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Embryogenesis of pituitary and repro system
ch 4 repro phys
25
Science
Undergraduate 4
10/04/2014

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Term
what to sections morph to form the anterior and posterior lobes of the pituitary gland?
Definition
posterior lobe- infundibulum
anterior lobe- Rathke's pouch
Term
what is the sphenoid bone?
Definition
develops around pituitary gland to protect it
Term
what is the sella turnica
Definition
the protective cavity that houses the pituitary gland
Term
at what time do germ cells start migrating
Definition
week 4 of gestation in cows and humans
Term
what happens when the primordial germ cells migrate to the gonadal ridge?
Definition
the form the primitive sex cords
Term
sections of fetal kidneys and fuction
Definition
pronephros- regresses
mesonephros- forms repro tract
metenephros- forms adult kindneys and ducts
Term
what 2 parts did the Jost Experiment look at
Definition
Mullarian Ducts
Wolffian ducts
Term
what part of the germ cells for the fetus? the placenta?
Definition
The ICM forms the fetus
the blastocoele forms the placenta
Term
what is the jost paradigm
Definition
chromosomal sex--gonadal sex--hormonal sex--phenotypic sex--behavioral sex
Term
what gene controls for sexual differentiation?
Definition
SRY gene on the Y chromosome (short arm)
Term
what is the function of the SRY gene?
Definition
transcription factor for primary sex chords, and Sertoli cells
Term
What important hormone do the Sertoli cells produce? What is the function of this hormone?
Definition
Anti-Mullarian hormone that causes Ledig cells to differentiate and produce testosterone
Term
What if there is no SRY gene present
Definition
the Wolffian ducts regress and Mullarian ducts begin to fuse and form cervix, uterus, and horns
Term
what product do the accessory sex glands produce that convert testosterone?
Definition
5 alpha reductase
Term
what does 5a-reductase do?
Definition
testosterone--> dihydrotestosterone (DHT)
Term
what hormones causes differentiation in sex in the brain?
Definition
testosterone is aromatized into estradiol, which can pass through the blood brain barrier and program male behavior
Term
what are phalates?
Definition
compounds that make plastic flexible, but ingestion interferes with testosterone and estrogen
Term
what prevents estrogen produced in ovaries from entering the brain and programming male behavior
Definition
alpha Fetal protein (aFP) binds to estrogen and prevents it from passing the barrier
Term
what is cryptochid?
Definition
germ cells fail to multiply and die. sertoli cells only in semineferous tubules
Term
what is an inguinal hernia>
Definition
when a part of the intestine gets past the inguinal loop and into the scrotum
Term
what causes a freemartin
Definition
sharing of blood and placenta with a male and female twin pair
get SRY gene in both
Term
what causes the testes to descend?
Definition
rapid growth then regression of the gubernaculum
Term
what hormones are required to tell the gubernaculum to grow?
Definition
testosterone and Insl-3 (insulin like 3)
Term
what is the location of the repro tract?
Definition
retroperitoneal (behind the peritoneum)
Term
what is a benefit of having a freemartin?
Definition
They are good at detecting estrus without risk of pregnancy
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