Term
| Eukaryotes-DNA replication occurs in the what phase of cell cycle ? |
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Definition
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Term
| What helps control level of supercoiling in bacteria ? |
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Definition
| DNA gyrase -bacterial topoisomerase |
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Term
replication unit
is a region replicated from 1 origin |
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Definition
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Term
| What contains RNA molecule that serves as a primer for the elongation of DNA ? |
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Term
| Telomerase most active in ? |
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Definition
| embryonic stem cells and cancer cells |
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Term
| The progressive loss of DNA at telomere may indicate what ? |
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Definition
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Term
| somatic cell will stop dividing once its telomeres are |
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Term
what is-inheritable traits that are NOT derived from DNA sequence information
Information dictating extent of chromosome packaging can be transmitted via histones to daughter cell |
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Definition
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Term
| what conversion of one allele into another by recombination & DNA repair |
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Definition
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Term
| When recombination occurs via Holliday junction formation, mismatched single stranded DNA can be recognized by what ? |
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Definition
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Term
DNA repair enzymes will randomly choose one strand (m+) as the correct strand, and replace the opposite strand (m) using m+ as template
Remember that these processes working in what cell division further increase types of gametes produced |
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Definition
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Term
| eukaryotes have DNA that is extensively bound by proteins called ____, which package the DNA in units called ______ |
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Definition
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Term
| what is- non-specific DNA binding proteins, very + charged - many basic Lysine and Arginine residues these neutralize the negative charge of the PO4- DNA backbone |
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Definition
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Term
| Histones are unique, synthesized during what phase of cell cycle ? |
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Definition
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Term
| Histone what facilitates tighter packaging of nucleosomes into a 30 nm chromatin fiber |
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Definition
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Term
| transcriptionally active DNA-beads on string many genes expressed, lacks repetitive sequences display condensation-decondensation cycling in dividing cells |
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Definition
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Term
tightly packaged with proteins 30nm fiber
-transcriptionally inactive contain more repetitive sequences |
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Definition
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Term
| constitutive heterochromatin that binds to kinetochore & mitotic spindle during mitosis and meiosis |
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Definition
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Term
| catalyze ATP-driven separation of DNA after initial denaturation created by other proteins |
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Definition
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Term
| makes short RNA primers that are required for DNA synthesis |
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Definition
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Term
| RNA primer removed by 5’3’ exonuclease activity of DNA Pol 1 or 3 ? |
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Definition
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Term
| required to catalyze final phosphodiester bond sealing okazaki fragments together |
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Definition
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Term
| DNA polymerases require an ________to initiate DNA synthesis |
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Definition
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Term
| DNA pols have proofreading ability, via a |
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Definition
| a 3’5’ exonuclease activity |
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Term
| what kind of bond link nucleotides along single strand of DNA or RNA |
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Definition
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Term
| What bondconnecting a base-pair with deoxyribose are not directly opposite each other, leads to major and minor grooves |
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Definition
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Term
| The presence of an extra of what group on RNA makes RNA much more vulnerable to base-catalyzed hyrdolysis. |
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Definition
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Term
| RNA viruses that replicate through a DNA intermediate (HIV) |
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Definition
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Term
| Eukaryotic genomes contain many noncoding sequences, which include |
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Definition
| introns and repetitive sequences |
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