Term
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Definition
SnNout (if highly senstive and Negative it rules out the disease)
Proportion of True Positives
Few False Positives
=TP/(TP + FN) Disease + column |
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Term
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Definition
SpPin (if test is postive rules in disease)
Proportion of True Negatives
Very few False positives
= TN/(TN + FP) |
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Term
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Definition
the ability of a test to be correct on the
average. If a test is not accurate, it is biased. |
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Term
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Definition
known as reproducibility or
reliability is the ability of a measurement to give
the same result with repeated measurements. |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
number of people who are identified by test as positive and truly have disease
= TP/(TP +FN) |
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Term
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Definition
the proportion of
negative results that are true negatives
TN/(TN + FN) |
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Term
| Affect of prevalence of PPV |
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Definition
The higher the prevalence of a disease in a population, the higher
the PPV and the lower the NPV of a test for it |
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Term
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Definition
| pre-test and post-test probabilities are the same |
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Term
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Definition
increase probability of target disorder
LR > 10 large and often conclusive |
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Term
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Definition
| decrease probability of target disorder |
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Term
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Definition
Is the test Reproducible??
Studies account for inter-observer differences by having different observers
perform the same test, and measuring the agreement between them by
means of a kappa statistic. The kappa statistic takes into account the
amount of agreement that you would expect by chance.
Kappa = 0 = no agreement than you would expect by chance
Kappa = 1 = perfect agreement
Kappa = .6 = indicates good agreement |
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Term
| Screening tests should be used when... |
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Definition
1. The test is known to be accurate (sensitivity and specificity)
2. Screening for and treating early disease should improve health outcome |
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Term
| a 100% sensitivity test would get rid of what? |
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Definition
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Term
| a 100% specfic test would get rid of what? |
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Definition
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Term
| When should a highly senstive test be used? |
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Definition
1. early stages of diagnostic work up
2. Important penalty for missing the disease (TB, syphilis)
3. Screening Tests |
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Term
| When should a highly specific test be used? |
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Definition
1. To rule-in a diagnosis suggested by other tests
2. False positive tests will result in harm to patient (ex. chemotherapy) |
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Term
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Definition
plotting Sensitivity vs. 1-specficity
Most NorthWest corner is best |
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Term
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Definition
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