

Additional Microbiology Flashcards

 


 

Cards

Term
Normal Flora
Definition
Microorganisms that colonize a person or an animal usually without causing disease
Term
Infection
Definition
Invasion and growth of pathogens resulting in tissue injury caused by the activites of the pathogen or host immune responses
Term
Disease
Definition
Impairment of body structure or function causing a specific set of signs and symptoms
Term
Communicable disease
Definition
Caused by a pathogen
Term
Noncommunicable disease
Definition
Caused by a genetic or degenerative process
Term
Opportunistic pathogens
Definition

Require a special circumstance to produce disease

 

One opportunistic pathogen will cause a variety of infections

 

Commonly encountered organisms or ones that you carry with you

Term
True pathogens
Definition

Able to infect a healthy host under their own power to initiate disease

 

Usually cause one specific disease

 

Not commonly encountered and are not carried with you

Term
What are the adherence factors of a pathogen?
Definition

capsule

 

fimbriae

 

surface receptors

 

hook

 

viral spikes

 

host cell actin fibers

Term
Exotoxins
Definition

Released from live bacteria

Come from Gram (+) & Gram (-) bacteria

Made of proteins

more toxic than endotoxins

have specific effects on host

heat sensitive

antigenic (stimulates an immune response)

Term
Endotoxin
Definition

Released from dead bacteria

Come from Gram (-) bacteria

Made of lipopolysaccharides

Less toxic than exotoxins

Have generalized effects on host

Not heat sensitive

Not antigenic

Term

Reservoir

 

Definition
The source of the pathogen (where it multiplies) ex. human, animals, water ect.
Term
Portals of exit
Definition

Where and how a pathogen leaves an infected host

ex. skin, blood, urine, ect.

Term
What are the 3 transmission modes
Definition

1. Contact

 

2. Vehicle

 

3. Arthropod vector

Term
What are the 3 types of contact?
Definition

1. Direct contact= physical contact between reservoir and new host. ex kissing, sex, petting an animal

 

2.Indirect contact= transmission through fomite (contaminated, inanimate object)

 

3. Droplet infection= salivary or respiratory discharges in the air that travel less than 1 meter

Term
Vehicle
Definition

Nonliving carrier of an infectious agent

ex. food,water,blood

Term
Arthropod vector
Definition
A living organism that carries and transmits a pathogen from one host to another
Term
Parenteral
Definition
A pathogen enters a host through breakages in skin and mucous membranes
Term
Portals of entry
Definition

Where/how pathogen enters the body of a new host

ex. skin, mucous membranes

Term
Common vehicle
Definition

If more than one case is traced back to the same source

ex. if more than one person gets food poisoining from the same restaurant

Term
Nosocomial infection
Definition
Infections you get from a hospital or a healthcare setting
Term
What are the sources of a nosocomial infection?
Definition
Transmitted through patients, hospital staff, and contaminated objects
Term
Infective dosage
Definition
Actual number of cells of a particular pathogen that is required to overcome the host defenses and initiate infection
Term
What are the stages in the course of a disease?
Definition

1. Infections=pathogen enters host, overcomes host defenses and initiates the course of the disease

 

2. Incubation period=time between infection and appearance of first symptoms

 

3. Prodromal period= appearance of nonspecific symptoms

 

4. Period of illness= appearance of obvious, specific symptoms

 

5. Convalescence period= recovery from illness

Term
Which stages are most contagious and why?
Definition
The last half of incubation period and the prodromal period because with a set of nonspecific symptoms people don't know they are sick and they are infecting others
Term
What are the 3 levels of recovery?
Definition

1. Recovery with immunity=lifelong immunity, good chance you won't get the disease again

 

2. Recovery without immunity= may have the same disease again

 

3. Recovery as a carrier of the pathogen= no symptoms, acts as a reservoir

Term
Chronic disease
Definition
Slow onset, long duration: months or years
Term
Acute disease
Definition
Rapid onset, short duration: days or weeks
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