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Embryology Lecture 10
Embryology Lecture 10
57
Science
Undergraduate 4
02/14/2009

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Term
Umbilical Vein
Definition
transports blood rich O2 and nutrients from placneta to fetal body. enters body through umbilical ring and travels along the anterior abdominal wall to liver. 1/2 to liver. 1/2 ductus venosus.
Term
Ductus Venosus Pathway.
Definition
travels short distance and joins inferior vena cava. oxygenated blood from placenta mixes with deoxygenated blood from lower parts of body.
Term
Inverior Vena Cava Pathway
Definition
enters right atrium, large proportion of it is shunted directly into the left atrium through an opening called foramen ovale
Term
Superior Vena Cava "pathway"
Definition
passes into the right venricle and out through the pulmonary trunk. 10% blood enters this circuit. Lungs are collapsed and vessels have high resistance. enouch reaches lung tissue to sustain them.
Term
Pulmonary Trunk Pathway
Definition
most bypasses lungs by entering ductus arteriosus connecting pulmonary trunk to descendingi portion of aortic arch. this allows low O2 concentration blood to bypass the lungs.
Term
Left Atrium Pathway
Definition
oxygenated blood enters left atrium through foramen ovale with small amount of deoxygenated blood returning from pulmonary veins. moves to left ventricle and pumped into aorta.
Term
Coronary Arteries
Definition
oxygenated blood can enter the myocardium through these.
Term
Carotid Arteries
Definition
some oxygenated blood can enter the myocardium through this.
Term
Descending Aorta
Definition
partially oxygenated and partially deoxygenated. some is carried to branches of aorta to various regions of body. rest passes to umbilical arteries
Term
Umbilical Arteries
Definition
branch from internal iliac arteries and lead to placenta where they can be reoxygenated.
Term
Inflation lungs on circulatory system
Definition
this reduces the resistance to blood flow through the lungs resultingin increased blood flow from the pulmonary arteries.
Term
Foramen Ovale Closure
Definition
increased left atrial pressure and decreased right atrial pressure forces blood against the septum primum causing foramen ovale to close. resulting in separation of heart into two pumps.
Term
Fossa Ovalis
Definition
what remains of the closed foramen ovale.
Term
Ductus Arteriosis closure
Definition
closed off within 1-2 days of birth and replaced by connective tissue known as ligamentum arteriosum.
Term
Failure of Ductus Arteriosus to close
Definition
is said to be patent. Results in marked elevation of pulmonary pressure because blood from aorta through ductus arteriosus to pulmonary arteries. can lead to irreversible degenerative changes in heart and lungs.
Term
Umbilical vein deactivation
Definition
becomes the round ligament of the liver when blood supply is cut off.
Term
Ductus Venosum
Definition
becomes the ligamentum venosum.
Term
Aortic Sac derivative
Definition
brachiocephalic artery(right) and part of ascending aorta, large parts of common carotid arteries.
Term
1st aortic arch
Definition
part of maxillary artery and external carotid arteries
Term
2nd aortic arch
Definition
part of hyoid and stapedial arteries, part of external carotids.
Term
3rd aortic arch
Definition
part of common carotids and first parat of internal carotid
Term
4th aortic arch(R)
Definition
small proximal part of the right subclavian artery.
Term
4th Aortic Arch (L)
Definition
small part of arch of the aorta just proximal to the left subclavian artery.
Term
6th aortic arch (R)
Definition
proximal part of right pu.monary artery
Term
6th aortic arch (L=ductus)
Definition
proximal left pulmonary artery and ligamentum arteriosum.
Term
Ductus Arteriosus
Definition
ligamentum arteriosum
Term
Dorsal Aorta
Definition
part of right subclavian, descending aorta below left subclavian unpaired ventral arteries: celiac, superior mesenteric, and inferior mesenteric arteries.
Term
Paired Dorsal Segmental Arteries
Definition
intercostal arteries and vertebral arteries
Term
Umbilical arteries
Definition
internal iliac, superior vesical arteries, medial umbilical ligaments.
Term
Posterior Cardinal Vein(R)
Definition
part of azygos vein and common iliac veins.
Term
Ductus Venosus
Definition
ligamentum venosum
Term
Umbilical Vein (L)
Definition
round ligament
Term
Vitelline Vein (R)
Definition
superior mesenteric Vein and IVC
Term
Vitelline Vein (L)
Definition
most of portal Vein
Term
Anterior Cardinal Veins
Definition
internal jugular veins (left brachiocephalic veins is an anastomosis)
Term
Anterior Cardinal Vein (R)
Definition
part of SVC and right brachiocephalic vein
Term
Common Cardinal Vein
Definition
proximal part of SVC
Term
Common Cardinal Vein (L)
Definition
lateral part of coronary sinus and oblique vein of left atrium
Term
Posterior Cardinal Vein (R)
Definition
part of azygos vein and common iliac veins
Term
Supracardinal Veins
Definition
hemiazygos vein (L) and caudal part of azygos vein (R)
Term
Subcardinal Vein (R)
Definition
renal segment of inferior vena cava.
Term
Ebstein's Anomaly
Definition
abnormality in tricuspid valve. 2 leaflets displaced downward to pumping chamber and thrid is elongated and may be adherent to wall. cause tricuspid to leak blood backwards to right atrium when ventricle contracts. Right atrium is enlarged, may be congestive heart failure.
Term
Clinical signs and symptoms of Ebsteins Anomaly
Definition
(cyanosis), tire easily, short of breath. heart skipping(palpitations), fast hart rate, shortness of breath, chest pain. growth and develpment normal.
Term
Treatment of Ebsteins anomaly
Definition
surgery.
Term
Tricuspid Atresia
Definition
there's no tricuspid valve so no blood can flow from the right atrium to the right ventricle. right ventricle is small and underdeveloped. survival depends on opening in wall between atria (atrial septal defect) and ventricals. kid appears blue
Term
Treatment of Tricuspid Atresia
Definition
children with tricuspid atresia need lifelong follow ups with a doctor to ensure health. risk of enfection before and after surgery. amoxicillin before dental work and certain surgeries to help prevent endocarditis.
Term
Membranous VSD
Definition
caused by faulty fusion of the right bulbar ridge, left bulbar ridge, and AV cushions. allows free flow of blood between right and left ventricles. large VSD initially associated with a L-R shunting of blood, increased pulmonary blood flow, pulmonary hypertension.
Term
Secondary effect of large VSD
Definition
hypertension of pulmonary arteries results in proliferation of tunica intima and tunica media of pulmonary muscular arteries and arteioles resulting in narrowing of lumen. pulmonary resistance increases higher than systemic resistance and R-L shunt begins and results in cyanosis=>Eisenmenger complex. most common type of VSD
Term
Muscular VSD
Definition
caused by single or multiple perforations in the muscular IV septum.
Term
Common Ventricle
Definition
caused by failure of the membranous and muscular IV septa to form.
Term
Isolated Dextrocardia
Definition
heart is abnormally positioned onthe right side of the thorax. Is usually associated with other sever cardiac anomalies.
Term
Dextrocardia with Situs Inversus
Definition
dextrocardia with inversion of the viscera . not usually associated with other server cardiac anomalies.
Term
Double Aortic Arch
Definition
occurs when an abnormal right aortic arch develps in addition to a left aortic arch due to persistence of the distal portino of the right dorsal aorta. Forms a vascular ring around the trachea and esophagus, which causes difficulties in breathing and swallowing.
Term
Right Aortic Arch
Definition
occurs when the entire right dorsal aorta abnormally persists and part of the left dorsal aorta regresses. right aortic arch may pass anterior or posterior to the esophagus and trachea. A retroesophageal right arch may cause difficulties in swallowing or breathing.
Term
Postductal coarctation of Aorta
Definition
occurs when the aorta is abnormally constricted; cause is unclear. found distal to the origin of the left subclavian artery and inferior to the ductus arteriosus.
Term
Postductal coarctation consequences
Definition
associated with increased upper extremity blood pressure, lack of pulse in femoral artery, high risk of cerebral hemorrhage and bacterial endocarditis. associated with turner syndrome. may occur superior to ductus arteriosus but very uncommon.
Term
Patent Ductus Arteriosus
Definition
when ductus arteriosus fails to close; normally functionally closes withn a few hours ater birth via smooth muscle contraction to ultimately form ligamentum arteriosum. causes shunting of blood from aorta back to pulmonary circulatiaon. treated with prostablandin synthesis inhibitors which promote closure. common in premature infants and maternal rubella infection.
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