Term
| the heme part of hemoglobin= |
|
Definition
|
|
Term
| the globin part of hemoglobin= |
|
Definition
|
|
Term
| when hemoglobin bounds to oxygen it becomes? |
|
Definition
|
|
Term
| once oxygen is released in tissues hemoglobin becomes? |
|
Definition
| deoxyhemoglobin (empty hemoglobin) |
|
|
Term
|
Definition
| the daily loss or destruction of aged RBC |
|
|
Term
|
Definition
|
|
Term
| RBC life span equine and ovine |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
Average size of RBC canine
|
|
Definition
|
|
Term
| Average size of RBC feline |
|
Definition
|
|
Term
| Average size of RBC equine |
|
Definition
|
|
Term
| Average size of RBC bovine |
|
Definition
|
|
Term
| which species is known for poikilocytes |
|
Definition
|
|
Term
| which mammal has RBCs similar in shape to avian? |
|
Definition
|
|
Term
| 5 properties to evaluate when looking at RBC morphology |
|
Definition
cell arrangement
size
color
shape
inclusions |
|
|
Term
| marked rouleaux is normal in healthy horses, but if it is seen increased in other speicies this could indicate??? |
|
Definition
| increased fibrinogen or globulin |
|
|
Term
| an agglutenation saline test is postitive, what does the blood look like? |
|
Definition
|
|
Term
| 6 spiculated poikilocytes |
|
Definition
Echinocytes
karatocytes
schistocytes
Acanthocytes
Drepanocytes
Dacryocytes |
|
|
Term
|
Definition
|
|
Term
| 4 different catagories of shapes of poikilocytes |
|
Definition
Spiculated
spherocyte
stomatocyte
leptocytes |
|
|
Term
| echinocytes are usually an artifact, what errors could cause these on a smear? |
|
Definition
| old blood sample, EDTA excess, or PH change from slow drying |
|
|
Term
| health conditions that could cause echinocytes |
|
Definition
IN CANINE: renal disease
lymphosarcomas
rattlesnake bite
EQUINE: if blood is drawn in a "bleeder" (exercised induced pulmonary hemorrhage) after exercise |
|
|
Term
|
Definition
|
|
Term
| causes and conditions of schistocyte |
|
Definition
shearing by intravascular trauma
conditions that cause: DIC (disseminated intravascular coagulation), iron deficiency, vascular neoplasms (hemangiosarcoma) |
|
|
Term
|
Definition
iron deficiency
liver disorders
doxorubicin toxicity (in cats)
myelodyplasia (bone marrow disease) |
|
|
Term
| Acanthocyte causes and conditions |
|
Definition
cause: altered lipid metabolism
condition: hepatic lipidosis & other liver diseases
hepatic hemangiosarcoma |
|
|
Term
| drepanocytes are a normal in vitro change for what species |
|
Definition
| deer, angora goats, some sheep breeds |
|
|
Term
|
Definition
no longer biconcave
have a decresed diameter but a normal MCV
usually in dogs
no central pallor |
|
|
Term
| conditions to see spherocytes |
|
Definition
immune-mediated hemolytic anemia
transfusion with mismatched blood |
|
|
Term
|
Definition
thin erythrocytes
increased membrane or decreased volume |
|
|
Term
| conditions that leptocytes could be present |
|
Definition
non regenerative anemia
liver dieases |
|
|
Term
|
Definition
|
|
Term
|
Definition
almost always an artifact from using to much pressue when making smear
or can be caused by myeloproliferative disease |
|
|
Term
| erythrocyte morphology: inclusions |
|
Definition
basophilic stippling
howell jolly bodies
nRBCs
heinz bodies |
|
|
Term
| basophilic stippling species variance |
|
Definition
ruminants: common in immature RBCs
Feline: anemia response
canine: lead poisoning |
|
|
Term
|
Definition
nuclear remnants
large round spots
stain basophilic
observed in young RBC in anemia
can be normal in cats and horses (in low numbers) |
|
|
Term
| after a splenectomy or splenic disorder you might see increased numbers of which RBC inclusion? |
|
Definition
|
|
Term
|
Definition
areas of oxidized hemoglobin
protuberance attached to cell membrane
stain ligheter pink than RBC
|
|
|
Term
| conditions causing increase heinz bodies |
|
Definition
*onion poisoning*
*zinc poisoning*
*acetaminophen poisoning(tylenol)*
lymphoma
hyperthyroidsm
diabetes mellitus (RARE) |
|
|
Term
|
Definition
normal size RBC
conditions- secondary to chronic disorders
|
|
|
Term
|
Definition
larger RBC
conditions: regnerative anemia |
|
|
Term
|
Definition
smaller RBCs
conditions: iron deficiency |
|
|
Term
hemoglobin concentration classification:
normochromic |
|
Definition
normal hemoglobin concentration
conditions: most anemias |
|
|
Term
hemoglobin concentration classification
hypochromic |
|
Definition
reduced hemoglobin concentration
conditions: reticulocytes |
|
|
Term
mean corpuscular volume MCV
the volume of the average RBC |
|
Definition
MCV (femtoliters)= (PCV X 10)/RBC
do not convert the pcv into a decimal
femtoliters=fl |
|
|
Term
mean corpuscular hemoglobin (MCH)
the density or hgb within the RBC
|
|
Definition
MCH(picograms)= (hgb X 10)/ RBC
picograms=pg |
|
|
Term
Mean copuscular Hemoglobin concentration(MCHC)
average concentration of hemoglobin within RBC |
|
Definition
| MCHCG/dl = Hgb g/dl X 100/ PCV |
|
|
Term
| reticulocyte still have what remnant of a nucleus? |
|
Definition
|
|
Term
| what species has punctate reticulocyte |
|
Definition
|
|
Term
| life span of aggregate reticulocyte |
|
Definition
|
|
Term
| life span of punctate reticulocytes |
|
Definition
|
|
Term
| corrected reticulocyte percentage |
|
Definition
| observed retic % X patients PCV ÷ normal mean PCV |
|
|
Term
| absolute reticulocyte count |
|
Definition
|
|
Term
| species that does not release reiculocytes from bone marrow even if they have regenerateive anemia |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
