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Epi- lecture 14
Epi
16
Biology
Undergraduate 3
10/17/2012

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Term
Descriptive Epidemiology works with?
- key tools
Definition
outbreak investigation
surveillance
public health

key tools:
sampling
counting prevalence
incidence risk
incidence rate
Term
Definition of Epidemiology
Definition
study of the frequency, distribution and determinants of disease in populations and the applications of this study to control health problems
Term
Briefly list 5 ways to measure morbidity/mortality
Definition
counts
ratios
proportions
risks
rates
Term
Proportion is written as?
- discuss numerator and denominator
Definition
written as decimal, fractions or percentages
numerator is part of denominator
ie 300 females/400 total students
Term
risk is measured in?
expresses what?
Definition
proportions
expresses probability that something will occur.
ie probability of getting flu shot last year = got flu/total pop
Term
Rates express what?
measures what?
Definition
expresse occurrence of event in defined population in a specified period of time.
measures "speed"
ie incidence rate is 14 cases per 1000 person-years
Term
Case where 3 million cattle in july, 7500 farms and 500 cases of anthrax. give appropriate amount in counts, ratios, proportions and rates
Definition
count: 500 ratio: 1:6000 proportion: 0.02% rates: 2 cases per 10,000 cattle months at risk
Term
Counts used in?
problems?
Definition
used in census and surveys
problem: no denominator so don't know how bad it is
Term

proportion of group diseased

-formula

-used in?

Definition
number with disease (a)/ number (n) "at risk" of disease denominator (n) includes numerator (a) a/(a+b) used in census or sample
Term
prevalence -measured in? -units and range? - does it measure risk? why/why not?
Definition
prevalence relates to number of existing cases of disease of interest in population (at a certain point or period) - measured in proportion - has no units and ranges from 0 -->1 - is NOT a measure of risk because it doesn't take into account duration of disease or when disease occurred. The numerator includes individuals with disease that is of varying durations.
Term
Point Prevalence
- formula
Definition
proportion of population that has disease of interest at a particular time

point prevalence = number with disease at single point in time/ number in pop that can actually get disease at that point in time
Term
Period prevalence
- formula
Definition
Proportion of population that has disease of interest during certain period

period prevalence = number with disease during specific time period/ number in population that can actually get disease during that period of time
Term

Censoring

(4 types)

Definition

when an observation is stopped because of

end of study

person left cohort

was lost to follow up

or

died from cause OTHER than one of interest

Term
Incidence
-measures
-requirements
- give two formals for determining
Definition
a dynamic measure of disease occurrence
new disease occurs over time
- measures speed
- requires two or more observations or tests. the first to establish which individs are disease free, the second to identify which ones became diseased in intervening period.
- two formulas:
risk: new cases/population at risk
rate: new cases/ sum of person-time at risk
Term
difference between risk and rate when measuring incidence?
Definition
they have the same numerator, but different denominators.
risk measures new cases/population at risk
and
rate measures new cases/sum of person-time at risk
Term
risk aka cumulative incidence aka incidence risk
- measured in?
- units, range?
- formula
Definition
proportion of unaffected individuals, who, on average, will develop disease of interest over a specified time period
- measured in proportion
- no units, range 0-1
- risk = # new cases in population during specified time period/ initial NAR - 1/2 withdrawals during time period.
- NAR = number at risk (must have potential to become case at time 0)
- Withdrawals = individs that leave study for other reasons, but did not develop disease of interest.
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