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Embryology Urinary
Embryology Urinary
34
Science
Undergraduate 4
04/11/2009

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Term
How is the urogenital Ridge formed?
Definition
Is formed by intermediate mesoderm froms a longitudinal elevation along the dorsal body wall called urogenital ridge.
Term
What part of the urogenital ridge gives rise to the urinary system?
Definition
The nephrogenic system.
Term
What are the 3 sets of nephric structures that form the nephric structures
Definition
Pronephros, Mesonephros, Metanephros.
Term
What does the pronephros develop into?
Definition
Forms the pronephric tubules and pronephric duct. Cranial most nephric structure. transitory structure regresses completely by week 5 of development and is notfunctional in humans.
Term
Mesonephros
Definition
develops by differentiation to form mesonephric tubules and mesonephric duct. middle nephric strucure.partially transitory. most regresses but duct persists as urogenital sinus.
Term
Metanephros
Definition
from outgrowth of mesonephric duct. ureteric bud. caudal most nephric structure. week 5 functional in fetus at about week 10 of development.
Term
Metanephros further develops to kidney
Definition
ureteric bud penetrates metanephric mesoderm and divides to form ureters, renal pelvis, major & minor callyces, and collecting ducts.
Term
Nephron Formation
Definition
Metanephric vesicles differentiate into collecting tubule, distal convuluted tubule, loop of henle, proximal convoluted tubule. nephron formation complete at birth.
Term
Transitional epithelium of kidney
Definition
Transitional epithelium lining the ureter, pelvis, major calyx, and minor calyx, and simple cuboidal epithelium is from MESODERM
Term
Development of Urinary Bladder
Definition
Formed from upper end of urogenital sinus.
Term
What is the fate of allantois?
Definition
Becomes a fibrous cod, the urachus (median umbilical ligament) in the adult.
Term
Where do mesonephric ducts incorporate into the bladder?
Definition
At the trigone on the posterior wall.
Term
Where is the transitional epithelium of teh urinary bladder derived from?
Definition
Endoderm => comes from urogenital sinus and gut tube.
Term
How is the female urethra developed?
Definition
Lower end of urogenital sinus. develops from endodermal outgrowths to surrounding mesoderm. Ends at vestibule of vagina.
Term
Male Urethra
Definition
lower end of urogenital sinus. 1. Prostatic urethra into mesoderm form prostate gland. 2.Membranous outgrowth to mesoderm, bulbourethral glands. 3. Penile urethra develops endodermal outgrowths to surrounding mesoderm form Littre's glands.
Term
Distal part of penile urethra
Definition
formed from an ingrowth of surface ectoderm called glandular plate. joins penile urethra and becomes navicular fossa.
Term
How is the foreskin formed?
Definition
Ectodermal septa appear lateal to the navicular fossa.
Term
The stratified squamous epithelium lining the distal part of penile urethra is derived from where?
Definition
Ecotderm
Term
What are the two episodes in suprarenal cortex formation?
Definition
Fetal cortex present at birth but regresses by second postnatal month. Zona glomerulosa, Zona Fasiculata of definitive cortex present at birth but zona reticularis not formed until age 3.
Term
What causes Renal Agenesis?
Definition
Ureteric bufd fails to develop thereby eliminating induction of metanephric vesicles and nephron formation.
Term
What are the symptoms of unilateral Renal Agensis?
Definition
Is asymptomatic and compatible with life.
Term
What are the symptoms of Bilateral Renal Agenesis?
Definition
Causes oligohydramnios during pregnancy, which allows uterine wall to compress fetus, resulting in potter syndrome.
Term
What are the symptoms of potter syndrome?
Definition
Deformed limbs, abnormal facial appearance.
Term
Pelvic Kidney
Definition
Ectopic kidney that occurs when one or both kidneys fail to ascendand therefore remain in the pelvis or lower lumbar area.
Term
What is the term for when two pelvic kidneys fuse to form a solid mass.
Definition
Pancake kidney
Term
What occurs when inferior poles of kidneys fuse and normal ascent of kidneys is haulted?
Definition
Horseshoe kideny.
Term
What causes a duplication of the urinary tract
Definition
when ureteric bud prematurely divides before penetrating the metanephric mesoderm. results in either a double kidney or duplicated ureter and renal pelvis.
Term
What is the cause of polycystic disease of the kidneys?
Definition
loops of henle dilate, forming large cysts that severely compromise kidney function. relatively common hereditary disease. associated clinically with cysts of liver, pancreas, and lungs.
Term
What is Exstrophy of the bladder
Definition
occurs when the posterior wall of urinary bladder is exposd to exterior. failure of anterior abdominal wall and anterior wall of blader to develop properly.
Term
Urachal cyst or sinus
Definition
when remnant of allantois persists, thereby forming a cyst or sinus. found along midline on a path from umbilicus to apex of urinary bladder. often associated clinically with urine drainage from umbilicus.
Term
Ectopic Ureteric Orifices (males)
Definition
Ectopic ureter opens to neck of bladder or prostatic urethra
Term
Ectopic Ureteric Orifices (females)
Definition
opens into neck of bladder or vestibule of vagina.
Term
Neuroblastoma
Definition
most common extracranial solid cancer in infancy and childhood. neuroendocrine tumor. 60% found in extrasuprarenal sites along sympathetic chain ggl.
Term
Wilm's tumor
Definition
associated with urinary tract abnormalities, absence of iris, hemihypertrophy (enlargement of one side of body). tumor may become quite large but remains encapsulated.
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