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Drugs for the USMLE
Drills for all the drugs listed on my Drugs and Bugs blog.
16
Medical
Graduate
06/26/2014

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Cards

Term
K+ Sparing Diuretics
Definition
Spironolactone;
Triamterene;
Amiloride
Term
Spironolactone MoA
Definition
Aldosterone receptor agonist (competitive inhibition)
Term
Clinical uses of Spironolactone
Definition
Hyperaldosteronism;
CHF;
Weak anti-HTN;
Hypokalemia;
Female Hirutism
Term
Adverse SE's of Spironolactone
Definition
hyperkalemia, hyponatremia, gynecomastia
Term
Guanethidine MoA
Definition
Enters peripheral nerves via NE reuptake mechanism and blocks the release of NE storage vesicles
Term
"Typical" Antipsychotics
Definition
Thioridazone;
Haloperidol;
Fluphenazine;
Chlorpromazine
Term
"Typical" Antipsychotics MoA
Definition
D2 receptor blocker
Term
"Typical" Antipsychotic SE's
Definition
"Parkinsonian-like" symptoms:
Extrapyramidal system SE's,
Anticholinergic;
Neuroleptic malignant syndrome;
Tarditive dyskinesia
Term
Rule of 4's for Extrapyramidal SE's
Definition
4 hours of acute dystonia,
4 days akinesia,
4 weeks akathisia,
4 months+ tarditive dyskinesia
Term
Isoproterenol MoA
Definition
beta agonist: beta1 and beta2
Term
Therapetic use of Niacin (Vit B3)
Definition
Hyperlipidemia - decreases LDL and TAG's with possible small HDL increase
Term
NSAIDs
Definition
Ibuprofen;
Naproxen;
Indomethacin;
Ketorolac
Term
NSAID MoA
Definition
Reversibly inhibit cyclooxygenase (COX-1 and COX-2)
Term
Clinical use of NSAIDs
Definition
Analgesic;
Anti-inflammatory (high-dose);
Antipyretic
Term
NSAID that also closes a patent ductus arteriousus
Definition
Indomethacin
Term
NSAID SE's
Definition
GI disturbances, incl ulcers/bleeding,
Renal tox,
Aplastic anemia
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