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Embryology
Study of Babies
51
Biology
Undergraduate 4
05/07/2006

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Term
Congenital Defects
Definition
defects seen at time of birth
Term
Acquired Defects
Definition
defects that develop after birth due to mechanical weaknesses or disease
Term
Teratogen
Definition
anything that can cause an abnormality
Term
Hereditary Teratogens (cause of anomalies)
Definition
something genetically wrong
Term
Mutant Genes
Definition
genes that has been changed
Term
Hemophilia
Definition
'bleeders disease'
Term
Chromosome Derangements
Definition
Half Miscarriages
Term
Trisomy Babies
Definition
Have 47, rather then 46 chromosomes
Term
Trisomy 21
Definition
Down Syndrome
Term
Mosaic Down Syndrome
Definition
not inherited from parents - actually happens during embry development
Term
Trisomy 18 / Edward's Syndrome
Definition
extra chromosome is 18 - hairy, odd hand flex, rocker-bottom feet, 99% die in first month
Term
Trisomy 13 / Patau Syndrome
Definition
Bi-lateral cleft lip, rocker-bottom feet, retardation
Term
Aneuploidy
Definition
abnormal # of chromosomes
Term
Klienfelter's Syndrome
Definition
47 C's - extra one is sex chromosome

XXY
Term
Turner's Syndrome
Definition
only 45 C's - only one you can miss is X

XO
Term
Superfemale
Definition
XXX
Term
Jacob's
Definition
XYY
Term
Deletions
Definition
normal # of chromosomes, but a part is missing
Term
Cri-du-chat
Definition
part of 4 or 5 C missing - sounds like cat meowing
Term
Environmental Teratogens
Definition
Physical Agents
Chemicals
Infections
Term
Ionizing Radiation
Definition
Dont't get x-rays is preg
Term
Excessive heat during preg
Definition
could cause neurtal tube defect
Term
Horomone Imbalances
Definition
Insulin or tumor on adrenal gland
Term
Streptomycin
Definition
antibiotic - harms hearing, balance, equalibrium in baby
Term
Thalidomide
Definition
drug to help with morning sickness - harms babies (limb dev)
Term
Caffine
Definition
6 cups - 600mg - high risk of miscarriage
Term
Infections
Definition
German Measles or Rubella
Cytomegalovirus
Toxoplasmosis
Term
Toxoplasmosis
Definition
caused by protozoan > Toxoplasma gondi

(from cat fecal material)
Term
Types of Anomalies
Definition
Agenesis
Incomplete Development
Term
Agenesis
Definition
Failure of organ to develop
Term
Incomplete Development
Definition
Cleft lip & cleft palate
Term
Cleft lip
Definition
severe emotional upset 8-12 wk
Term
Teratology of Fallot
Definition
four parts of heart are messed up
Term
Neural Tube Defect
Definition
Nervous System is affected
*elevated alpha fetoprotein
-not enough folic acid
Term
Spina bifida
Definition
defect in the backbone & spinal cord
Term
anencephaly
Definition
born missing fore-brain
Term
Supernumerary Structures
Definition
born with extra mammary glands
Term
Hypertrichosis
Definition
excessive hairyness
Term
Meckel's Diverticulum
Definition
retention of embry structure (yolk sac)
Term
Situs Inversus
Definition
every organ is flipped opposite
Term
Teratomas
Definition
Tissues that show up anymore
-intestinal in mouth
-toe on ovary
Term
Phenylketonuria PKU
Definition
error of metabolism - baby missing enzyme, thus chemical reactions are very slow
>phenylalanine hydroxylase is missing
Term
Galactosemia
Definition
cannot have regular milk bc cannot break it down fast enough
Term
Varicocoel
Definition
vericos vein in scrotum is too big > too much blood > too warm
Term
Gonads
Definition
4-6 ?
8 > testes or ovary
Term
Phallus
Definition
Guy > penis
Girl > clitoris
Term
Genital Swelling
Definition
Fuse together > scrotum
Thicker & separates > labia majora
Term
Mullerian Ducts
Definition
2 paramesonephric ducts
> fallopiean tube & part of uterus & upper vagina

*degenerates in gusy
Term
Wolffian Ducts
Definition
2 mesonephric ducts
> epididymus & sperm ducts

*degenerates in girls
Term
Origin of Primoridal Germ Cells
Definition
Future Oogonia & Spermatogonia

-originate in yolk sac!
Term
Barr Body
Definition
rounded up, inactive X chromosome
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