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Endocrine System - 3
Exam
8
Biology
12th Grade
06/12/2012

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Term
What is somatotropin?
Definition
another hormone produced by the anterior pituitary
Term
What causes dwarfism in childhood?
Definition
low levels of GH
Term
What causes gigantism in childhood?
Definition
high levels of GH
Term
What is the result of high levels of GH in adulthood?
Definition
acromegaly where bones thicken instead of growing longer
Term
What does GH affect?
Definition
most cells, especially cartilage and growth plates
Term
What does GH increase?
Definition
- number of cells (hyperplasia) in soft tissues and bones
- cell size (hypertrophy) in muscle and connective tissues by promoting protein synthesis and inhibiting protein degradation
- fat breakdown to fatty acids
→ muscles use more fatty acids and less glucose => increases blood glucose levels
→ growth spurts accompanied by fat loss
✭ brain cells are glucose dependent and cannot metabolize fat for energy
Term
What does GH stimulate
Definition
liver to produce "insulin-like growth factors" that stimulates cells in growth plates → elongation of long bones
Term
What happens to GH with age?
Definition
declines
→ cellular repair and protein replacement is compromised
→ more protein is replaced by fat => changes body shape
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