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Exam 3
Disorders of Female/Male Canine Repro tract
124
Veterinary Medicine
Professional
10/21/2016

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Term
When do silent heats most often occur in dogs?
Definition
-highest incidence in pubertal bitches
Term
What is a silent heat?
Definition
-absence of proestrus-estrous behavior or ntoable clinical signs
-normal physiologic and cytologic (vaginal) estrus
Term
When do split or false heats most common occur in dogs?
Definition
-highest incidence in pubertal bitchs
Term
What is a split/false heat?
Definition
-exhibits behavioral signs of tru proestrus=estrus
-after a few days, the proestrus-estrus signs recede
-true estrus begins several more days or weeks
-ovulation does not occur in the first part of the split heat but it occurs in the second part of the spit head
-conception can occur if the bitch is bred during the true heat
Term
Are LH levels increased or decresed in animals with no gonads? Why?
Definition
-increased
-no feedback to pituitary gland
Term
If a shelter animal comes in wiht high levels of LH, what assumption can we make?
Definition
-no gonads are present
Term
If a shelter animal comes in without a history and has no AMH/Inhibin, what can we assume?
Definition
-no ovaries
Term
How is Brucella canis transmitted?
Definition
-contagious through mucous membrane contact iwht organism
Term
What clinical signs are seen with B. canis infection?
Definition
-abortion: due to placentitis
-iorchitis/epididymitis
Term
How do we diagnose Brucella canis?
Definition
-culture of organism = absolute confirmation
-Rapid Slide Agglutination test
-Tube Agllutination test
-Agar Gell immunodiffusion test: cell surface and cytoplasmic Ag tested
-PCR is now available by some labs
Term
When do we see false negatives with B. canis?
Definition
-early in disease process <4-6 weeks after treatment
Term
When do we see false positives with B. canis?
Definition
-lack of specificity of tests
-cross-reactivity with other antigens
Term
If we get a positive result with routine B. anis screen then what do we do?
Definition
-AGID or PCR to rule out false positive
Term
If we have positi9ve clinical signs attributed to B. canis what do we do?
Definition
-blood or discharge cultures
Term
If we get a negative on routine screen for B. canis, what do you do next?
Definition
-no other test needed
Term
If we get a negative with clinical signs attributable to B. canis what do we do next?
Definition
-3 onthly tests required to rule out false negatives
Term
What are the primary clinical signs seen with canine herpesvirus?
Definition
-neonatal deaths primarily
Term
Is canine herpesvirus temperature sensitive? Where is it found in the body?
Definition
-yes
-thus found in oronasal pharynx
Term
In regards to canine herpesvirus clinical signs, no illnes is seen in animals over ___ weeks of age.
Definition
-3
Term
What is the "critical window" of canine herpesvirus?
Definition
-last thre weeks of pregnancy in a naive bithc up to the first three weeks of neonatal life
Term
Is there a clinical issue if a bitch is exposured to canine herpesvirus during breeding? What if exposed 2-3 weeks postpartum?
Definition
-no
-and no
Term
What are the clinical signs of canine herpes seen in the affected pups?
Definition
-crying, greenish stool, abdominal pain
Term
What is the mortality due to canine herpes in affected pups?
Definition
-near 100%
Term
What is seen on necropsy of a pup who died due to canine herpesvirus?
Definition
-mottled kidneys
Term
What specifics do we aim for with canine whelping areas?
Definition
-out of trafic patterns
-whelping box with pig rails for giant breeds
-acclimate bitch to the area one week prior to due date
-washable bedding with good footing
Term
What do we do if we are confronted with hemorrhagic vaginal discharge during pregnancy?
Definition
-evaluate cytology and vagioscopy
Term
What are the potential causes of hemorrhagic discharge during pregnancy?
Definition
-could be normal
-signs of impending abortion
Term
What are the potential causes of purulent vaginal discharge during pregnancy?
Definition
-pyometra
-dead fetus
Term
In general, how do we treat a bitch that presents with unusual vaginal discharge during pregnancy?
Definition
-give flouroquinolones if necessary
-rest
-supportive therapy as needed
-give P4 if impending abortion
Term
What is the best method to confirm fetal wastage?
Definition
-ultrasound
Term
What are the potential causes for fetal wastage?
Definition
-trauma
-heat stress
-luteal insufficiency
-viral bacteria
-CEH
-protozoa
Term
How do we treat fetal wastage?
Definition
-evacuation of uteirne contents if all babies are dead via PGF2a
Term
Is uterine torsion common in the bitch?
Definition
-uncommon
Term
How does uterine torsion clinically present?
Definition
-acute abdomen pain and distress
-may be asymptomatic until dystocia
Term
How do we diagnose uterine torsion in the bitch?
Definition
-exploratory laparotomy
Term
What occurs in the body at the initiation of parturition in the bitch?
Definition
-progesterone falls rapidly
-transient drop in body temp
-milk evident in glands 1-7 days prir
Term
What initiates the first stage of parturition? What occurs hormonally during this stage?
Definition
-begins after progesterone drops
-removal of progesterone block from uterus = myometrial activity begins
-inc in oxytocin receptor sites
Term
What occurs behaviorally during the first stage of parturition?
Definition
-nesting
-anxiety
-anorexia
Term
What occurs during the second stage of parturition?
Definition
-active contractions: fetus in pelvic canal stimulates urge to push
-amnion appears first
-Ferguson reflex occurs
-greenish-black discharge
Term
What is the Ferguson reflex (occurs during stage II parturition)?
Definition
-oxytocin release and abdominal contractions
Term
During patrutition, delivery of what part of the animal is the greatest effort?
Definition
-the head
Term
Are breech presentations normal in the bitch?
Definition
-yes
Term
What is the breenish-black discharge that shows up during the second stage of parturition in the bitch?
Definition
-uteroverdin
Term
What happens to the canine placenta after parturition?
Definition
-dam eats it
Term
How long does stage II parturition last in the bitch?
Definition
-30 mins to 1 hour
Term
What are the criteria for intervention during stage II parturition in the bitch?
Definition
-active contactions for > 1 hour
-rest period > 4 hours
-black thick discharge without fetus
Term
What diagnostic tool do we use to determine fetal viability in the bitch?
Definition
-ultrasound
Term
What diagnostic tool do we use to determine the presence of additional fetuses in the bitch?
Definition
-rads
Term
What occurs during the third stage of parturition?
Definition
-passage of placentas
-most are passed immediately following fetus
Term
Is placental retention rare or common in the bitch?
Definition
-rare
Term
In which situation is oxytocin absolutely not necessary in the post-parturient bitch to assist in passage of the placentas?
Definition
-if suckling puppies/kittens are present
Term
Describe the time frame, color changes, and consistency changes of normal involution of the bitch.
Definition
-msot expelled in first two weeks
-changes in color: red to brown
-changes in consistency: watery to mucoid
-no odor
-lasts 4-6 weeks
Term
How do we manage the post-parturient bitch?
Definition
-monitor mammary glands and vulvar discharges daily
-unlimited food and water to dam
-start weaning process at 3-4 weeks by offering grueal and complete by 5-8 weeks
-reduce food to dam at weaning
-pressure in glands, signal to quit
Term
How do we manage newborn canines after birth?
Definition
-need colostrum and daily milk intake
-eat, sleep, and dream
-dam stimulates urination/defection
-crying indicates a problem
-poikilothermic for first 2-3 weeks
Term
What are the ambient temp recommendations for the first 30 days of a puppy's life?
Definition
-Days 1-7: 85-90F
-8-28 days: 80F
-29+ days: 70-75F
Term
What do "pig piles" indicate?
Definition
-cold babies
Term
What is the typical daily weight ain in a newborn puppy?
Definition
-10% of birth weight daily
Term
What are the important factors when monitoring neonatal canines?
Definition
-hypothermia: MOST IMPORTANT
-hypoglycemia due to inadequate caloric intake
-hypovolemia due to dehydration
Term
What is metritis?
Definition
-inflammation of the entire uterus (endometrium + myometrium)
Term
What are the clinical signs of metritis?
Definition
-fever
-depression
-purulent vulvar discharge
Term
How do we diagnose metritis?
Definition
-CBC
-vaginal cytology
-culture
-US
Term
HOw do we treat metritis?
Definition
-PGF2a to evacuate the uterus
-supportive therapy: fluids and antibiotics
Term
What are the clinical signs of mastitis?
Definition
-enlarged, hot, painful glands
-fever, leukocytosis
Term
What organisms commonly cause mastitis in the bitch?
Definition
-coliforms, strep, staph
Term
How do we treat mastitis in the bitch?
Definition
-hot pack and strip abnormal milk
-NSAIDs and antibiotics
Term
Does mastitis reoccur in the bitch?
Definition
-yes with subsequent litters or pseudopregnancies
Term
What is the common name for post-partum hypocalcemia?
Definition
-eclampsie
Term
Which canines are most commonly affected by eclampsie?
Definition
-small nervous breeds
-can be hereditary in some lines
Term
What are the clinical signs of canine eclampsia?
Definition
-panting
-pacing
-muscle tremors
-ataxia
-hyperthermia
-tonic-clonic convulsions
-death
Term
How do we treat hypocalcemia?
Definition
-IV calcium gluconate to effect
-oral calcium maintenance
-weaning if the pups are old enough or if unable to control clinical signs
Term
What is SIPS?
Definition
-Subinvolution of placental sites
Term
What are the clinical signs of SIPS in the bitch?
Definition
-persistent uteirne bleeding
-usually ID'd if bleeding persists after weaning
Term
What are the gross lesions seen with SIPS in the bitch?
Definition
-erosions in endometrium
Term
What histologic lesions are seen with SIPs in the bitch?
Definition
-multinuclear giant cells = trophoblast cells
Term
How do we treat SIPS in the bitch?
Definition
-usually self-limiting but we can give PGF2a
Term
What are the clinical signs of puppy vaginitis? When does it usually resolve?
Definition
-small aount of purulent discharge in prepubertal bitch
-goes away with first estrus
Term
What canines are usually affected by adult onset vaginitis?
Definition
-spayed bitches
Term
HOw do we treat adult vaginitis in the bitch?
Definition
-hormonal: DES to thicken vaginal epithelium
-surgery: removal of excess skin folds around vulva
Term
What are the potential causes of vaginal prolapse in the bitch?
Definition
-estorgen-related: proestrus or late pregnancy
-breed
-spay
Term
How do we treat vaginal prolapse in the bitch?
Definition
-treat symptoms
-self-resolving
Term
When during the estrous cycle do pyometras occur in the bitch? In the queen?
Definition
-diestrus (progesterone phase)
-occurs anytime in the queen
Term
Which bitches are most commonly affected by pyometras?
Definition
-older bitches
Term
How do we treat pyometras in the bitch?
Definition
-spay
Term
What is the clinical presentation of pyometra in the bitch?
Definition
-depression: most often seen with toxemia
-leukocytosis: amy see left shift
-vulvar discharge: if open cervix
-PU/PD: endotoxins from E. coli
Term
How do we diagnose pyometra in the bitch?
Definition
-abdominal palpation
-rads
-US
Term
What is the peak age of fertility in the dog?
Definition
-2-4 years of age
Term
What are the important parts of a repro history in the dog?
Definition
-reason for exam
-allprior breedings
-libido and mating ability
-all prior semen evaluations
-previous health problems
-pedigree if needed
Term
What do we palpate for indication of Brucella canis infection on a male dog?
Definition
-testicles and epididymes
Term
What is the accessory gland in the male dog? Does it change over time? What hormone is it dependent on?
Definition
-prostate
-increases with age
-development dependent on testosterone
Term
How do we examine the prostate in a male dog?
Definition
-digital palpation per rectum
-abdominal palpation
-US
-rads
Term
What is the function of 5-alpha reductase? Where does this occur?
Definition
--converts testosterone to the biologically active form dihydrotestosteroone
-in the prostate
Term
What is the purpose of prostatic fluid in the male dog? What does it look like? Normal pH?
Definition
-contributes volume to ejaculate (third fraction)
-looks like water
-normal pH 6.5-6.8
Term
What four characteristics do we evaluate on prostatic fluid?
Definition
-color
-pH
-cytology
-quantified bacterial culture
Term
Which canines are affected by bening prostatic hyperplasia (BPH)
Definition
-incidence increases with age
Term
What clinical signs do we usually see with a dog with BPH? What about in severe cases?
Definition
-often no clinical signs
-Severe cases: rectal compression leads to constipation and ribbon stools without urinary tract signs
Term
What are the clinical signs of abacterial prostatitis in the dog?
Definition
-blood from prepuce or in urine
-nonpainful on palpation
-glood inejaculate
Term
How do we treat BPH and abacterial prostatitis in the dog?
Definition
-5-alpha reductase inhibitors for 6-8 weeks and repeat as needed
-frequent ejaculation
-castration for permanent resolution
Term
What is the most common presentation of bacterial prostatitis? What clinical signs can we see?
Definition
-acute or chronic but usually asymptomatic
-can cause recurrent UTIs
Term
How do we diagnose bacterial prostatitis?
Definition
UA and urine culture
-cytology and culture of prostatic fluid
Term
How do we treat bacterial prostatitis in the dog?
Definition
-antimicrobials that pass BPB (CAP, enrofloxacin, TMS) for 6-8 weeks
-concurrent treatment with a 5-alpha reductase inhibitor
Term
What causes paraprostatic cysts in the dog?
Definition
-embryologic vestiges
Term
What causes intraprostatic cysts in the dog?
Definition
-BPH distorting anatomy
Term
What causes retention prostatic cysts in he dog?
Definition
-blocked ducts
Term
How do we treat prostatic cysts in the dog?
Definition
-larger ones may require surgery
-csastration to reduce testoserne levels or use 5-alpha reductase inhibitors
-rule out bacterial involvement )abscess vs cyst)
Term
What causes prostatic abscesses in the dog?
Definition
-bacterial infection or prostatic cysts
Term
How does a dog with prostatic abscesses appear clinically? Prognosis?
Definition
-systemically ill
-guarded to poor prognosis
Term
What are common sequelae seen prostatic abscesses in the dog?
Definition
-peritonitis
-sepsis
-shock
Term
How do we treat prostatic abscesses in the dog?
Definition
-surgical drainage
-antimicrobials
-castration or 5-alpha reductase inhibitors to reduce prostatic tissue mass
Term
What is the most common prostatic neoplasia seen in the dog/
Definition
-adenocarcinomas
Term
What are the clinical signs of prostatic neoplasia in the dog?
Definition
-stanguria
-dysuria
-more aggressive in neutered animals
Term
True or False: Early castration of the dog protects against prostatic neoplasia.
Definition
-FALSE
Term
Which dogs are most usually affected by prostatic neoplasia?
Definition
-medium to large breeds
-older animals
Term
How do we diagnose prostatic neoplasia?
Definition
-prostatic cytology: ejaculate cytology or FNA
Term
How do we treat prostatic noeplasia in the dog?
Definition
-cure in unlikely with aggressive tumors
-metastasis early
-prostatectomy: urinary icontinence
-msot dogs are euthanized shorty after diagnosis
Term
Describe the prep work for semen collection in the dog.
Definition
-manual collection
-use of a teaser bitch may aid in collection
-good footing
-allow to urinate and defecate prior to attempted collection
-keep distractions at a minimum
Term
What equipment do we need to collect semen form a dog?
Definition
-minimal
-collection tue with or tihout a colelction cone
-baby bottle liners: cheap, sterile, disposable
Term
What are the fractions of ejaculate in the dog?
Definition
-first fraction: presperm
-second fraction: sperm-rich
-third fraction: postsperm and prostatic fluid
Term
What color are all of the fractions of ejaculate in the dog?
Definition
-presperm: slightly cloudy
-sperm-rich: grayish white
-postsperm: crystal clear
Term
How do we evaluate motility in canine ejaculate?
Definition
-evaluated quickly
-place on warmed slide
-gross motility: 10 X
-idnividual motility: 40X
-look for progressive linear movement
Term
HOw do we evaluate morphology of canine ejaculate?
Definition
-stain a sampl of semen to look at individual cells
-always evaluate under oil immersion
-classify 100 cells as either normal or abnormal
Term
What is the norma sperm concentration for a dog? What about in a toy breed?
Definition
-200 million sperm per ejacualte
-toy breed = 50 million per ejaculate
Term
What are the general principles of semen cytology in the dog?
Definition
-stain with modified Wright's stain
-note presence of RBCs, WBCs, and epi cells
-evaluate prostatic fraction separately
Term
What is the gold standard for concentration of ejaculate in the dog?
Definition
-hemacytometer method
Term
What are the organisms that are considered normal flora on the penis/prepuce/urethra?
Definition
-Pateurella
-Staph
-Strep
-Mycoplasma
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