Term
| what type of research is done to determine how big the problem is? |
|
Definition
|
|
Term
| what type of reaserch is doe to see if intervtion could work? |
|
Definition
|
|
Term
| what type of research is done to see if intervation works? |
|
Definition
|
|
Term
| describe systematic reviews |
|
Definition
evalute the evidnce for on-farm food saefty and large animal health/production interventions.
is concerned with reporting key features related to methodoligcal quality. |
|
|
Term
| which tests lead to proof of concept? |
|
Definition
| animal and laboratoy models |
|
|
Term
| whihc type of tests leads to hypothesis generating? |
|
Definition
| cross-sectional observational |
|
|
Term
| which tests lead to hypothsis testing under real-world conditions? |
|
Definition
|
|
Term
| describe randomized controlled trials |
|
Definition
- experimental units (individs or group) assigned to treatment or control and an outcome (disease) is compared between groups.
- investigator manipulates treatment assignments |
|
|
Term
| which test is considered the "gold standard" for evaluting efficacy of treatments/ interventions under "real world" conditions? |
|
Definition
| Randomized controll trials |
|
|
Term
| in a natural disease challange, the study population is representative of? |
|
Definition
|
|
Term
| list the 8 steps in systematic review |
|
Definition
1. assemble reivew team
2. question formulation
3. literautre search
4. relevance screening
5. quality assessment
6. data extraction and synthesis
7. written report
8. dissemination |
|
|
Term
| list 3 wyas internal validity can be messed up through failure to report: |
|
Definition
failure to report:
- random allocation to treatment groups
- blinding of persons administering treatment and persons evaluting outcome
- reporting number lost to follow up |
|
|
Term
| what things will neg effect external validity if failed to report? |
|
Definition
| detials of study pop, treatments given, method of assessing outcome, bacterial challenge (if applicable) |
|
|
Term
| what is the CONSORT statement? |
|
Definition
| agreed upon standard for reporting clinical trial results, orignally publisehd in 1996 |
|
|
Term
| why don't we use CONSORT for vet med? |
|
Definition
-"participants" coud either mean pet or owner
-we use "challenge trials" which are unique to vet med
- RCTs : different types (smal groups, comercial conditions, species of interest)
- alloacted of treatments to groups rather than iniviids |
|
|
Term
| REFLECT-LFS statement used for what? |
|
Definition
| livestocka nd food safety |
|
|
