Shared Flashcard Set

Details

Dyslipidemia Statin
Dyslipidemia Statin
22
Pharmacology
Professional
09/11/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
Brand name for atorvastatin
Definition
Lipitor
Term
Brand name for Simvastatin
Definition
Zocor
Term
Brand name for Simvastatin/Ezetimibe
Definition
Vytorin
Term
Brand name for Rosuvastatin
Definition
Crestor
Term
Brand name for Pravastatin?
Definition
Pravachol
Term
Brand name for Lovastatin
Definition
Mevacor
Term
Brand name for Fluvastatin
Definition
Lescol, Lescol XL
Term
Doubling the dose of a statin will reduce LDL level by ?
Definition
3-6%
Term
Side effects of statins?
Definition

Myalgia, arhralgias, myopathy, rhabdomyolysis (increased risk with higher doses pitavastatin)

Term
Statins and muscle damage?
Definition
If present, should be seen right away!
Term
Statins and liver monitoring?
Definition

Check LFTs at the start (baseline) and at 3 months, and periodically afterwards (such as at annual physical)

 

Term
What are the two statins that don't need does adjustment in renal failure?
Definition
Lescol and Lipitor
Term
[image]
Definition

Statement. Not a question.

 

Term

Lovastatin, Simvastatin & Atorvastatin have an increased risk of musle damage with?

Definition

Amiodarone and other 3A4 inhibitors such as azole antifungals (flu, itra, keto, posa, and vori)....

 

just know the fungals

Term

Do not exceet ___ mg/d simvastatin in patients taking cyclosporine, danazol, or gemfibrozil

Definition
10
Term

Do not exceed ___ mg/d simvastatin in patients taking amiodaraone or verapamil.

Definition
20
Term

Do not exceed ___ mg/d simvastatin in patients taking diltiazem.

Definition
40
Term
Which statins can be taken at anytime of the day d/t to long T1/2?
Definition

Crestor

Lipitor

Pravachol

Livalo

[image][image][image][image]

Term
Which statin may increase INR for patients taking warfarin?
Definition
Rosuvastatin
Term
Cyclosporine can increase rosuvastatin; do not exceed ___ mg of rosuvastatin
Definition
5
Term
How is fluvastatin primarily metabolized?
Definition
2C9; monitor patients taking warfarin
Term
Are statins contraindicated in pregnancy?
Definition
YES! Do not use if pregnant or think you may be pregnant, or are planning to become pregnant.
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